CTL Flashcards

1
Q

Names the steps of mitosis, in order

A
  1. G1
  2. S
  3. G2
  4. Prophase
  5. Metaphase
  6. Anaphase
  7. Telophase
  8. Cytokinesis
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2
Q

What are the 6 types of epithelia?

A

Simple, Simple Cubodial, Simple Columnar, Stratified (squamous), Pseudostratified (columnar), transitional

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3
Q

What are the functions and location of simple squamous epithelia?

A

Functions: diffusion and filtration

Present in: kidneys, blood vessels, serosae, lining of heart

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4
Q

What are the functions and location of simple columnar epithelia?

A

Functions: absorption and secretion

Present in: Digestive tract and gallbladder, urine tubes and some regions of the uterus

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5
Q

What are the functions and location of simple cuboidal epithelia?

A

Functions: secretion and absorption

Present in: kidneys, ducts and secretory of small glands, and ovary surface

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6
Q

What are the functions and location of stratified squamous epithelia?

A

Functions: Protection

Present in: external part of the skins epidermis, lining of oesophagus, mouth and vagina

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7
Q

What are the functions and location of pseudostratified columnar epithelia?

A

Functions: secretion and propulsion of mucus

Present in: male sperm carrying ducts and trachea

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8
Q

Mitochondria is?

A

the powerhouse of the cell

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9
Q

What does the Rough ER do?

A

Synthesizes proteins for secretion

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10
Q

Smooth ER is?

A

Site of lipid synthesis and carbohydrate metabolism. Detoxifies both drugs and alcohol

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11
Q

What does the Golgi apparatus do?

A

modifies new proteins for lysosomes, secretion and plasma membrane

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12
Q

What does the lysosomes do?

A

Digest things that enter cell by endocytosis. Digests remains after cell death. Remove and recycle bad organelles and cell components

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13
Q

Cytoskeleton is?

A

structural support to cell. Cell division. assists motility and cytosol streaming

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14
Q

Aetiology is?

A

causes

- two classes: genetic and acquried

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15
Q

Pathogensis is?

A

sequence of cellular, biochemical and molecular events that occur after exposure of cells or tissues to an injurious agent

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16
Q

Morphological changes are?

A

structural alterations in cells or tissues that are either characteristic of a disease or diagnostic of aetiologic process

17
Q

Functional abnormalities are?

A

End results of genetic, biochemical and structural changes in cells and tissues.

Lead to clinical manifestations

18
Q

Clinical manifestations are?

A

the functional consequence of functional abnormality changes

19
Q

How do cells respond to stress?

A
  • normally maintain homeostasis
  • adaption
  • cell injury
    however injury can be reversible, but in some cases irreversible
20
Q

What are the 2 types of irreversible cell injury?

A

necrosis and apoptosis

21
Q

What are the types of cellular adaptions?

A

Physiological (hormones and endogenous chemical mediators) and pathological (structure and function)

22
Q

Hypertrophy is?

A

increase of cell size = increase of organ size

  • occurs when cells are incapable of dividing
  • occurs due to increased production of cellular proteins
23
Q

Hyperplasia is?

A
  • increase in number of cells
  • adaptive response in cells capable of replication
  • physiological: occurs when a portion of the tissue is removed
  • Pathological: caused by excessive hormonal or growth factor stimulation
24
Q

Atrophy is?

A
  • decrease in cell size = decrease in organ size
  • causes include: aging, decreased work load, loss of innervation, decreased blood supply, inadequate nutrition and loss of endocrine stimulation
25
Q

Metaplasia is?

A
  • Reversible change in which one cell type is replaced by another
  • sensitive cells are replaced with better ones that can withstand stress
26
Q

What are the 2 intrinsic systems that make up the immune system?

A

Innate: first and second line of defense (external body and mucus)
Adaptive: third line of defense (attacks foreign substances)

27
Q

What are the physical and chemical defenses used by the skin and mucous membranes?

A

Physical: skin, mucous, tears, saliva, urine flow, vomiting
Chemical: sebum, lysozyme, gastric juice

28
Q

What are the types of internal defenses?

A

antimicrobial proteins, cells, inflammation and fever

29
Q

What are the 2 types of adaptive immunity?

A

cellular (T cells) and humoral (B cells)

30
Q

What does the Sodium Potassium pump do?

A

maintains the Na and K concentration gradietns

31
Q

What is a passive channel?

A

a membrane ion channel that is always open

32
Q

what is a chemically gated channel?

A

a channel opened by binding of specific neurotransmitter

33
Q

What is a voltage gated channel?

A

Opens and closes in response to MP

34
Q

What is a mechanically gated channel?

A

Opens and closes in response to physical deformation of receptors

35
Q

What is the balance of Na and K in and around cells?

A

Na+ is higher concentrated outside than inside the cell

K+ is higher concentrated inside than outside of the cell