Cp Flashcards

1
Q

comprises a set of functions that promote the safe, effective and economic use of medicines for individual patients.

A

Clinical pharmacy

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2
Q

has allowed pharmacists to shift from a product-oriented role towards direct engagement with patients and the problems they encounter with medicines.

A

• The emergence of clinical pharmacy

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3
Q

• is generally an essential component of pharmaceutical care.

A

The practice of clinical pharmacy

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4
Q

is a co-operative, patient-centred system for achieving specific and positive patient outcomes from the responsible provision of medicines.

A

• Pharmaceutical care

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5
Q

• The three key elements of the care process are

A

patient assessment, determining the care plan and evaluating the outcome.

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6
Q

• The ability to consult with_______is a key process in the delivery of pharmaceutical care and requires regular review and development regardless
of experience.

A

patients

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7
Q

has been incorporated into a professional development framework that can be used to enhance skills and knowledge.

A

clinical pharmacy process

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8
Q

, unlike the discipline of pharmacy, is a comparatively recent and variably implemented form of prac- tice. It encourages pharmacists and support staff to shift their focus from a solely product-oriented role towards more direct engagement with patients and the problems they encoun- ter with medicines.

A

Clinical pharmacy

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9
Q

as a form of practice has been attributed to the poor medicines control systems that existed in hospitals during the early 1960s (Cousins and Luscombe, 1995).

A

The emergence of clinical pharmacy

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10
Q

In the_______, the approach was to adopt unit dose dispens- ing and pursue decentralisation of pharmacy services. In the_______the unification of the prescription and the administra- tion record meant this document needed to remain on the hospital ward and required the pharmacist to visit the ward to order medicines

A

USA
UK

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11
Q

Clinical pharmacy thereby emerged from the presence of pharmacists in these patient areas and their inter- est in promoting safer medicines use. This was initially termed _______but participation in medical ward rounds in the late 1970s signalled the transition to clinical pharmacy.

A

ward pharmacy

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12
Q

Medication safety may have been the spur but clinical phar-macy in the ______grew because of its ability to promote cost- effective medicines used in hospitals. This role was recognised by the UK government, which, in ________endorsed the imple- mentation of clinical pharmacy services to secure value for money from medicines.

A

1980s
1988

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13
Q

were necessary to aggregate large amounts of data in a reliable manner and many of these drew upon the eight steps (Table 1.1) of the drug use process (DUP) indicators (Hutchinson et al., 1986).

A

Coding systems

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14
Q

Drug use process indicators

A

Need for a drug
Select drug
Select regimen
Provide drug
Drug administration
Monitor drug therapy
Counsel patient
Evaluate effectiveness

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15
Q

Ensure there is an appropriate indication for each drug and that all medical problems are addressed therapeutically

A

need for a drug

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16
Q

Select and recommend the most appropriate drug based upon the ability to reach therapeutic goals, with consideration of patient variables, formulary status and cost of therapy

A

Select drug

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17
Q

Select the most appropriate drug regimen for accomplishing the desired therapeutic goals at the least cost without diminishing effectiveness or causing toxicity

A

Select drug regimen

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18
Q

Facilitate the dispensing and supply process so that drugs are accurately prepared, dispensed in ready-to- administer form and delivered to the patient on a timely basis

A

Provide drug

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19
Q

Ensure that appropriate devices and techniques are used for drug administration

A

Drug administration

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20
Q

for effectiveness or adverse effects in order to determine whether to maintain, modify or discontinue

A

Monitor drug therapy

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21
Q

Counsel and educate the patient or caregiver about the patient’s therapy to ensure proper use of medicines

A

COUNSEL PATIENTS

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22
Q

Evaluate the effectiveness of the patient’s drug therapy by reviewing all the previous steps of the drug use process and taking appropriate steps to ensure that the therapeutic goals are achieved

A

Evaluate effectiveness

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23
Q

comprises a set of functions that promote the safe, effective and economic use of medicines for individual patients.

