cortisol Flashcards

2
Q

Actions of cortisol: increases…

A

• lipolysis: increase FFA. excess–> inc total cholesterol, decreased HDLs• glucose: promotes gluconeogenesis, inhibits uptake into muscle and fat• BP• protein catabolism–> more aa for gluconeogenesis

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3
Q

Actions of cortisol: decreases…

A

• ADH, to increase water clearance• eosinophils

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4
Q

What are the 3 gluconeogenic enzymes that cortisol upregulates?

A
  1. glucose-6-phosphatase2. fructose 1,6-bisphosphatase3. PEPCK: phosphoenol pyruvate carboxykinase
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5
Q

non metabolic actions of cortisol….

A

• positive inotropic action on heart• increase serum calcium• increase GFR, renal blood flow, free water clearance• inhibit fibroblast proliferation and collagen formation• stimulates production of surfactant• inhibits immune function

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