CPIA Practice Questions Flashcards

From CPIA Facebook Group

1
Q

USDA-APHIS Animal Care Resource Policy #12 “Considerations of Alternatives to Painful/Distressful Procedures” states that when a database search is the primary means of considerations to alternatives of painful and distressful procedures, that a narrative should include all of the following except:
A. The name of the databases searched
B. The date the search was performed
C. The specific field of study
D. The search strategy (including scientifically relevant terminology) used

A

C. The specific field of study

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2
Q

Which of the following should be considered a significant change to an animal use proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration

A

C. change in anesthetic agent

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3
Q

Which of the following entities are required to release information per the Freedom of Information Act?
A. OLAW
B. AAALAC
C. IACUC
D. HSUS

A

A. OLAW

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4
Q

Training and instruction of personnel must include guidance in which of the following areas?
A. Effective writing of animal use proposals
B. Proper use of personal protective equipment
C. Appropriate communication with animal activist groups
D. Research or testing methods that limit the use of animals

A

D. Research or testing methods that limit the use of animals

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5
Q

Which of the following procedures may correctly be applied to Designated Member Review?
A. The IACUC Chair appoints one member to do the Designated Member Review.
B. The designated member reviewer is authorized to approve, require modifications, or disapprove the proposal.
C. All members receive information about the proposal and send their votes to the designated member reviewer for tallying.
D. Designated member review may be utilized to review proposals when there is insufficient time to notify the full membership of the proposal details.

A

A. The IACUC Chair appoints one member to do the Designated Member Review.

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6
Q

In which of the following circumstances may animal work begin before receipt of IACUC approval?
A. It is a continuing study awaiting three year renewal and for which the renewal protocol has been submitted to the IACUC.
B. It is a small pilot study on non-AWAR species.
C. It is a teaching activity that uses students’ personally owned dogs and cats.
D. There are no circumstances in which animal work may begin before IACUC approval.

A

D. There are no circumstances in which animal work may begin before IACUC approval.

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7
Q

Which of the statements below about the responsibility and authority of the Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal care and use program.
B. The IO must be the institution’s Chief Executive Officer.
C. The IO may not reinstate an animal activity that was previously suspended by the IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.

A

C. The IO may not reinstate an animal activity that was previously suspended by the IACUC.

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8
Q

With regard to conducting official IACUC business, the definition of a quorum is:
A. More than fifty percent (a majority) of voting members.
B. Fifty percent of voting and non-voting members combined.
C. More than fifty percent (a majority) of voting and non-voting members combined.
D. Fifty percent of the voting members.

A

A. More than fifty percent (a majority) of voting members.

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9
Q

The proper sequence for a designated member review by the IACUC is:
A. Review materials are sent to all voting members, full committee review is not requested by any member, the chairperson assigns one or more IACUC members as designated reviewers.
B. Review materials are sent to a quorum of designated reviewers, review results are solicited from designated reviewers, full committee approval of results is requested.
C. Review materials are sent to all voting members, a majority of members do not request full committee review, the chairperson assigns one or more IACUC members as designated reviewers.
D. Review materials are sent to a quorum of voting members, a majority of a quorum does not request full committee review, the chairperson assigns one or more IACUC members as designated reviewers.

A

A. Review materials are sent to all voting members, full committee review is not requested by any member, the chairperson assigns one or more IACUC members as designated reviewers.

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10
Q

Notifying investigators of IACUC protocol review outcomes in writing is:
A. A common courtesy not required by regulatory authorities.
B. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the minutes have been prepared and approved by the IACUC during a convened meeting.
C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.
D. Allowed by the USDA Animal Welfare Act Regulations and PHS Policy only after the IO is notified of the review outcome.

A

C. Required by both the USDA Animal Welfare Act Regulations and PHS Policy.

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11
Q

According to the Animal Welfare Act Regulations of the USDA, when conducting a semi-annual evaluation, the IACUC must conduct the evaluation:
A. With at least 1 IACUC member and allow participation by any member who wishes to do so.
B. With at least 2 IACUC members and allow participation by any member who wishes to do so.
C. With a majority of IACUC members present, including the non-affiliated member.
D. With all IACUC members present.

