CP - Transfusion Medicine Flashcards

1
Q

Storage preparation of FFP

Validity

A

-18*C within 8 hours

Stored for 1 year

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2
Q

Temp storage of FFP for 7 years

A

-65*C

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3
Q

When FFP is stored what temp will it be stored and used within 24 hours

A

1-6*C

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4
Q

When FFP is not used, what is the preparation to maintain for 5 days

A

Factor 5 and 8

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5
Q

Cryoprecipitate is a cold precipitated concentration of _____________

A

Factor 8

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6
Q

Indications for Cryoprecipitate

A

Treatment of Hemophilia A
Source fo Fibrinogen
Transfusion or congenital fibrinogen deficiency

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7
Q

Platelet concentrate must contain at least _______amt of platelets

A

5.5x10^10 Platelet/unit

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8
Q

Platelet concentrate should be stored in what temp if stored for 5 days

A

20-24*C

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9
Q

Platelet concentrate is _____ to _____ mL of plasma

A

30-50 mL

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10
Q

Platelet Concentrate when thawed should be transfused within how many hours

A

4 hours

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11
Q

Indication for Platelet Concentrate

A

Bleeding (DIC), Thrombocytopenia
Abnormal Platelet Count
Propylaxis under 5-10K/ul

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12
Q

Steroids are given prior to procedure and exposed to Hydroxyethyl starch

A

Granulocyte Concentrate

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13
Q

Storage of Granulocyte Concentrate within 24 hours

A

20-24*C

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14
Q

True or False: Granulocyte Concentrate transfusion doesn’t need to be ABO & Rh, Crossmatch compatible

A

FALSE

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15
Q

Cyroprotective Agent that is a Large molecule form of a shell around the cell
Prevents loss of water and subsequent dehydration

A

Non Penetrating - Hydroxyethyl Starch

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16
Q

Cryoprotective Agent that has a small molecule that cross cell membrane
Prevents wate from migrating outward
Extracellular ice formation - prevents intracellular dehydration

A

Penetrating - Glycerol

17
Q
High or Low Glycerol:
Increased Cryoprotection
Slow uncontrolled freezing process
Require larger volume of wash solution (Stored at -80*C)
Most widely used
A

High Glycerol (40% weight per volume)

18
Q
High or Low Glycerol:
Minimal Cyoprotection
Very Rapid, more controlled freezing
Liquid nitrogen
Routinely use (stored at -120* C)
A

Low Glycerol

19
Q

Treatment for Delayed Hemolytic reactions

A

IVIG

20
Q

Dyspnea, hypoxemia, tachycardia, fever, hypotension and cyanosis - during or within hours of transfusion

A

Transfusion related acute lung injury (TRALI)

21
Q

What can you see in a Radiograph of TRALI

A

Generalized pattern of Pulmonary Edema