cross sectional and longitudinal studies Flashcards
what are the two ways results are analysed from a survey
- Descriptive statistics
- Associations between potential causes and effects
sample size
bigger is better but also more expensive
what is a type 1 and type 2 error
type 1 is a false positive (saying they are diseased when they are not)
type 2 is a false negative (saying they aren’t diseased when they are)
what’s power
the ability of a statistical test to find a significant result when it is real
helps you to avoid type 2 errors
whats the power calculation
p ±1.96√p(1-p)/n
what is a longitudinal study
- also known as cohort studies
- follow a group of people over time
- the group is called a cohort
- cohort is a group of people with similar characteristics
example of a longitudinal study
1) pick a group of people
2) measure any factors you consider relevant to your study (age, weight, job type)
3) give them free eye test every year
4) record how many get myopia, hyperopia, glaucoma, cataract
repeat for many years
how to calculate incidence rate in 1 year
number of new cases in 1 year / number not already a case at start of year
incidence as patient years
new cases/ per 1000 patients/ per 1 year
or
new cases/ per patient year
how to work out patient years
number of patient x years followed
100 patients for 1 year (100x1=100)
1 patient for 100 years (1x100=100)
50 patients for 2 years (50x2=100
basic cohort study design
- The original cohort must include people who might get the disease
- The original cohort must include people
- Who have been exposed to the risk factor
- Who have not been exposed
- Comparison of disease rates between exposed/not exposed will show association.
- If risk occurs before disease, strong evidence of causation