A

Clinical pharmacy

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24
Q

requires the application of specific knowledge of pharmacology, pharmacokinetics, pharmaceutics and therapeutics to patient care select drug select and recommend the most appropriate drug based upon the ability to reach therapeutic goals, with consideration of patient variables, formulary status and cost of therapy select regimen select the most appropriate drug regimen for accomplishing the desired
therapeutic goals at the least cost without diminishing effectiveness or causing toxicity

A

Clinical pharmacy process

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25
Q

is a co-operative, patient-centred system for achieving specific and positive patient outcomes from the responsible provision of medicines. The practice of clinical pharmacy is an essential component in the delivery of pharmaceutical care

A

Pharmaceutical care

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26
Q

encompasses the way in which medicines are selected, procured, delivered, prescribed, administered and reviewed to optimise the contribution that medicines make to producing informed and desired outcomes of patient care

A

medicines management

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27
Q

is dependent on the practice of clinical pharmacy but the key feature of care is that the practitioner takes responsibility for a patient’s drug- related needs and is held accountable for that commitment.

A

delivery of pharmaceutical care

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28
Q

has enabled pharmaceutical care to permeate community pharmacy, particularly in Europe, in a way that clinical pharmacy and its bedside connotations did not.

A

avoidance of factionalism

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29
Q

Box 1.1 Categories of medication-related problems

A

Untreated indication
Treatment without indication
Too little drug
Too much drug
improper drug selection
non-compliance
Drug interaction
adverse drug reaction

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30
Q

are associated with significant morbidity and mortality. Preventable medication-related hospital admissions in the USA have a prevalence of 4.3%, indicating that gains in public health from improved medi- cines management would be sizeable (Winterstein et al., 2002).

A

MRPs

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31
Q

, defined as pre- ventable events that may cause or lead to inappropriate medi- cines use or harm, in NHS hospitals has been estimated to lie between £200 and £400 million per year. To this should be added the costs arising from litigation (DH, 2004).

A

The direct cost of medication errors

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32
Q

Recognition that many patients either fail to benefit or experience unwanted effects from their medicines has elicited two types of response from the pharmacy profession.

A

The first response has been to put in place, and make use of, a range of post- graduate initiatives and programmes to meet the develop- mental needs of pharmacists working in clinical settings.

The second has been the re-engineering of pharmaceutical services to introduce schemes for medicines management at an organisational level.

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33
Q

has served to improve the knowledge of clinical pharmacists but fully achieving the goals of pharmaceutical care has proved more challeng- ing.

A

Structured postgraduate education

34
Q

is predicated on a patient-centred approach to identifying, preventing or resolving medicine- related problems.

A

Pharmaceutical care

35
Q

has shown that self-management is promoted when patients more fully participate in the goal- setting and planning aspects of their care (

A

Research in chronic diseases

36
Q

In community pharmacy, one approach to help patients used their medicines more effectively is

A

medicines use review (MUR).

37
Q

Two goals of MUR are to

A

improve the adherence of patients to prescribed medicines

to reduce medicines wastage.

38
Q

Key elements of the care process

A

Assessment
Care plan
Evaluation

39
Q

The main goal is to establish a full medication history and highlight actual and potential drug-related problems

A

assessment

40
Q

This should clearly state the goals to optimise care and the responsibilities of both the pharmacist
and the patient in attaining the stated goals

A

Care plan

41
Q

This reviews progress against the stated patient outcomes

A

evaluation

42
Q

The ability of a pharmacist to_______effectively is fundamental to pharmaceutical care and this includes establishing a platform for achieving adherence/ concordance.

A

consult

43
Q

provide the pharmacist with a rigid structure to use when questioning patients about their symptoms but, although useful, serve to make the symptom or disease the focus of the consultation rather than the patient.

