Cryoglobulinaemic Vasculitis - SMALL CELL Flashcards

1
Q

Cryoglobulinaemic Vasculitis is a form of small vessel vasculitis where immune complexes that precipitate at temperatures lower than 37°C and are deposited on small vascular endothelium, causing vasculitis. What is the incidence of this?

1 - 1 in 100,000
2 - 10 in 100,000
3 - 100 in 100,000
4 - 1000 in 100,000

A

1 - 1 in 100,000

Affects Europeans most

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2
Q

Cryoglobulinaemic Vasculitis is a form of small vessel vasculitis where immune complexes that precipitate at temperatures lower than 37°C and are deposited on small vascular endothelium, causing vasculitis. What is the mean age that is affected by this condition?

1 - 70-80
2 - 50-60
3 - 40-60
4 - 20-40

A

3 - 40-60

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3
Q

Cryoglobulinaemic Vasculitis is a form of small vessel vasculitis where immune complexes that precipitate at temperatures lower than 37°C and are deposited on small vascular endothelium, causing vasculitis. Does this affect men or women more?

A
  • males
  • 3:1
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4
Q

Although there are multiple conditions linked with cryoglobulinaemic Vasculitis, which condition has been attributed to causing 90% of cases?

1 - hepatitis C
2 - HIV
3 - Covid-19
4 - lung cancer

A

1 - hepatitis C

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5
Q

What are the immune complexes typically composed of that cause cryoglobulinaemic vasculitis?

1 - IgA and IgM
2 - Ig and complement proteins
3 - Ig and IgA
4 - complement proteins and IgA

A

2 - Ig and complement proteins

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6
Q

Cryoglobulinaemic vasculitis can cause a variety of symptoms, including which of the following?

1 - Palpable purpura and necrotic ulcers
2 - Arthritis or arthralgia
3 - Kidney involvement (Membranoproliferative nephritis)
4 - Constitutional symptoms
5 - Neurological - weakness, peripheral neuropathy
6 - all of the above

A

6 - all of the above

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