core IM Flashcards
SIRS
T >100.4
T <96.8
RR >20
HR >90
WBC >12000
WBC <4000
WBC >10% bands
PCO2 <32 mmHg
Sepsis
2 SIRS +
confirmed OR suspected infection
Severe sepsis
sepsis +
-signs of end organ damage
-hypotension <90
lactate >4
Septic shock
severe sepsis + persistent
-end organ damage
-hypotension <90
-lactate >4
Duke major criteria
1) Bcx + typical (staph, v. strep, enteroccus)
2) evidence of endocaridal involvement on echo
Duke minor criteria
-predisposing factor
-temp >38
-vasc phen (art/sept emboli, pulm infarcs, mycotic aneurysm, conj hemorrhage, janeway lesions, CNS infarct)
-imm phen (glomerulonephritis, osler nodes, roth spot, +RF
-micro evidence atypicals
+ Duke
-2M
-1M + 3m
-5m
atypicals in endocard
E. coli
GA strep
GB strep
HACEK
fungi
HACEK
haemophilus
aggregatibacter
cardiobacterium
eikenella
kingella
CRAB criteria
-hypercalcemia
-renal impairment
-anemia
-bone lesions
CHF GDMT
-RAASi (ARNi, ACEi, ARB)
-BB (carvedilol, metoprolol)
-mineralocorticoid (spiranolactone, eplerenone)
-SGLT2i (dapagliflozin, empagliflozin)
-diruetics (furosemide, torsemide)
Group 1 PH
PAH: damaged or narrowed arteries to lungs
Group 2 PH
left-sided HF
Group 3 PH
lung disease and/or hypoxia
(OSA, fibrosis, COPD)
Group 4 PH
pulmonary artery obstruction/thromboemboli
Group 5 PH
unknown or multiple factors
(p vera, essential thrombocythemia)
cellulitis organism
staph and strep
erysipelas
strep pyogenes
CAP organisms
-strep pneumo
-h fluenza
-kelbsiella
-legionella
-mycoplasma pneum
-chlamydia
-pseudamonas
meningitis organism
strep pneum
n meningitidis
COPD exacerbation tx
-bronchodilator (alb+iprat)
-prednisone 40
-abx (amox-clav, azithromycin, doxy)
-oxygen
COPD imaging
CXR
HRCT
COPD labs
ABG
AAT
CBC
CHF labs
BNP
Troponin
Elec/BUN/creatinine
LFT
CBC
thyroid
glucose
CHF imaging
CXR
Echo
Sepsis labs
CBC
BMP
LFT
lactate
Coag panel
procalcitonin
CRP
ABG
Sepsis infectious w/u
Bcx
site cx (Ucx, CSF, wound)
RPP
fungal panel
Sepsis imaging
CXR
Abd US
CT/MRI
Pneumonia labs
CBC
BMP
Procalcitonin
CRP
ABG
SBP abx
Ceftriaxone
Pip-tazo
meds for hepatic encephalopathy
lactulose
rifaximin
meds for ascites/SBP
diuretics (spiranolactone/furosemide)
albumin
meds variceal bleeding
vasoactive (terlipressin, octreotide, somatostatin)
abx (ceftriaxone)
Hepatorenal syndrome drugs
vasoconstrictors (terlipressin, midodrine, norepi)
albumin
coagulopathy drugs in liver failure
vitamin k
FFP, platelets, or cryoprecipitate
meds for organ support in liver failure
N-acetylcysteine
prednisolone (no infection)
Granulocyte colony-SF
probiotics
preventative drugs in liver disease
PPI - prevent GI bleeding
BB
MM diagnostic criteria
CRAB: Calcium elevation, Renal failure, Anemia, Bone lesions.
Nephrotic syndrome diagnostic criteria
Proteinuria >3.5 g/day, hypoalbuminemia, hyperlipidemia, and edema.
AKI diagnostic criteria
Cr ≥0.3 mg/dL within 48 hours, or ≥1.5 times baseline within 7 days, or urine output <0.5 mL/kg/h for 6 hours.
HHNS diagnostic criteria
Hyperglycemia (>600 mg/dL), high serum osmolality (>320 mOsm/kg), and absence of significant ketosis.
elevated BP
120–129/<80 mmHg.
Stage 1 BP
130–139/80–89 mmHg.
Stage 2 BP
≥140/90 mmHg.
Hypertensive Emergency
BP >180/120 mmHg with end-organ damage.
GOLD 1
Mild (≥80%)
GOLD 2
Moderate (50–79%).
GOLD 3
Severe (30–49%).
GOLD 4
Very severe (<30%).
BP goals in HTN emergency
-25% within minutes to 1 hour
-160/100 to 110 mm Hg within the next 2 to 6 hours
-back to normal over 24 to 48 hours
MIST
Metabolic
Infective
Structural
Toxins
GDMT CHF
RAAS inhibitor
BB
MRAs
SGLT2 inhibitor
Diuretics