A

B. With at least 2 IACUC members and allow participation by any member who wishes to do so.

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12
Q

Who is given the authority to decide if a deficiency identified during a semi-annual IACUC evaluation is significant or minor?
A. The IACUC and IO together.
B. The veterinarian and the IACUC together.
C. Only the IACUC.
D. Only the IO.

A

A. The IACUC and IO together.

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13
Q

What information must be provided in the report for deficiencies identified during the IACUC semi-annual self-evaluation?
A. A reasonable and specific plan and schedule for correcting significant deficiencies, and a description of minor deficiencies.
B. A reasonable and specific plan for correcting significant and minor deficiencies and a schedule for completing the corrective actions.
C. The name and title of the IACUC member who will perform the corrections and the institutional official in charge of verifying the corrections.
D. The name and title of institutional support personnel who will provide the corrections and the IACUC members in charge of verifying the corrections.

A

B. A reasonable and specific plan for correcting significant and minor deficiencies and a schedule for completing the corrective actions.

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14
Q

Which of the following institutions must follow the PHS Policy?
A. Institutions that use any animals for research, teaching, or testing.
B. Institutions that use vertebrate animals for research, teaching, or testing.
C. Institutions that accept USDA research funds.
D. Institutions that accept PHS funding.

A

D. Institutions that accept PHS funding.

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15
Q

The three Rs of Russell and Burch stand for what?
A. Research, refinement, and recovery.
B. Replace, recognize, and recover.
C. Replacement, reduction, and refinement.
D. Research, results, and review.

A

C. Replacement, reduction, and refinement.

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16
Q

What is a primary mission of the Animal Welfare Information Center (AWIC)?
A. Publishes the Animal Welfare Act Regulations and Standards.
B. Provides assistance with alternatives and database searches.
C. Publishes the Guide for the Care and Use of Laboratory Animals.
D. Provides assistance with identifying the best laboratory animal cage washing equipment.

A

B. Provides assistance with alternatives and database searches.

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17
Q

Which agency requires an annual report of the number of animals used by pain/distress category?
A. American Association for Laboratory Animal Science
B. Association for Assessment and Accreditation of Laboratory Animal Care
C. Office of Laboratory Animal Welfare
D. United States Department of Agriculture

A

D. United States Department of Agriculture

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18
Q

Regarding studies with infectious agents in animals, as the BSL and ABSL number increases from 1 to 4, what happens to the containment and safeguard practices?
A. They become less important.
B. They become less stringent.
C. They become more vague.
D. They become more stringent.

A

D. They become more stringent.

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19
Q

U.S. Government Principles on the Use of Animals in Research state that:
A. Relief of pain should be provided for vertebrate animals except for birds, mice and rats.
B. Animals will show evidence of pain if a procedure causes them pain.
C. Pain is perceived differently by animals than by humans.
D. Procedures that are painful to humans should be assumed to cause pain in animals unless there is evidence to the contrary.

A

D. Procedures that are painful to humans should be assumed to cause pain in animals unless there is evidence to the contrary.

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20
Q

REVISED SAMPLE QUESTION ABOUT IO AUTHORITY - to improve clarity and correct misperception in previous wording. Which of the statements below about the responsibility and authority of the Institutional Official (IO) is false?
A. The IO must have authority to commit institutional resources in support of the animal care and use program.
B. If the IO is not the institution’s Chief Executive Officer, then the CEO must delegate IO authority to that person in writing.
C. The IO may not reinstate an animal activity that was previously suspended by the IACUC.
D. The IO may suspend an animal activity that was previously approved by the IACUC.