A

WWHAM, AS METTHOD and ENCORE

44
Q

Box 1.2 Mnemonics used in the pharmacy consultation process
WWHAM

A

Who is it for?
What are the symptoms?
How long has it been going on?
Action taken?
Medicines taken?

45
Q

AS METTHOD

A

Age of the patient?
Self or for someone else?
Medicines being taken?
Exactly what do you mean (by the symptom)?
Time and duration of the symptom
Taken any action (medicine or seen the doctor)?
History of any disease?
Other symptoms?
Doing anything to alleviate or worsen the symptom?

46
Q

ENCORE

A

Evaluate the symptom, its onset, recurrence and duration.
No medication is always an option.
Care when dealing with specific patient groups, notably the elderly, the young, nursing mothers, pregnant women, those receiving specific medication such as methotrexate and
anticoagulants, and those with particular disease, for example, renal impairment.

Observe the patient for signs of systemic disturbance and ask about presence of fever, loss of weight and any accompanying physiological disturbance.

Refer when in doubt.

Explain any course of action recommended.

47
Q

Active listening
Appropriate use of open and closed questions.
Respect patient
Avoid jargon
Demonstrate empathy
Deal sensitively with potentially embarrassing or sensitive issues

A

Box 1.3 Consultation behaviours

48
Q

Pharmaceutical consultation process

A

Introduction
Data collection and problem identification
Actions and solutions
Closure

49
Q

Building a therapeutic relationship

A

Introduction

50
Q

Identifying the patient’s medication-related needs

A

Data collection and problem identification

51
Q

Establishing an acceptable
management plan with the patient

A

Actions and solutions

52
Q

Negotiating safety netting strategies with the patient

A

Closure

53
Q

Invites patient to discuss medication or health-related issue
Discusses structure and purpose of consultation
Negotiates shared agenda

A

Introduction

54
Q

Takes a full medication history
Establishes patient’s understanding of their illness
Establishes patient’s understanding of the prescribed treatment Identifies and prioritises patient’s pharmaceutical problems

A

Data collection and problem identification

55
Q

Involves patient in designing management plan
Tailors information to address patient’s perception of illness and treatment

Checks patient’s understanding
Refers appropriately

A

Actions and solutions

56
Q

Do i know more now about the patient?
Was i curious?
Did i really listen?
Did i find out what really mattered to them?
Did i explore their beliefs and expectations?
Did i identify the patient’s main medication-related problems? Did i use their thoughts when i started explaining?
Did i share the treatment options with them? Did i help my patient to reach a decision? Did i check that they understood what i said? Did we agree?
Was i friendly?

A

Key postconsultation questions

57
Q

The_________ role, therefore, is often one of providing information to the independent prescriber on the expected benefits and risks of drug therapy by evaluating both the evidence base and individ- ual patient factors.

A

pharmacist’s

58
Q

also draw on these concepts as they become more involved in prescribing and adjusting therapy for patients under their care.

A

Pharmacists

59
Q

Factor of relvant patient details

A

Age
Gender
Ethnic or religious background
Social history
Presenting complaint
Previous medical history
Working diagnosis
Laboratory or physical findings

60
Q

The very young and the very old are most at risk of medication-related problems. A patient’s age may indicate their likely ability to metabolise and excrete medicines and have implications for step 2 of the drug use process

A

Age

61
Q

This may alter the choice of the therapy for certain indications. It may also prompt consideration of the potential for pregnancy or breast feeding

A

Gender

62
Q

Racially determined predispositions to intolerance or ineffectiveness should be considered with certain classes of medicines, for example, ACE inhibitors in Afro-Caribbean people. Formulations may be problematic for other groups, for example, those based on blood products for Jehovah’s Witnesses or porcine-derived products for Jewish patients

A

Ethnic or religious background

63
Q

This may impact on ability to manage medicines and influence pharmaceutical care needs, for example, living alone or in a care home or availability of nursing, social or informal carers

