CV Flashcards
MCC distributive shock
septic shock
normal urine output
0.5 mL/kg/hr
HTN Tx with diuretics
- thiazides.
- loop diuretics only if renal dysfn
ACE MOA
incr bradykinin, incr prostaglandins (vasodilator)
Kerley B lines
CHF
Tx HTN urgency/emergency
- nitroprusside.
- with MI: nitroglycerin, BB.
Tx aortic dissection
nitroprusside + BB + urgent surgery
S3 gallop
CHF
Elderly with suspected CHF. What else to order?
TSH (thyrotoxicosis causing CHF)
Acute & Chronic angina Tx
Acute: SL nitroglycerin, SL isosorbide.
Chronic: BB.
NSTEMI Tx
Antiplatelet (ASA, clopidogrel) + Anticoagulant (heparin, enoxaparin)
BB
STEMI Tx
ASA + clopidogrel
PCI or thrombolytics
Thrombolysis contraindications
- Absolute: hemorr stroke previously, stroke within 1yr, intracranial neoplasm, active bleed, aortic dissection
- Relative: trauma within 3-4wks, sure within 3wks, cardiopulm resuscitation, pre, PUD, anticoag use, BP>180, diabetic retinopathy
Tetralogy of Fallot
VSD, RV outflow obstruction (pulm stenosis), overriding aorta, RVH
widened pulse pressure
AR
midsystolic/ejection click
MVP
opening snap
MS
Holiday heart
A. fib with incr ETOH
Tx PSVT
adenosine, verapamil (CCB)
prevention: CCB, BB
Tx chronic A flutter
amiodarone
Brugada’s
asians, male, syncope, VF, sudden death
EKG: RBBB, ST elevation V1-3
Tx VT
cardioversion (unstable), amiodarone, procainamide, lidocaine (stable)
electric alternans
pericardial effusion (pathognomonic)
-cyclic shift in amplitude
pulsus paradoxus
cardiac tamponade, constrictive pericarditis, COPD
> 10mmHg decr SBP with inspiration
narrow pulse pressure
cardiac tamponade, AS
Endocarditis Dx
Duke
- 2 BC
- echo+
- new regurgitant murmur
minor: fever, petechiae, splinter hemorrhages, Osler, Janeway, Roth spots, glomerulonephritis
2major, 1+1, 3 minor
Tx endocarditis
Vanco + ceftriaxone
Vanco + gentamicin
NO anticoag
endocarditis prophylaxis
for invasive dental/surg and infected skin/I&D with:
- prosthetic valves
- previous endocarditis
- congenital heart dz/ HCM
- heart transplant/ heart repairs
-Amoxicillin
NOT for GI/GU, valvular dz
Rheumatic heart dz Dx
Jones
erythema marginatum
minor: fever, polyarthralgia, PR prolong, CRP
2major, 1+2
AND pos cult/rapid strep and strep Ab titer (ASO)
Tx rheumatic heart dz
IM PCN, bed rest, salicylates, corticosteroids
intermittent claudication
PAD
PAD of the iliac artery (Leriche’s syndrome) leads to what?
erectile dysfunction
ABI
PAD
PAD Tx
Cilostazol (antiplatelet for intermittent claudication)
no smoking, exercise, lipid lowering, sildenafil, thromboendarterectomy
Tx venous ulcers
leg elevation, compression bandage/boot
DVT definitive Dx
venography
DVT Tx
lovenox (LMWH)
Giant cell arteritis highly associated with what?
Polymyalgia Rheumatica
- elderly female
- severe stiffness: neck, shoulders, upper back, pelvic girdle
- ESR incr
- Tx: NSAIDS, prednisone/steroids
Giant cell arteritis Tx
high dose prednisone, low dose ASA
MCC aortic aneurysm
atherosclerosis
others: Marfans, Ehlers Danlos
Indications for AAA repair
- > 5.5 cm
- growth >0.5 cm in 6mo
- symptomatic
AAA study of choice
US
BB and HF
BB Tx chronic CHF
BB contraindicated in acute CHF
Digoxin toxicity
Bradycardia
Heart block, ectopy (PVC, VT, PAC)
Hyperkalemia
predisposing to dig toxicity: hypoK, hypoMg
Tx: Fab Ab
Beck’s triad
pericardial tamponade
- muffled/distant heart sounds
- HOTN
- incr JVP
pericardial knock
constrictive pericarditis (pericardial thickening/calcification)
3rd heart sound
Kussmaul’s sign
pericardial tamponade, constrictive pericarditis
-incr JVP with inspiration
MCC acute pericarditis and myocarditis
viral
Enteroviruses (COXSACKIE B, echovirus)
Mobitz I
Wenckebach
progressive PR lengthening
Mobitz II, where?
bundle of HIS
constant prolonged PR
to 3rd AV block
Tx bradycardia
ATROPINE
epi, dopamine, pacemaker
location of MI: lat, ant, inf
lat: circumflex
ant: LAD
inf: right coronary
incr aldosterone does what?
