creatine kinase Flashcards
1
Q
which cells is creatine kinase in high concentrations?
A
muscle and brain
2
Q
what happens when muscle or brain cells die?
A
creatine kinase released into blood stream
3
Q
how many isoenzymes of creatine kinase are there?
A
three MM, MB, BB
4
Q
where is the MB form found
A
myocardium (heart muscle)
5
Q
which isoenzyme moves closest to negative electrode?
A
MM
6
Q
what is a myocardial infarct?
A
death of heart muscle cells
7
Q
how can we use creatine kinase levels to diagnose damage to tissues?
A
high MM levels for muscle damage
high MB levels for heart damage
high BB levels for brain damage
8
Q
what other markers are there of myocardial damage?
A
serum glutamate oxaloacetate transaminase(SGOT)
lactate dehydrogenase (LDH)
cardiac troponin
