CT Disorders Flashcards
What is the etiology for SLE?
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What is the Hx/PE for SLE?
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What are the diagnostics for SLE?
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What is the tx for SLE?
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What are the management/prevention strategies for SLE?
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What is the prognosis/mortality for early SLE, years after the diagnosis?
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What is the prognosis/mortality for later SLE?
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What is primary anti-phospholipid Ab syndrome (APS)?
without SLE (have only APS)
What is secondary APS?
APS with SLE
What are the 3 Abs associated with APS?
Anti-cardiolipin Abs (aCL), lupus anticoagulant (LA), beta 2 glycoprotein 1 (anti-beta2 GPI)
What are anti-cardiolipin Abs (aCL)?
Cause biologic false positive tests for syphilis
Non-treponemal tests (RPR and VRDL)
Due to cross reactivity
What are lupus anti-coagulants (LA)?
Sort of a misnomer
In vivo = procoagulant
In vitro - prolongs clotting times (PTT), not corrected by adding normal platelet free plasma
What is the treatment for APS?
indefinite systemic anti-coagulation
What is the etiology for lupus-like syndrome/drug induced lupus (DIL)?
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What is the hx/PE for lupus-like syndrome/drug induced lupus (DIL)?
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What are the diagnostics for lupus-like syndrome/drug induced lupus (DIL)?
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What is the treatment for lupus-like syndrome/drug induced lupus (DIL)?
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What is the etiology for neonatal lupus?
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What is the hx/PE for neonatal lupus?
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What are the diagnostics for neonatal lupus?
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What is the tx for neonatal lupus?
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What is the etiology for discoid lupus?
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What is the hx/PE for discoid lupus?
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What are the diagnostics for discoid lupus?
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What is the tx for discoid lupus?
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Whats on the Ddx for discoid lupus?
Tinea infection
psoriasis
morphed (localized scleroderma)
What is the etiology for scleroderma?
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What is the hx/PE for scleroderma?
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What is the tx for scleroderma?
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What is the etiology for localized scleroderma?
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What is the hx/PE for localized scleroderma?
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What are the diagnostics for localized scleroderma?
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What is the tx for localized scleroderma?
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What is the etiology for limited (cutaneous) scleroderma?
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What is the hx/PE for limited (cutaneous) scleroderma?
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What are the diagnostics for limited (cutaneous) scleroderma?
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What is the tx for limited (cutaneous) scleroderma?
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What is the etiology for diffuse (cutaneous) scleroderma?
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What is the hx/PE for diffuse (cutaneous) scleroderma?
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What are the diagnostics for diffuse (cutaneous) scleroderma?
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What is the tx for diffuse (cutaneous) scleroderma?
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What are the skin manifestations of systemic sclerosis?
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What are the pulmonary manifestations of systemic sclerosis?
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What are the renal manifestations of systemic sclerosis?
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What are the endocrine manifestations of systemic sclerosis?
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What are the MSK manifestations of systemic sclerosis?
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What are the cardiac manifestations of systemic sclerosis?
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What are the GI manifestations of systemic sclerosis?
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What is the etiology for Sjogren syndrome?
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What is the Hx/PE for Sjogren syndrome?
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What are the diagnostics for Sjogren syndrome?
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What is the tx for Sjogren syndrome?
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What is the etiology for inflammatory myopathies?
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What is the hx/PE for inflammatory myopathies?
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What are the diagnostics for inflammatory myopathies?
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What is the tx for inflammatory myopathies?
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What is the hx/PE for dermatomyositis (DM)?
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What are the diagnostics for dermatomyositis (DM)?
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What is the tx for dermatomyositis (DM)?
glucocorticoids
What is the Hx/PE for polymyositis (PM)?
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What are the diagnostics for polymyositis (PM)?
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What is the tx for polymyositis (PM)?
glucocorticoids
What is the Hx/PE for inclusion body myositis (IBM)?
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What are the diagnostics for inclusion body myositis (IBM)?
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What is the tx for inclusion body myositis (IBM)?
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