A

C. The IO may not reinstate an animal activity that was previously suspended by the IACUC.

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21
Q

PHS policy states that the OLAW requires assurance renewal every:
a) three years
b) up to five years
c) four years
d) depends on the institution and program size

A

b) up to five years

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22
Q

The guide incorporated two must haves: Disaster Planning and Emergency Preparedness which involved:
a) triage plans for personnel and animals
b) emergency contacts for all researchers and staff
c) plans include satellite facilities and provisions on euthanasia
d) coordinated by the institutional official

A

c) plans include satellite facilities and provisions on euthanasia

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23
Q

For the VA semiannual program review and facility inspection report, which of the following need not be included:
a. Date of the review/inspection
b. Names of individuals responsible for corrective actions
c. The signatures of the majority of the voting members
d. The timeline for the corrective actions
e. The reason for the deficiency

A

c. The signatures of the majority of the voting members

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24
Q

The 8th addition of the guide incorporated new additions to the guide: IACUC, IACUC Training, Personnel Security, Investigating and Reporting Animal Welfare Concerns, Veterinary Clinical Care Management, Drug Storage and Control. According to the Guide, what item not a requirement for IACUC members:
a) Formal orientation to the institution’s program
b) Training by a certified veternaian on all procedures involving animals
c) Training on how to review protocols as well as evaluate the program
d) Training on how to inspect facilities and labs where animal use or housing occurs
e) Training on legislation, regulations, guidelines, and policies

A

b) Training by a certified veterinarian on all procedures involving animals

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25
Q

Which of the following is not required for IACUC membership according to the Ag Guide:
a. veterinarian with training or experience in laboratory animal science and medicine
b. scientist with training or experience in agricultural animals
c. a person whose primary concerns are in an area outside of science
d. a person who is not affiliated with the institution

A

a. veterinarian with training or experience in laboratory animal science and medicine

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26
Q

USDA Regulations require the following IACUC members:
1. Veterinarian, chair, nonaffiliated
2. Veterinarian, chair, scientist
3. Veterinarian, nonaffiliated, scientist
4. Veterinarian, nonaffiliated, nonscientist

A
  1. Veterinarian, chair, nonaffiliated
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27
Q

PHS Policy requires the following IACUC members:
1. Veterinarian, chair, nonscientist, nonaffiliated
2. Veterinarian, chair, nonaffiliated, scientist
3. Veterinarian, nonaffiliated, scientist, nonscientist
4. Veterinarian, nonaffiliated, nonscientist, statistician

A
  1. Veterinarian, nonaffiliated, scientist, nonscientist
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27
Q

PHS and AWRs state that all records should be kept for a minimum of:
a) indefinite
b) 1-2 years
c) 3 years
d) 10 years

A

c) 3 years

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28
Q

PHS institutional Assurance is approve up to____years where as USDA registration is updated every____years:
a) 3yrs PHS and 5 years USDA
b) up to 5 years for phs and 3 years FOR usda
c) up to 5 years for both
d) 3 years for both

A

b) up to 5 years for phs and 3 years FOR usda

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29
Q

Which is not required when filing a PHS Institutional Assurance:
a) dates of faclity inspections
b) IACUC member roster
c) Number of covered species used annually
d) Lines of authority
e) species housed and average daily inventory by species

A

c) Number of covered species used annually

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30
Q

If the institution is PHS assured and is not AAALAC accredited, what must be included in the annual report to OLAW?
a) The IACUC minutes
b) The intuitional official’s assurance statement
c) Semiannual IACUC report
d) none of the above

A

c) Semiannual IACUC report

31
Q

What are the two circumstances the you would submit a semiannual report to OLAW?

A

At the request of OLAW or your institutional is not assured by a accrediting body such as AAALAC

32
Q

What line of authority submits the annual report to OLAW?

A

The IO

33
Q

When there are allegations of concerns on animal care and use, what are recommended steps for the IACUC when investigating the concern:

A
  1. the chair convene a meeting of the IACUC
  2. IO should be notified
  3. the AV should be involved in the investigation
  4. suspend research activity
34
Q

If a facility that receives DoD funds is under USDA investigation- who must they notify?

A

The facility must notify DoD and have a site visit within 30 days of notification.

