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Clinical Conditions > CPT Drugs List - CVS > Flashcards

CPT Drugs List - CVS Flashcards

1
Q

Types of diuretics

A

Thiazides and thiazides like
Loop
Potassium sparing
Aldosterone antagonist

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2
Q

Thiazides and thiazides like diuretics

A

Bendroflumethiazide, Indapamide

Inhibition of Na/Cl co-transporter in distal convoluted tubule

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3
Q

Loop diuretics

A

Bumetanide, Furosemide

Inhibition of Na/K/2Cl co-transporter in the loop of Henle

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4
Q

Potassium sparing diuretics

A

Amiloride

Block ENaC at the luminal surface of the renal tubule

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5
Q

Aldosterone antagonist diuretics

A

Spironolactone

Compete with aldosterone at mineralocorticoid receptor

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6
Q

Antiarrhythmics

Classes

A 
Class I
Class II
Class III
Class IV
Unclassified
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7
Q

Class I antiarrhythmics

A

Flecainide (1C), Lidocaine (1B)

Na channel blockers

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8
Q

Class II antiarrhythmics

A

Bisoprolol, Metoprolol

Beta adrenoceptor blockers

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9
Q

Class III antiarrhythmics

A

Amiodarone, Sotalol

Potassium channel blockers

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10
Q

Class IV antiarrhythmics

A

Diltiazem, Verapamil

Calcium channel blockers

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11
Q

Unclassified antiarrhythmics

A

Adenosine - Adenosine receptor agonist (A1 in SA and AV nodes)
Atropine - Muscarinic antagonist
Digoxin - Inhibition of Na/K-ATPase
Ivabradine - Inhibition of If current in SAN

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12
Q

Beta adrenoceptor blockers

A

Atenolol, Labetalol, Propranolol

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13
Q

Alpha adrenoceptor blockers

A

Doxazosin, (Tamsulosin)

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14
Q

ACE inhibitors (ACEi)

A

Lisinopril, Ramipril

Inhibit angiotensin converting enzyme

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15
Q

Angiotensin receptor blockers (ARB)

A

Candesartan, Losartan

AT1 receptor antagonist

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16
Q

Nitrates

A

Glyceryl trinitrate, Isosorbide mononitrate

Soluble guanylyl cyclase activation - elevate cGMP - vasodilation

17
Q

Calcium channel blockers

A

Amlodipine, Diltazem, Nimodipine, Verapamil

Inhibition of L-type calcium channels - tissue selective

18
Q

Vitamin K antagonist

A

Warfarin

Vitamin K epoxide reductase inhibition

19
Q

Unfractionated heparin (UFH)

A

Heparin

Inhibition of active clotting factors - Xa and IIa (thrombin)

20
Q

LMWH

A

Dalteparin, Enoxaparin

Inhibition of active clotting factor Xa

21
Q

Synthetic (heparin) pentasaccharide

A

Fondaparinux

Inhibition of active clotting factor Xa

22
Q

Direct acting oral anticoagulants (DOACs)

A

Apixaban, Edoxaban, Rivaroxaban - inhibition of active clotting factor Xa
Dabigatran - inhibition of active clotting factor IIa (thrombin)

23
Q

Heparin reversal

A

Protamine Sulphate

Cationic peptide that binds to heparin forming inactive ion pair

24
Q

Warfarin reversal

A

Vitamin K1, Prothrombin complex concentrate

Promote production of clotting factors

25
Q

Antiplatelet agents

A

Aspirin - reduction of TXA2 synthesis by COX-1 inhibition
Dipyridamole - phosphodiesterase inhibitor and inhibition of adenosine Resp take in platelets
Clopidogrel, Prasugrel, Ticagrelor - ADP (P2Y12) receptor antagonists
Abciximab - irreversible binding of GPIIb/IIIa receptors

26
Q

Fibrinolytics

A

Alteplase, Streptokinase

Bind to and activate plasmin from plasminogen

27
Q

Antifibrinolytics

A

Tranexamic acid

Inhibit the activation of plasminogen from plasmin

28
Q

Types of lipid-lowering drugs

A

Statins
Fibrates
Cholesterol absorption inhibitors
PCSK9 inhibitors

29
Q

Statins

A

Atorvastatin, Simvastatin

Inhibit the rate limiting step of the mevalonate pathway (HMG-CoA reductase inhibitors)

30
Q

Fibrates

A

Fenofibrate

PPAR-alpha activator

31
Q

Cholesterol absorption inhibitors

A

Ezetimibe

NPC1L1 transporter inhibition

32
Q

PCSK9 inhibitors

A

Alirocumab

Monoclonal antibody that inhibits the PCSK9 enzyme

Clinical Conditions (14 decks)

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