CRVO Flashcards
What is CRVO?
Central Retinal Vein Occlusion (CRVO) is a blockage of the central retinal vein, leading to vision problems.
What are common causes of CRVO?
- Age
- Systemic hypertension (HBP)
- Diabetes
- Arteriosclerosis
- Smoking
- Raised intraocular pressure (IOP)
- Hyperviscosity syndromes
What are the key signs of CRVO?
- Flame haemorrhages
- Retinal oedema
- Cotton wool spots
- Dilated and tortuous obstructed vein
- Narrow, sheathed artery
- Indistinct optic nerve head (ONH)
- Decreased visual acuity (VA)
- Relative afferent pupillary defect (RAPD) if ischaemic
What are the common symptoms of CRVO?
- Sudden painless loss of vision
- Blurred vision
- Altitudinal visual loss in BRVO
What are signs of non-ischaemic CRVO?
- Visual acuity ≥ 6/30
- Mild tortuosity and dilation of veins
- Dot/blot and flame-shaped haemorrhages
- Optic disc, retinal, and macular oedema
- ± RAPD
What are the signs of ischaemic CRVO?
- Visual acuity < 6/36
- Capillary closure and retinal hypoxia
- Severe vein tortuosity
- Extensive deep blot and flame-shaped haemorrhages
- Severe macular and disc oedema
- RAPD
What complications can arise in ischaemic CRVO?
- Iris neovascularisation (rubeosis iridis)
- New vessels on the retina (NVE) or disc (NVD)
- Rubeotic glaucoma (90-day glaucoma)
- Vitreous haemorrhage
- Tractional retinal detachment
What is BRVO?
Branch Retinal Vein Occlusion (BRVO) involves a wedge-shaped retinal area following the affected vein.
What are the signs of BRVO?
- Flame haemorrhages
- Dot and blot haemorrhages
- Cotton wool spots
- Hard exudates
- Retinal oedema
- Dilated tortuous veins
How is non-ischaemic BRVO different from ischaemic BRVO?
Signs of occlusion are more extensive in ischaemic BRVO, including neovascularisation (NVE, NVD).
What are differential diagnoses for CRVO?
- Ocular ischaemic syndrome
- Asymmetrical diabetic retinopathy
- Idiopathic retinal telangiectasia (type 1)
- Hypertensive retinopathy
- Choroidal neovascularisation
How should an optometrist manage CRVO?
- Best corrected visual acuity assessment
- Colour fundus photography
- Gonioscopy (if ischaemic CRVO is suspected)
- Optical coherence tomography (OCT)
- IOP check
- Urgent referral to an ophthalmologist and GP
What investigations may be conducted for CRVO?
- OCT
- Fluorescein angiography or OCT angiography
- Gonioscopy (if ischaemic)
- Ultrasound (if vitreous haemorrhage is present)
- Blood tests (FBC, serum glucose, ESR)
What is the treatment for macular oedema in CRVO?
Intravitreal anti-VEGF injections, such as ranibizumab (Lucentis) or aflibercept (Eylea).
What alternative treatments are available for macular oedema in CRVO?
Intravitreal steroids, such as Ozurdex (dexamethasone implant).