Cough (Resp. 3) Flashcards

1
Q

Give 3 examples of the following pneumonias:

  • CAP
  • HAP
  • Atypical
A
  • CAP: Strep. Pneumoniae, Haemophillus influenza B, moraxella catarrhalis
  • HAP: Staph aureus, pseudomonas aeruginosa, Klebsiella
  • Atypical: Mycoplasma pneumonia, legionella pneumophila (A/C), chlamydia psittaci (pet birds)
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2
Q

What is difference between X-ray of bronchopneumonia and lobar pneumonia.

A
  • Lobar is homogenous broncho is patchy.
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3
Q

Which scoring system is used for CAP? What score is needed for inpatient stay?

A
  • CURB 65

- 3+ is inpatient stay.

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4
Q

Which antibiotics are used to treat following pneumonias:

  • CAP
  • HAP
  • Atypical
  • Aspiration
A
  • CAP: Amoxicillin (co-amoxiclav if severe)
  • HAP: Staph: Flucloxacillin + gentamicin. MRSA: Vancomycin.
  • Atypical: Clarithromycin
  • Aspiration (anaerobes from gut flora): Metronidazole.

In general give amoxicillin and clarithromycin.

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5
Q

Give common pathogen of lung abscess. Give 3 signs.

A
  • Staph aureus

- Swinging fevers, persistent pneumonia, foul-smelling sputum.

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6
Q

Give 6 systemic complications of TB.

A
  • Pneumonia, pleural effusion
  • Meningitis
  • Erythema Nodosum and clubbing.
  • Pott’s disease
  • Epididymo-orchitis
  • Addison’s disease, renal failure
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7
Q
  • Which microscopy stain is used to investigate TB and what is visualised?
  • What is found in lymph node biopsy?
  • Which blood test screen is used?
A
  • Ziehl-Neelsen stain
  • Visualisation of acid-
    fast bacilli.
  • LN biopsy: caseating granuloma.
  • IGRA: Interferon gamma release assay.
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8
Q

Give 3 signs of TB on CXR.

Give 1 sign of Miliary TB on CXR.

A
  • Consolidation- heterogenous (patchy)
  • Bi-hilar lymphadenopathy
  • Upper lobe scarring
  • Miliary TB: nodular shadowing. TB where it has spread to lymph nodes.
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9
Q

Give a definition of bronchiectasis.

Give 3 congenital causes of bronchiectasis.

Give 4 acquired causes of bronchiectasis.

A
  • Chronic permanent dilation of airways alongside increased mucus production.
  • Cystic fibrosis
  • Primary ciliary dyskinesia- Kartagener’s syndrome
  • Young’s syndrome.
  • Pneumonia
  • TB
  • Measles
  • Pertussis
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10
Q

Give an inspection and an auscultation finding of bronchiectasis.

A
  • Clubbing

- Bibasal crackles

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11
Q

Give 4 respiratory causes of clubbing

Give 4 respiratory causes of bibasal crackles

A
  • Bronchiectasis (cystic fibrosis), lung cancer, TB, IPF

- Pulm. oedema, pneumonia, bronchiectasis, IPF

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12
Q

What is best investigation for bronchiectasis? What is classic sign in this investigation?
What is a test for cystic fibrosis?

A
  • High resolution CT Chest. Signet ring sign.

- Sweat test measures chloride concentration in sweat.

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13
Q

Give 4 pharmacological managements for bronchiectasis.

A
  • Inhaled salbutamol
  • Inhaled ABx- oral azithromycin
  • Influenza flu vaccine
  • IV ABx (acute)- levofloxacin if pseudomonas.
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14
Q

List 4 types of primary lung cancer.

A
  • Small cell: 15%- SIADH, ectopic ACTH.
    Non-small cell:
  • Adenocarcinoma: most common. Goblet cells, peripheral lung.
  • Squamous cell carcinoma. Squamous epithelial cells- PTH
  • Large cell carcinoma: epithelial cells.
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15
Q

Give 2 local invasion sites of lung cancer.

A
  • Nervous system: horner’s syndrome, left recurrent laryngeal nerve (causes bovine cough).
  • Superior vena cava- obstruction.
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16
Q

What are following results in lung cancer:

  • Ca2+
  • ALP
  • LFT
A
  • Ca2+ raised if bone mets or PTHrp
  • raised ALP- bone mets
  • Deranged LFTs if liver metastases.
17
Q

What are 4 stages of lung cancer

A
  1. Cancer only in lung
  2. Cancer in lung and near lymph nodes
    3a. Lung and LN same side of chest as origin
    3b. Lung and LN opposite side of chest or above clavicle
  3. Both lungs, area around lungs or distant organs.
18
Q

Give risk factor for mesothelioma.

Give auscultation sign of mesothelioma.

A
  • Asbestos exposure
    Sx of lung cancer.
  • Pleural friction rub on auscultation: like walking on fresh snow.
19
Q

Give 3 signs of mesothelioma on CXR/ CT

A
  • Pleural thickening
  • Pleural effusion
  • Pleural plaques due to asbestos.