Cortex and Hippocampus Flashcards

1
Q

Primary Cortex

A
  • unimodal

- serves a single behavioral function

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2
Q

Secondary Cortex

A
  • unimodal

- association for primary corticies

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3
Q

Tertiary Cortex

A
  • heteomodal

- integrates info from secondary corticies

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4
Q

Quaternary Cortex

A
  • heteromodal

- integrates info from tertiary cortices

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5
Q

Bottom Up Processing of Perception: Acetylcholine

A
  • acetylcholine

- cholinergic populations in N. basalis and pedunculopontine tegmental nucleus

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6
Q

Bottom Up Processing: Norepinephrine

A
  • noradrenergic cells of L. ceruleus have general functions which bear on aspects of attention, learning, and arousal
  • activity probably improves processing of salient events in diverse forebrain sites
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7
Q

Dorsolateral Prefrontal Cortex (DLPFC) Damage

A
  • unable to use intention (goals) to modulate attention (task at hand)
  • failure to switch attention appropriately = perseveration
  • undue requirement for environmental cues to accomplish task = environmental dependency
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8
Q

Anterior Cingulate and Motivation

A
  • the apathy syndrome
  • dec. goal directed behavior
  • dec. goal directed cognition
  • dec. emotional experience and responsiveness
  • abulia= lack of will
  • akinetic mutism
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9
Q

Orbitofrontal Cortex (VmOFC) Lesions

A
  • impairment in ability to estimate the risk/reward associated with certain behaviors
  • implies subconscious “gut feeling” about the implications of a given behavior
  • implies suppression of behaviors felt to be excessively risky, esp. in social situations
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10
Q

Prefontal Cortex Function

A
  • enhancement and inhibition of: sensory inputs, emotional control, motor control
  • short term modulation: modulation of effective connectivity
  • long term modulation: modulation of synaptic strengths
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11
Q

Hippocampus

A
  • critical for episodic memory
  • spatial memory, navigation, location
  • associative networks
  • integrates parallel streams of spatial and non spatial informtation: CA3
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12
Q

Hippocampus Schaeffer Collaterals

A

-CA3 -> CA1

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13
Q

Mossy Fibers

A

-dentate -> CA3

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14
Q

Perforant Path

A

-entorhinal -> dentate

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15
Q

CA3 Autoassociation

A

-CA3 -> CA3

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16
Q

Memory Consolidation

A

-reverse replay of sequences in the hippocampus during sleep

17
Q

Layers 1-3 Cortex

A
  • interoffice mail of cortex and outbox

- pyramidal cells

18
Q

Layers 4.1-4.3 Cortex

A
  • Inbox of cortex

- graule cells

19
Q

Layers 5 and 6 of Cortex

A

-Pyramidal Cells

20
Q

20% of cortical neurons are:

A

-inhibitory interneurons

21
Q

Feedback Cortex Mechanism

A
  • layers 2, 5, 6 -> lower layers 1, 5, 6
  • top down
  • predicted (habitual responses)
22
Q

Feedforward Cortex Mechanism

A
  • Layer 3 -> higher layer 4 -> 3
  • bottom up
  • observed responses to stimuli