35
Q

Who develops and issues joint service regulations to implement the Department of Defense Directive number 3216.1?

A

The Secretary of the Army as Executive Agent

36
Q

DoD Activities performed or sponsored in foreign countries shall follow what?

A

All applicable US requirements, as well as regulations and standards of the host country.

37
Q

The non-affiliated member(s) on a DoD IACUC may be?

A

A federal employee with demonstrated commitment to the community.

38
Q

The Joint Technical Working Group (JTWG) acts as a central advisory committee to who?

A

The Armed Services Biomedical Research Evaluation and Management (ASBREM) Committee.

39
Q

Which regulations are applicable to the Department of Defense?

A
  1. Animal Welfare Act; Animal Welfare Regulations
  2. The Guide for the Care and Use of Laboratory Animals; The Guide for the Care and Use of Agricultural Animals in Agricultural Research and Teaching
  3. The Lacey Act; Marine Mammal Protection Act; Endangered Species Act; Convention on International Trade in Endangered Species of Wild Fauna and Flora
40
Q

The Executive Agent for the Department of Defense Directive number 3216.1 is the _____
a. Director, Defense Research and Engineering
b. Secretary of the Army
c. Commander, US Army Veterinary Command
d. Inspector General
e. Under Secretary of Defense for Acquisition and Technology

A

b. Secretary of the Army

41
Q

According to the 8th edition of the Guide Each institution must or should have an occupational health program in place consist with federal, state and local regulations?
a) must
b) should

A

a) must

42
Q

Which of the following is not typically a function of the IACUC?
A. Investigate allegations of animal mistreatment, and suspend approved research if conducted out of compliance.
B. Communicate with the Institutional Official in matters pertaining to the animal care and use program.
C. Review and score scientific value for animal protocols submitted.
D. Review and approve proposed animal research.

A

C. Review and score scientific value for animal protocols submitted.

43
Q

Which of the following is a required member of the IACUC?
A. Institutional Official
B. Animal Facility Manager
C. Individual not otherwise affiliated with the institution
D. Representative from a local animal advocacy organization

A

C. Individual not otherwise affiliated with the institution

44
Q

According to USDA Regulations, an IACUC may have no more than how many members from any one administrative unit?
A. 2
B. 3
C. 4
D. 5

A

B. 3

45
Q

Which of the following statements concerning confidentiality of IACUC business is false?
A. Trade secrets, processes, operations, and style of work may not usually be revealed to outsiders by IACUC members.
B. It is against the law for an IACUC member to use information gained during IACUC meetings to his or her financial advantage.
C. It is unlawful for any IACUC member to release certain confidential information about the research facility in some situations.
D. Confidentiality requirements prohibit IACUC members from reporting violations of the Animal Welfare Act Regulations or PHS Policy.

A

D. Confidentiality requirements prohibit IACUC members from reporting violations of the Animal Welfare Act Regulations or PHS Policy.

46
Q

What do the Animal Welfare Act Regulations state about IACUC members who report violations to USDA?
A. They may be subjected to reprisals if in violation of local IACUC policy.
B. They may be subjected to reprisals if contact with USDA is not approved by IACUC Chair.
C. It is against the law for anyone to discriminate against them or subject them to reprisals.
D. Local institutional policy can discourage them from reporting violations of the regulations to USDA.

A

C. It is against the law for anyone to discriminate against them or subject them to reprisals.

47
Q

OLAW recommends which of the following reporting lines within an animal care and use program?
A. IACUC reports to the Attending Veterinarian
B. Attending Veterinarian reports to the Institutional Official
C. Institutional Official reports to the IACUC
D. Attending Veterinarian reports to the IACUC

A

B. Attending Veterinarian reports to the Institutional Official

48
Q

Which of the following statements about OLAW’s guidance on the use of carbon dioxide as a euthanasia agent is false?
A. Carbon dioxide must be supplied only from compressed gas cylinders.
B. Chambers should be pre-filled to lessen animal anxiety when placed inside.
C. Death must be verified before disposal of the carcass.
D. Unintended recovery of animals after CO2 euthanasia must be reported to OLAW.

