Crohns Disease and Ulcerative Colitis Flashcards
1
Q
What gender does CROHNS affect more?
A
Male
2
Q
What gender does ULCERATIVE COLITIS affect more?
A
Female
3
Q
Aetiology of Inflammatory bowel disease (4)
A
- Immunological
- Psychological
- Smoking
- Genetic
4
Q
Aetiology of Crohns disease (3)
A
- Granulomatous inflammation
- Food intolerance
- Viral infection
5
Q
Define a granuloma
A
Collection of multinucleate giant cells in a clump
6
Q
How does crohns disease present clinically?
A
Cobble stone lumps as a result of an oedema formation
7
Q
Crohns sites
A
Anywhere
8
Q
Ulcerative colitis sites (2)
A
Colon
Rectum
9
Q
Features of Ulcerative colitis
A
- Disease continuous
- Rectum always involved
- Anal fissures 25%
- Ileum involved 10%
- Mucosa gran. + ulcers
- Vascular
- Serosa normal
10
Q
Features of Crohns disease
A
- Discontinuous
- Rectum involved 50%
- Anal fissures 75%
- Ileum involved 30%
- Mucosa cobbled + fissures
- Non vascular
- Serosa inflamed
11
Q
Ulcerative colitis symptoms (2)
A
- Diarrhoea
2. Abdominal pain
12
Q
Colonic disease (2) Small bowel disease (2) and mouth (1)
symptoms
A
COLONIC DISEASE
- diarrhoea
- adbominal pain
SMALL BOWEL DISEASE
- pain
- malabsorption
MOUTH
- orofacial granulomatosis
13
Q
What age group is orofacial granulomatosus frequently seen in?
A
6-13 years
14
Q
Orofacial granulomatosus clinical features (3)
A
- Lip and oral swelling
- Angular chelitis
- Red inflamed gingiva
15
Q
IBD investigations (4)
A
- Blood tests
- Anaemia
- CRP
- ESR - Faecal calprotetectin
- Endoscopy
- Barium studies
