crossword study guide exam 2

Question 1

What measures prothrombin activity in serum after coagulation has taken place?

Answer 1

prothrombin consumption

Question 2

A whitish filamentous protein/clot formed by the action of thrombin and fibrinogen

Answer 2

fibrin

Question 3

A screen for all types of circulating anticoagulants based on the ability of normal plasma to correct an abnormal clotting time with a factor deficiency

Answer 3

mixing studies

Question 4

commercially prepared concentrate to the vitamin K dependent factors in lyophilized form, used to treat some hemorrhagic disorders

Answer 4

prothrombin complex

Question 5

inherited deficiency of factor VIII:C

Answer 5

Hemophilia A

Question 6

procoagulant portion of factor VIII complex

Answer 6

Factor VIII:C

Question 7

congenital deficiency of factor VIII:vWF and secondarily factor VIII:C resulting in mucocutaneous hemorrhagic disorder

Answer 7

Von Willebrands Disease

Question 8

Genetic characteristic located on the X or Y chromosome

Answer 8

Sex linked

Question 9

Test used to distinguish between factor VII and factor X deficiency

Answer 9

Stypven time

Question 10

Substance used to delay or prevent clotting

Answer 10

anticoagulant

Question 11

system that contains factors XII, XI, IX, and VIII, leads to the common pathway and is surface (contact) activated

Answer 11

intrinsic

Question 12

Term of genetic inheritance in which a characteristic cannot be expressed unless it is carried by both members of a homologous set of chromosomes

Answer 12

recessive

Question 13

Factor IX deficiency

Answer 13

Hemophilia B

Question 14

Single donor therapeutic plasma product containing all clotting factors

Answer 14

Fresh Frozen plasma

Question 15

Acquired inhibitors of normal coagulation, directed against a specific factor or a complex of factors

Answer 15

circulating anticoagulant

Question 16

Factor VIII:C

Answer 16

anti hemophiliac factor

Question 17

Factor V deficiency

Answer 17

parahemophilia

Question 18

Factor II

Answer 18

prothrombin

Question 19

“easy” bleeder, mostly men

Answer 19

hemophiliac

Question 20

process of stopping blood flow from a wound

Answer 20

coagulation

Question 21

prothrombin is the substrate for formation of this substance

Answer 21

thrombin

Question 22

trait with moderate bleeding diathesis in which PT is normal, APTT is slightly prolonged and is not corrected by incubation and levels of all known coagulation factors are normal

Answer 22

Passovoy

Question 23

High Molecular Weight Kininogen

Answer 23

Fitzgerald

Question 24

Pathway containing factors X,V,II,I

Answer 24

Common

Question 25

Factor that stabilizes the soluble fibrin gel

Answer 25

FSF

Question 26

Factor VII

Answer 26

Proconvertin

Question 27

Deficiency causes parahemophilia

Answer 27

Proaccelerin

Question 28

Stuart-Prower factor

Answer 28

Factor X

Question 29

Deficiency of this, primarily found in Ashkenazi Jews and sonsanguineous relationships, causes hemophilia C

Answer 29

PTA

Question 30

Process by which body controls clotting and bleeding

Answer 30

hemostasis

Question 31

Thrombin acts on this to form fibrin

Answer 31

fibrinogen

Question 32

Measures intrinsic system activity, examples are Lee-White and Hemochron

Answer 32

Whole blood clotting time

Question 33

System containing factor VII

Answer 33

extrinsic

Question 34

substance which, in the presence of ionized calcium, converts factor VII to VIIa

Answer 34

tissue thromboplastin

Question 35

disorder in which fibrinogen is qualitatively abnormal

Answer 35

Dysfibrinogenemia

Question 36

Factors II, VII, IX, and X are dependent on sufficient quantities of this for production in the liver

Answer 36

vitamin K

Question 37

disorder manifesting decreased levels of fibrinogen

Answer 37

hypofibrinogenemia

Question 38

presence of this may lead to thrombosis

Answer 38

Lupus anticoagulant

Question 39

test monitoring the extrinsic system

Answer 39

pro thrombin time

Question 40

substance extracted from the venom of a snake Bothrops atrox; used in coagulation procedure to resolve discrepant results when the thrombin time is prolonged due to heparin

Answer 40

reptilase

Question 41

factor IX

Answer 41

Christmas Factor

Question 42

test that monitors the conversion of fibrinogen to fibrin

Answer 42

Thrombin time

Question 43

Prekallikrein is also known as?

Answer 43

Fletcher factor

Question 44

substance used as a surface activator in APTT testing

Answer 44

kaolin

Question 45

substance that acts as a contact activator causing the release of PF3 and the activation of the intrinsic system

Answer 45

Celite