CPT PKPD Flashcards
1
Q
difference between partial and full agonist
A
can have same affinity
BUT partial have lower efficacy!!
2
Q
effect of rate of infusion on plasma steady state?
A
no effect
still takes 4-5 half lives even if quicker rate (plasma levels will inc)
3
Q
what is phase 2 metabolism
A
conjugation reactions e.g. sulfation and gulcuronidation
4
Q
what is phase 1 metabolism
A
oxidation or reduction
