creatine kinase Flashcards

1
Q

which cells is creatine kinase in high concentrations?

A

muscle and brain

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2
Q

what happens when muscle or brain cells die?

A

creatine kinase released into blood stream

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3
Q

how many isoenzymes of creatine kinase are there?

A

three MM, MB, BB

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4
Q

where is the MB form found

A

myocardium (heart muscle)

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5
Q

which isoenzyme moves closest to negative electrode?

A

MM

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6
Q

what is a myocardial infarct?

A

death of heart muscle cells

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7
Q

how can we use creatine kinase levels to diagnose damage to tissues?

A

high MM levels for muscle damage
high MB levels for heart damage
high BB levels for brain damage

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8
Q

what other markers are there of myocardial damage?

A

serum glutamate oxaloacetate transaminase(SGOT)
lactate dehydrogenase (LDH)
cardiac troponin

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