incr Na
Dx ACS with baseline ECG abnorm
pharmacologic stress test (adenosine, dipyridamole)
contraindication to treadmill stress test
baseline ECG abnorm, too fat
contraindication to pharmacologic stress test
bronchospastic dz
Tx Prinzmetal’s, cocaine use MI
Prinzmetal’s: CCB
Cocaine: CCB, nitrates, benzos
S3, S4
S3: systolic HF
S4: diastolic HF
Cheyne Stokes
L-sided CHF
normal EF
55-60
CHF Tx: Na restriction, fluid restriction
Na:
ADR loop diuretics, thiazides
hypoNa, hypoK, hyperuricemia, hyperglycemia
ADR K sparing diuretic
gynecomastia, hyperK
pos inotropic
digoxin, dobutamine, epi
batwing on CXR
CHF
MCC dilated cardiomyopathy
idiopathic
other: enterovirus, ETOH, cocaine, preg, doxorubicin
MCC restrictive cardiomyopathy
amyloidosis
incr/decr HCM murmur
decr: squatting
incr: standing, valsalva
Tx HCM
BB
erythema marginatum
rheumatic fever
MCC rheumatic fever
GABHS (S pyogenes)
squatting in murmurs
increases
decr HCM
standing, valsalva in murmurs
decreases
incr HCM
handgrip in murmurs
incr AR, MR, MS
holosystolic murmurs
VSD (harsh), MR/TR (blowing), PDA (continuous machinery), Tetralogy of Fallot (harsh)
widely split S2
MR, ASD
Rheumatic heart dz associated with what murmur?
MS
Tx regurgitation murmurs
vasodilators
Rib notching
coarctation of aorta
Coarctation of aorta: gold standard Dx
angiogram
HTN retinopathy findings
arterial narrowing, AV nicking, hemorrhages, soft exudates
Stage IV: papilledema
Tx HTN emergency
1st line: Nitroprusside IV
enceph: Nitroprusside
Cerebral infarction/hemorr, aortic dissection: labetalol
Nitro IV, Hydralazine
Tx HTN urgency
Clonidine PO
LDL goals: CAD/DM, RF for CAD, everyone else
CAD/DM: 130
RF for CAD (HTN, smoking, HDL50y/o): 160
everyone else: 190
Drug for LDL
Statins
Drug for TG
Fibrates
Drug for HDL
Niacin
HDL is NIce
lipid lowering drug to avoid in DM
Niacin (hyperglycemia)
Lipid screening start at what age?
> 35 y/o
Niacin ADR
hyperglycemia, hyperuricemia (gout), hepatotoxicity
Fibrates ADR
gallstones, myositis/myalgias
Omega 3 for?
TG
What to give prior to Niacin to decr flushing?
ASA or ibuprofen
Leriche syndrome
PAD
Claudication, impotence, decr femoral pulses
Areas of PAD sx in aortic bifurcation/iliac, femoral A, popliteal A.
iliac: buttock, hip, groin
femoral A: thigh, upper calf
popliteal A: lower calf
MC PAD location
femoral A: thigh, upper calf
MC AAA location
infrarenal
thoracic aneurysm test of choice
CT
AAA >4cm and >3cm management
> 4: monitor with US Q6mo
>3: monitor Q1yr
aortic aneurysm gold standard test
angiography
MC aortic dissection site
ascending aorta (type A)
aortic dissection gold standard test
MRI angiography
Tx types of aortic dissection
type A (proximal/ascending): surgery type B (distal/descending): medical (BB)
Amaurosis fugax
Giant cell arteritis
anterior ischemic optic neuritis
central retinal artery occlusion
Giant cell arteritis Bx findings
Temporal artery Bx: mononuclear lymphs infiltration, multinucleate giant cells
Giant cell arteritis Tx
high dose corticosteroids (60mg/day x 6wks)
Giant cell arteritis - arteries involved?
external carotid A. -> temporal, occipital, ophthalmic
Polymyalgia Rheumatica associated with what?
Giant cell arteritis
Tx Raynaud’s
CCB
Thromboangiitis obliterans / Buerger dz: Sx, Tx, population
Sx: thrombophlebitis, claudication, Raynauds
**population: young, tobacco
Tx: tobacco cessation
hypercoagulability etiologies
malignancy…
Trousseau’s sign
Superficial thrombophlebitis
migratory thrombophlebitis
= malignancy, vasculitis
most specific DVT sx
unilat edema
abnormal Allen test
thromboangiitis obliterans (Buerger dz)- nonatherosclerotic dz of sm/med vessels
cerulea alba, cerulea dolens
Alba: white milky pallor ->
Dolens: cyanosis, swelling of limb with sudden pain
-DVT
false pos D-dimer
pregnancy
DVT gold standard Dx, Tx
gold standard Dx: venography
Tx: heparin, LMWH -> warfarin x 3-6 mo
extrinsic factors
II, VII, IX, X, protein C/S
heparin, warfarin pathways
heparin: intrinsic (in a relationship), PTT
warfarin: extrinsic (exes at war), PT
Medial/Lateral malleolus ulcer
Medial: venous
Lateral: arterial
Venous ulcer Tx
wet to dry dressings, hyperbaric O2, edema Tx
shock physiology
metab acidosis, LA, sympathetic stim, RAAS stim
MAP goal
65-90
fluid loss sx 40%
40%: no UOP
PCWP (pulm cap wedge pressure) shock
hypovol: decr
cardio: incr
obstructive: incr
distrib: decr SVR (Sys vasc resistance)
neuro shock sx
HOTN, bradycardia
septic shock sx
INCR CO*** (only one) = warm extrem
decr SVR
when to use mechanical valve replacement
MC mets to heart
malignant melanoma
SLE assoc with what cardiac dz?
pericarditis
early morning hrs CP
Prinzmetal’s
pos tox screen (cocaine, ETOH), CHF (dyspnea)
dilated cardiomyopathy