cortisol Flashcards
2
Q
Actions of cortisol: increases…
A
• lipolysis: increase FFA. excess–> inc total cholesterol, decreased HDLs• glucose: promotes gluconeogenesis, inhibits uptake into muscle and fat• BP• protein catabolism–> more aa for gluconeogenesis
3
Q
Actions of cortisol: decreases…
A
• ADH, to increase water clearance• eosinophils
4
Q
What are the 3 gluconeogenic enzymes that cortisol upregulates?
A
- glucose-6-phosphatase2. fructose 1,6-bisphosphatase3. PEPCK: phosphoenol pyruvate carboxykinase
5
Q
non metabolic actions of cortisol….
A
• positive inotropic action on heart• increase serum calcium• increase GFR, renal blood flow, free water clearance• inhibit fibroblast proliferation and collagen formation• stimulates production of surfactant• inhibits immune function