Clinical trials Flashcards
what is a clinical trial
- test of whether a treatment or some other procedure works
- it needs to be a fair test
the sensitivity of a diagnostic criterion (decision) is defined as…
…the fraction of sick patients who are diagnosed correctly
what is sensitivity and specificity
sensitivity is the probability of a correct diagnosis when the person is sick
specificity is the probability of a correct diagnosis when the person is not sick
what is positive predictive value (PPV)
probability that a diagnosis of a disease is correct
not the same as sensitivity
Negative Predictive Value (NPV)
The NPV is the probability that a diagnosis of no disease is correct
how to work out PPV
Count all people who fit in the criterion
only some of them will ACTUALLY have it
do actual over total of ppl who fit in the criterion