Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

SECOND YEAR > Autonomic Drugs > Flashcards

Autonomic Drugs Flashcards

1
Q

Drugs that act on receptors activated by Ach (muscarinic and nicotinic)

A

Cholinergic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drugs that act on receptors activated by NE or E

A

Adrenergic drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Cholinergic agonists that look and act like Ach

A

Direct Acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Cholinergic agonists that increase the amount of Ach

A

Indirect Acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Drug used for diagnosis of myasthenia gravis

A

Edrophonium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Drug of choice for myasthenia gravis

A

Neostigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drug for maintenance of myasthenia gravis

A

Pyridostigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Site of action of ganglionic blockers (cholinergic antagonist)

A

Nicotinic receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Site of action of antimuscarinic drugs (cholinergic antagonist)

A

Muscarinic receptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Site of action of neuromuscular blockers (cholinergic antagonist)

A

Nicotic receptor on striated muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Atropine is a ganglionic blocker. True or false?

A

False.

It’s an antimuscarinic drug.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The three antimuscarinic drugs used to TREAT the manifestations of Parkinson’s disease

A

Benztropine
Trihexyphenidyl
Biperiden

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Why are ganglion-blocking drugs not commonly given?

A

They also stimulate the sympathetic so they have so many side effects.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Representative of ganglion-blocking drugs

A

Trimetaphan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antimuscarinic drug that is important in producing complete skeletal muscle relaxation in surgery

A

Neuromuscular blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Prototype of non-depolarizing NM blockers

A

Tubocurarine - competitive blocking at NMJ leading to flaccid paralysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Why is succinylcholine used as a muscle relaxant when it’s a nicotinic agonist?

A

Succinylcholine is an Ach mimic. It will stimulate muscle contraction. The muscle contraction will be sustained, leading to muscle weakness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Antimuscarinic drugs that increase cholinesterase

A

Cholinesterase regenerators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Mechanism of organophosphate poisoning

A

Organophosphates block ChE leading to Ach excess.

20
Q

Antidote of choice for organophosphate poisoning

A

Pralidoxime

21
Q

Mechanism of cholinesterase regenerator against organophosphate poisoning

A

The oxime group in ChE bind to the phosphorous part of organophosphate.
(Suicide inhibitor)

22
Q

Smooth muscle contraction?

Alpha1
Alpha2
Beta1
Beta 2

A

Alpha 1 - keyword: CONTRACTION

23
Q

Increased force of contraction of heart?

Alpha1
Alpha2
Beta1
Beta 2

A

Alpha 1 - keyword: CONTRACTION

24
Q

Platelet aggregation

Alpha1
Alpha2
Beta1
Beta 2

A

Alpha2

25
Q

Inhibits transmitter release?

Alpha1
Alpha2
Beta1
Beta 2

A

Alpha2

26
Q

Inhibits lipolysis?

Alpha1
Alpha2
Beta1
Beta 2

A

Alpha2

27
Q

Heart, juxtglomerular apparatus

Alpha1
Alpha2
Beta1
Beta 2

A

Beta1

28
Q

Respiratory, uterine, vascular smooth muscle

Alpha1
Alpha2
Beta1
Beta 2

A

Beta2

29
Q

Promotes potassium uptake?

Alpha1
Alpha2
Beta1
Beta 2

A

Beta2

30
Q

Relaxes detrusor muscle

Beta1
Beta2
Beta3
D1
D2
A

Beta3

31
Q

Activates lipolysis

Beta1
Beta2
Beta3
D1
D2
A

Beta3

32
Q

Modulates transmitter release

Beta1
Beta2
Beta3
D1
D2
A

D2

33
Q

Functions for negative feedback

Alpha1
Alpha2
Beta1
Beta2

A

Alpha2

34
Q

Indirect acting adrenergic agonist that is a precursor for tyrosine

A

Tyramine

35
Q

Beta blockers that have alpha-blocking properties

A

Carvedilol and Labetalol

36
Q

Beta blocker that has the longest half-life

A

Nadolol

37
Q

Beta blocker that has the shortest half life

A

Esmolol

38
Q

Beta blocker that has the highest BA

A

Penbutolol

39
Q

Beta blockers with some beta agonistic properties

A

Acetabulol and Pindolol

40
Q

Most common use of beta blockers

A

Hypertension and chest pain

41
Q

Action of acetylcholine

Muscarinic
Nicotinic
Both

A

Both

42
Q

Action of bethanecol

Muscarinic
Nicotinic
Both

A

Muscarinic

43
Q

Action of carbachol

Muscarinic
Nicotinic
Both

A

Both

44
Q

Action of pilocarpine

Muscarinic
Nicotinic
Both

A

Muscarinic

45
Q

Action of nicotine

Muscarinic
Nicotinic
Both

A

Nicotinic

46
Q

Why give adreneceptor agonist to an ADHD patient?

A

ADHD patients only have attention deficit. They are not hypermetabolic. A stimulant will increase attention span.

47
Q

Why do the effects of amphetamine last for long?

A

They are resistant to MAO and COMT

SECOND YEAR (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions