Cushing's vs Addison's

Question 1

Which One?

Overproduction of ACTH thus releasing too much glucocorticoids.

Answer 1

Cushing’s - remember with Cushing’s hormones are High so they are CUSHioned

Question 2

Which One?

Insufficient ACTH, and/or cortisol, aldosterone and androgens

Answer 2

Addison’s - remember with Addison’s cortisol is low so we need to ADD them

Question 3

Most common cause: STOPPING long term use of corticosteroids

Answer 3

Addison’s

can be caused by abruptly stopping _____

Question 4

Can be caused by long term use of corticosteroids

Answer 4

Cushing’s

long term use of?

Question 5

Which One

Buffalo hum, mid section obesity with skinny arms and legs

Answer 5

Cushing’s

physical changes

Question 6

Which One?

Hyperglycemia

Answer 6

Cushing’s

sugar

Question 7

Bruise easily

Answer 7

Cushing’s

blood vessels

Question 8

striae

Answer 8

Cushing’s

skin

Question 9

osteoporosis and muscle wasting

Answer 9

Cushing’s

bones and muscles

Question 10

moon face

Answer 10

Cushing’s-

facial changes

Question 11

HTN

Answer 11

Cushing’s

Question 12

Heart Failure

Answer 12

Cushing’s

Question 13

hair growth effected

Answer 13

Cushing’s

Question 14

menses eases and most common age for women is 20-40

Answer 14

Cushing’s

Question 15

INCREASED Sodium

Answer 15

Cushing’s

Question 16

DECREASED Potassium

Answer 16

Cushing’s

Question 17

Treatment is Mitotane

Answer 17

Cushing’s

Question 18

muscle weakness, anorexia and fatigue

Answer 18

Addison’s,

general symptoms

Question 19

bronze/dark pigmentations of mucous membranes and skin

Answer 19

Addison’s-

skin changes

Question 20

DECREASED sodium

Answer 20

Addison’s

sodium

Question 21

DECREASED glucose

Answer 21

Addison’s

glucose

Question 22

INCREASED Potassium

Answer 22

Addison’s

K+

Question 23

postural hypotension

Answer 23

Addison’s

BP

Question 24

cyanosis, vascular collapse, renal shutdown, extreme dehydration and systemic shock

Answer 24

Addison’s Crisis -

Emergency - s/s

Question 25

INCREASED Glucose

Answer 25

Cushing’s

glucose

Question 26

Hirsutism

Answer 26

Cushing’s

hair

Question 27

Craving Salty Food’s

Answer 27

Addison’s

cravings

Question 28

hypercalcemia

Answer 28

Addison’s

calcium

Question 29

hypogycelmia, hyponatremia, hyperkalemia, hypercalcemia

Answer 29

Addison’s

four electrolytes Na, K, Ca and sugar

Question 30

Meds: glucocorticoids and gluco/mineralocorticoid combos

Answer 30

Addison’s

Meds

Question 31

Avoid caffeine and alcohol

Answer 31

Addison’s -

avoid what?

Question 32

high protein and high carb diet

Answer 32

Addison’s

diet

Question 33

ACTH is produced where

Answer 33

Pituitary glad

Question 34

Side effects of treatment for Addison’s..

corticosteroid treatment

Answer 34

signs of Cushing’s

this can be a side effect of what?

Question 35

Stress or illness can increase effects of this disease and require increase in medication

Answer 35

Addison’s

effect of stress and illness

Question 36

Immunosuppression

Answer 36

Cushing’s-

effects on immune system

Question 37

Meds: Hormone suppressants
Bromocriptine (Parlodel)
mitotane (Lysodren)
aminoglutethimind (Cytadren)

Answer 37

Cushing’s

meds used