A

A. Carbon dioxide must be supplied only from compressed gas cylinders.

49
Q

Which of the following statements about IACUC suspensions of animal activities is false?
A. USDA Animal Welfare Act Regulations and PHS Policy allow the chairperson or another IACUC member to suspend an animal activity on behalf of the IACUC.
B. Once the IACUC suspends an activity, it must report the suspension to the IO, who must report it to regulatory agencies.
C. A majority of a quorum must vote at a convened meeting to suspend an activity.
D. An institutional official can suspend an activity without agreement by the IACUC.

A

A. USDA Animal Welfare Act Regulations and PHS Policy allow the chairperson or another IACUC member to suspend an animal activity on behalf of the IACUC.

50
Q

When reporting an IACUC suspension of an animal activity, the IACUC should:
A. Limit disclosure of the facts to the absolute minimum necessary to prevent institutional embarrassment.
B. Report the suspension as soon as possible to the regulatory authorities.
C. Notify regulatory authorities no later than one year after the suspension.
D. Notify regulatory authorities no earlier than 3 months after a suspension to ensure that a complete investigation has occurred.

A

B. Report the suspension as soon as possible to the regulatory authorities.

51
Q

Which of the following statements regarding the process of polling IACUC members via email is true?
A. Polling via email can be used to achieve a quorum if the IACUC does not have a quorum during a convened meeting.
B. Polling via email can be used to obtain IACUC suspension of an animal activity out of compliance.
C. Polling via email can be used to obtain IACUC approval of a protocol during a convened meeting.
D. Polling via email can be used to allow the IACUC members to call for full committee review when using the designated reviewer system.

A

D. Polling via email can be used to allow the IACUC members to call for full committee review when using the designated reviewer system.

52
Q

Which of the following statements about the use of “alternate” IACUC members is false?
A. Alternates should receive IACUC training or orientation like regular IACUC members.
B. Alternate members must be designated in advance and not simply as a matter of convenience on short notice.
C. Alternate members may vote on an issue even when the regular member is present and votes on the same issue.
D. Alternate members would be expected to vote their conscience rather than simply representing the views of the regular member.

A

C. Alternate members may vote on an issue even when the regular member is present and votes on the same issue.

53
Q

Which of these IACUC protocol review outcomes are recognized in the USDA Animal Welfare Act Regulations and PHS Policy?
A. Approve, conditional approval, and approval pending modifications.
B. Approve, require modifications in (to secure approval), and deferred approval.
C. Approve, require modifications in (to secure approval), and withhold approval.
D. Approve, disapprove, and probationary approval.

A

C. Approve, require modifications in (to secure approval), and withhold approval.

54
Q

Although opinions vary about the level of detail needed in IACUC minutes, a typical standard is that IACUC minutes:
A. Should provide as little information as possible to prevent outside observers from understanding how the IACUC operates.
B. Should allow an outside observer to verify that deliberations occurred and understand the outcomes of those deliberations.
C. Must be no longer than three pages to satisfy federal paperwork reduction regulations.
D. Must include an actual transcript of all conversations that occurred at the meeting, as a minimum.

A

B. Should allow an outside observer to verify that deliberations occurred and understand the outcomes of those deliberations.

55
Q

When conducting the facilities inspection portion of the semi-annual evaluation in compliance with both the USDA Animal Welfare Act Regulations and PHS Policy, the IACUC must include:
A. All areas housing animals for more than 24 hours, and laboratories where animal procedures are performed with the exception of laboratories performing only non-survival surgical procedures.
B. All areas housing animals for more than 12 hours, and all investigator laboratory and study areas where animal procedures are performed.
C. All areas housing animals for more than 24 hours, and all investigator laboratory and study areas where animal procedures are performed.
D. All areas housing animals for more than 12 hours, and laboratories where animal procedures are performed with the exception of laboratories performing only non-survival surgical procedures.

