Corrections 2 Flashcards
What is balanitis xerotica obliterans?
The male equivalent to lichen sclerosis in women
Complication of balanitis xerotica obliterans?
In an uncircumcised male, it can cause phimosis which is when the foreskin is too tight and can not be pulled back past the glans.
This is due to the scarring that occurs from BXO.
Bullous pemphigoid vs pemphigus vulgaris?
Mucosal involvement –> pemphigus vulgaris
No mucosal involvement –> bullous pemphigoid
What is the most common cause of nappy rash?
Irritant dermatitis –> due to irritant effect of urinary ammonia and faeces
What is lichen planus?
a skin disorder of unknown aetiology, most probably being immune-mediated.
Features of lichen planus?
1) itchy, papular rash most common on the palms, soles, genitalia and flexor surfaces of arms
2) rash often polygonal in shape, with a ‘white-lines’ pattern on the surface (Wickham’s striae)
3) Koebner phenomenon may be seen (new skin lesions appearing at the site of trauma)
4) oral involvement in around 50% of patients: typically a white-lace pattern on the buccal mucosa
5) nails: thinning of nail plate, longitudinal ridging
Mainstay of treatment of lichen planus?
Topical potent steroids
What can cause rusty-red pigmentation of the calves in venous insufficiency?
Haemosiderin deposition
What is the typical distribution of atopic eczema in infants?
Face & trunk
What is the typical distribution of atopic eczema in younger children?
Extensor surfaces
What is the typical distribution of atopic eczema in older children?
Flexor surfaces (typical)
What is a strong risk factor for singles?
HIV & other immunosuppressive conditions (e.g. steroids, chemotherapy)
What is shingles (AKA herpes zoster)?
An acute, unilateral, painful blistering rash caused by reactivation of the VZV
What are the most commonly affected dermatomes in shingles?
T1-L2
Features of shingles?
1) prodromal period
- burning over the affected dermatome
- pain
- fever, headache, lethargy
2) rash:
- initially erythematous, macular rash over the affected dermatome
- quickly becomes vesicular
- well demarcated by the dermatome
Mx of shingles?
1) analgesia: paracetamol & NSAIDs
2) antivirals e.g. aciclovir
Wat is a key benefit of prescribing antivirals in shingles?
Reduced incidence of post-herpetic neuralgia
How long are people with shingles infective?
they are infectious until the vesicles have crusted over, usually 5-7 days following onset
What is the most common complication of shingles?
Who is this more common in?
Post herpetic neuralgia
More common in older patients
give 3 complications of shingles
1) post-herpetic neuralgia
2) herpes zoster ophthalmicus
3) herpes zoster oticus (Ramsay Hunt syndrome)
What are some exacerbating factors for psoriasis?
1) trauma
2) alcohol
3) drugs e.g. beta blockers, lithium, antimalarials, NSAIDs & ACEi
4) withdrawal of systemic steroids
What infection may trigger guttate psoriasis?
Streptococcal
What is a herald patch?
Pityriasis rosea is a rash that often begins as an oval spot on the face, chest, abdomen or back.
This is called a herald patch and is specific to pityriasis rosea.
What is topical adapalene?
Topical retinoid
How long a break in between topical steroid courses should you aim for in psoriasis?
4 weeks
1st line mx of scalp psoriasis?
NICE recommend the use of potent topical corticosteroids used once daily for 4 weeks
Describe the rash typically seen in SLE
Livedo reticularis –> a purplish, non-blanching, reticulated rash caused by obstruction of the capillaries resulting in swollen venules.
Mx of eczema herpeticum?
IV antivirals
What is toxic epidermal necrolysis (TEN)?
A potentially life-threatening skin disorder that is most commonly seen secondary to a drug reaction.