A

Social history

64
Q

Symptoms the patient describes and the signs identified by the doctor on examination. Pharmacists should consider whether these might be attributable to the adverse effects of prescribed or purchased medicines

A

Presenting complaint

65
Q

This should enable the pharmacist to identify the classes of medicines that would be anticipated on the prescription based on current evidence

A

Working diagnosis

66
Q

Understanding the patient’s other medical conditions and their history helps ensure that management of the current problem does not compromise a prior condition and guides the selection of appropriate therapy by identifying potential contraindications

A

Previous medical history

67
Q

The focus should be on findings that may affect therapy, such as
renal function
liver function
full blood count
blood pressure
cardiac rhythm
Results may convey a need for dosage adjustment or presence of an adverse reaction

A

Laboratory or physical findings

68
Q

is the part of a pharmaceutical consul- tation that identifies and documents allergies or other serious adverse medication events, as well as information about how medicines are taken currently and have been taken in the past. It is the starting point for medicines reconciliation and medi- cation review.
Obtaining accurate and complete medication histories has been shown to have a positive effect on patient care and phar- macists have demonstrated that they can compile such histo- ries with a high degree of precision and reliability as part of medicines reconciliation.

A

A medication history

69
Q

is the part of a pharmaceutical consul- tation that identifies and documents allergies or other serious adverse medication events, as well as information about how medicines are taken currently and have been taken in the past. It is the starting point for medicines reconciliation and medi- cation review.
Obtaining accurate and complete medication histories has been shown to have a positive effect on patient care and phar- macists have demonstrated that they can compile such histo- ries with a high degree of precision and reliability as part of medicines reconciliation.

A

A medication history

70
Q

may occur when a medicine has the potential to make a pre-existing condition worse. Older people are particularly vulnerable due to the co-existence of several chronic diseases and exposure to polypharmacy. Prevention of drug-disease interactions requires an understanding of the pharmacodynamic properties of medicines and an apprecia- tion of their contraindications.

A

drug-disease interaction

71
Q

may affect the action of other medicines in a number of ways. Those with similar mechanisms of action may show an enhanced effect if used together whilst those with opposing actions may reduce each other’s effectiveness.

A

Medicines

72
Q

of one medicine can be affected by a second that acts as an inducer or inhibitor of the cytochrome P450 enzyme system.

A

Metabolism

73
Q

has extensive capacity for drug metabolism, even when damaged. Nevertheless, the degree of hepatic impair- ment should be assessed from liver function tests and related to potential changes in drug metabolism. This is particularly important for medicines that require activation by the liver (pro-drugs) or those whose main route of elimination is trans- formation into water-soluble metabolites.

A

liver

74
Q

Giving medicines via the____route is the preferred method of administration. Parenteral routes carry significantly more risks, including infection associated with vascular access. This route, however, may be necessary when no oral formulation exists or when the oral access is either impossible or inappro- priate because of the patient’s condition.

A

oral

75
Q

Pharmaceutical considerations in the administration of medicines

A

Dose
Route
Dosage form
Documentation
Devices

76
Q

Is the dose appropriate, including adjustments for particular routes or formulations? Examples: differences in dose between intravenous and oral metronidazole, intramuscular and oral chlorpromazine, and digoxin tablets compared with the elixir

A

Dose

77
Q

Is the prescribed route available (is the patient nil by mouth?) and appropriate for the patient?
Examples: unnecessary prescription of an
intravenous medicine when the patient can swallow, or the use of a solid dosage form when the patient has dysphagia

A

Route

78
Q

Is the medicine available in a suitable form for administration via the prescribed route?

A

Dosage form

79
Q

Documentation Is documentation complete? Do nurses or

A

Documentation

80
Q

carers require specific information to administer the medicine safely?
Examples: appropriateness of crushing tablets for administration via nasogastric tubes, dilution requirements for medicines given parenterally, rates of administration and compatibilities in parenteral solutions (including syringe drivers)
Are devices required, such as spacers for inhalers?

A

Devices