A

D. All areas housing animals for more than 12 hours, and laboratories where animal procedures are performed with the exception of laboratories performing only non-survival surgical procedures.

56
Q

To comply with the USDA Animal Welfare Act Regulations, what is the proper IACUC course of action to follow if a significant deficiency is not corrected according to the plan set forth in the IACUC semi-annual evaluation report?
A. Report the situation through the IO to USDA within 6 months.
B. Report the situation through the IO to USDA within 3 months.
C. Report the situation through the IO to USDA within 30 business days.
D. Report the situation through the IO to USDA within 15 business days.

A

D. Report the situation through the IO to USDA within 15 business days.

57
Q

Which of these statements is true concerning the USDA Animal Welfare Act?
A. The USDA passed the Animal Welfare Act, and Congress has released regulations to enforce it.
B. The USDA stands for United States Department of Assessments.
C. The USDA is responsible for enforcing the Animal Withholding Action Act passed by Congress.
D. The Animal Welfare Act regulations take precedence over guidelines produced by the Public Health Service, Department of Veterans Affairs, and other government agencies.

A

D. The Animal Welfare Act regulations take precedence over guidelines produced by the Public Health Service, Department of Veterans Affairs, and other government agencies.

58
Q

Which of the following is not an example of replacement?
A. The use of cell culture instead of animals to grow immortal cell lines.
B. The use of a kit to assay hormone levels instead of a bioassay involving animals.
C. The use of a new analgesic that provides better postoperative pain relief.
D. The use of computer modeling software to replace the use of animals in pharmacologic studies.

A

C. The use of a new analgesic that provides better postoperative pain relief.

59
Q

Which of the following is not an example of reduction?
A. The use of a new anesthetic that provides better induction and a shorter recovery period.
B. The shared use of tissues by more than one investigator to minimize animal use.
C. The use of improved assays that provide better data precision so that fewer animals are needed per group.
D. The use of common control groups during simultaneous experiments to limit the number of control animals needed.

A

A. The use of a new anesthetic that provides better induction and a shorter recovery period.

60
Q

Which of the following is not an example of refinement?
A. The use of newer surgical techniques that result in less tissue trauma.
B. The use of a new analgesic that provides better postoperative pain relief.
C. The use of computer modeling software to substitute for animal experiments.
D. The use of a new bleeding technique that causes less pain and distress.

A

C. The use of computer modeling software to substitute for animal experiments.

61
Q

What is required, of the IACUC, by the USDA AWA Regulations regarding alternatives?
A. Ensure that the limit on animal use assigned to the institution by the USDA is not exceeded more than once every three years.
B. Reduce animal usage by at least 10% per year over a five-year period.
C. Reduce animal usage by at least 25% over a five-year period.
D. Ensure that the principal investigator has considered alternatives to painful or distressing procedures, and review a written assurance that alternatives are not available.

A

D. Ensure that the principal investigator has considered alternatives to painful or distressing procedures, and review a written assurance that alternatives are not available.

62
Q

What is the basis for the pain/distress classification system used by most institutions?
A. AAALAC pain/distress categories.
B. PHS pain/distress categories.
C. USDA pain/distress categories.
D. Guide pain/distress categories.

A

C. USDA pain/distress categories.

63
Q

Which of the following activities would disqualify an animal from USDA category B?
A. Blood collection.
B. Being placed into new caging.
C. Breeding.
D. Being observed during quarantine.

A

A. Blood collection.

64
Q

Which of the following activities would disqualify an animal from USDA category D?
A. Retroorbital blood collection from a mouse performed under anesthesia.
B. Collecting tail snips from adult rodents for genotyping under local or general anesthesia.
C. Surgery performed under anesthesia.
D. Studies in which animals are allowed to die without pain relief.

A

D. Studies in which animals are allowed to die without pain relief.

65
Q

An investigator wishes to use animals in an experiment that involves category B, C, and D activities performed on the same animal. How should the animal be categorized?
A. Categories B, C, and D.
B. Category B.
C. Category C.
D. Category D.

