Behçet Disease

Question 1

Behçet disease is a rare autoimmune disease that can affect all sizes of blood vessels. Does it affect arteries or venules only, or both?

Answer 1

• both are affected

Question 2

Behçet disease is a rare autoimmune disease that can affect all sizes of blood vessels. What is the incidence of Behçet disease in the UK?

1 - 0.6 : 100,000
2 - 6 : 100,000
3 - 60 : 100,000
4 - 600 : 100,000

Answer 2

1 - 0.6 : 100,000
- most common in Turkey and middle east

Question 3

Behçet disease is a rare autoimmune disease that can affect all sizes of blood vessels. What age does this most commonly affect?

1 - 10-20
2 - 20-30
3 - 30-40
4 - 40-50

Answer 3

2 - 20-30
- males and females are equally affected

Question 4

Behçet disease is a rare autoimmune disease that can affect all sizes of blood vessels. Which of the following is NOT a typically clinical sign of Behçet disease?

1 - Oral ulcers
2 - Urogenital ulcers
3 - Cutaneous lesions
4 - Respiratory distress
5 - Neurological disease
6 - Vascular disease
7 - Arthritis
8 - Cardiac involvement

Answer 4

4 - Respiratory distress

Question 5

Which human leukocyte antigens (HLA) is associated with Behçet disease?

1 - HLA-B27
2 - HLA-DR2
3 - HLA-B51
4 - HLA-QR2

Answer 5

3 - HLA-B51

Question 6

Which 2 inflammatory markers are typically raised in Behçet disease?

1 - amyloid B
2 - complement proteins
3 - ESR
4 - CRP

Answer 6

3 - ESR
4 - CRP

Question 7

Which test can be used to diagnose Behçet disease?

1 - pathergy test
2 - patch testing
3 - blood coagulation test
4 - ANCA test

Answer 7

1 - pathergy test

• patient is pricked into dermis
• skin is reassessed in 2 days
• skin should heal
• positive test is an erythamatous lump showing an over reaction of the immune system

Question 8

Which 2 of the following can be used to treat Behçet disease?

1 - NSAIDs
2 - Immunosuppression (steroids)
3 - Steroid sparing agents (azathioprine)
4 - antivirals

Answer 8

2 - Immunosuppression (steroids)
3 - Steroid sparing agents (azathioprine)