corticosteroids/meds to manage diabetes Flashcards
Too much inflammation after tapering off from corticosteroids would indicate what?
steroid dependant
This is a complex defence mechanism that includes major vasodilation, leukocyte attraction to the site, increased fluid (edema), heat, pain, redness, REEDA.
inflammatory response
What are the 3 main roles of prostaglandins?
Events leading to inflammation, production of pain and fever, blood clotting
If a patient is taking a medication that has a role in inhibiting prostaglandins, they are more at risk for increased clotting or increased bleeding.
increased bleeding
The main action of this medication is to inhibit prostaglandin action by blocking COX.-
NSAIDs
Which medication is a popular non-steroidal anti-inflammatory drug
ibuprofren
The properties of this medication include anti-inflammatory, antipyretic, and analgesic.
NSAIDS- ibuprofen
Overexpression side effects of this medication are GI- upset, Renal side effects, and bleeding.
ibuprofen
corticosteroids is an umbrella term that includes?
Glucocorticoids and mineralcorticoids
what is the order of the HPA axis to release corticosteroids?
hypothalamus–> anterior pituitary–>ACTH –> adrenal glands–> corticosteroids
Powerful metabolic effects/stress response, glucose metabolism, reduce inflammation, suppression of the immune system, influence sleep pattern and mood, decrease bone formation and increase bone breakdown, increase calcium excretion, and lipogenesis are the effects of which corticosteroid?
glucocorticoids (cortisol)
Retention of sodium and water, excretion of potassium; essential for the maintenance of fluid and electrolyte balance, blood pressure, and blood volume are the effect of which corticosteroids?-
mineralcorticoids- aldosterone
this medication (or class of) acts as an anti-inflammatory and immunosuppressant
corticosteroid (prednisone)
this medication has mainly glucocorticoid properties with minimal mineralocorticoid activity. Mostly used as an anti-inflammatory and modifies the immune response
corticosteroid- prednisone
Even though this medication has some benefits it also has many overexpression side effects including osteoporosis, insomnia, mood changes, weight gain, over-suppression of the immune system(infection), increased bleeding, GI upset, GI ulcers, skin breakdown, hypocalcemia, hyperglycemia/diabetes, hypertension, hypernatremia and hypokalemia
corticosteroid