A

D. Category D.

66
Q

Which of the following activities would place an animal in category E?
A. Lethal dose experiments in which animals are allowed to die without intervention.
B. Observation studies of normal primate behavior.
C. Blood collection from a superficial vessel of a dog.
D. Major surgery in which anesthetics and postoperative analgesics are administered.

A

A. Lethal dose experiments in which animals are allowed to die without intervention.

67
Q

All personnel performing animal procedures must be properly trained to do so when?
A. By the end of the experiments.
B. Before any procedures are performed.
C. Before any procedures are performed unless they have doctoral level or medical degrees.
D. Before any procedures are performed unless they receive a waiver from their supervisor.

A

B. Before any procedures are performed.

68
Q

Which statement about the Occupational Health and Safety Program is false?
A. You should enroll in the local Occupational Health and Safety Program before you begin your work with laboratory animals.
B. Typical services include rabies immunizations, TB testing, and tetanus immunizations.
C. You may not decline medical treatments provided as part of the Occupational Health and Safety Program.
D. Each institution must have an Occupational Health and Safety Program for personnel who have significant contact with laboratory animals.

A

C. You may not decline medical treatments provided as part of the Occupational Health and Safety Program.

69
Q

Which of the following is true of the dog exercise program mandated by the USDA Animal Welfare Act regulations?
A. Dogs must be provided additional exercise regardless of the floor area of the cage.
B. The IACUC can exempt an animal for scientific reasons.
C. The veterinarian cannot exempt an animal, even for medical reasons.
D. The veterinarian can exempt an animal for scientific reasons.

A

B. The IACUC can exempt an animal for scientific reasons.

70
Q

Which of the following is false concerning prolonged restraint of animals?
A. The restraint method used should be the least restrictive possible that will allow achievement of experimental objectives.
B. It can be justified as a convenience for the research staff.
C. The period of restraint should be the minimum required to achieve experimental objectives.
D. It should not be considered a normal method of housing.

A

B. It can be justified as a convenience for the research staff.

71
Q

Who are the two primary oversight bodies that administer the regulations for animal research?
A. USDA/APHIS and NIH/OLAW
B. USDA/APHIS and The Guide
C. NIH/OLAW and PHS
D. PHS and The Guide

A

A. USDA/APHIS and NIH/OLAW

72
Q

AWR 9 CFR 1.1 (Definitions 2023) define an animal as?
A. Any live dog, cat, nonhuman primate, guinea pig, hamster, rabbit, or any other warm-blooded animal, which is being used, or is intended for use for research, teaching, testing, experimentation, or exhibition purposes, or as a pet.
B. Any live or dead bird, rat, mice or livestock.
C. Any live or dead dog, cat, nonhuman primate, guinea pig, hamster, rabbit, or any other warm-blooded animal, which is being used, or is intended for use for research, teaching, testing, experimentation, or exhibition purposes, or as a pet.
D. Any warm-blooded species used in research.

A

C. Any live or dead dog, cat, nonhuman primate, guinea pig, hamster, rabbit, or any other warm-blooded animal, which is being used, or is intended for use for research, teaching, testing,

73
Q

How is the AWA enforced by?
A. PHS OLAW
B. USDA APHIS
C. The Guide
D. DoD

A

B. USDA APHIS

74
Q

What does Health Research Extension Act (HREA) provides…
A. Help with The Guide.
B. Mandate for USDA and established provisions for the use of animals.
C. Mandate for USDA and established provisions for the use of animals in biomedical and behavior research.
D. Mandate for the PHS Policy and established provisions for the use of animals in biomedical and behavior research.

A

D. Mandate for the PHS Policy and established provisions for the use of animals in biomedical and behavior research.

75
Q

OLAW 2015b

A

The organization and appointment of the IACUC, IACUC responsibilities, appropriate pre-surgical and post-surgical vet care, appropriate use of anesthetics, tranquilizers, analgesics, and paralytics, and appropriate methods of euthanaisa.

76
Q
A