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Landmark trials > Cardiology > Flashcards

Cardiology Flashcards

1
Q

BHAT

A

Propranolol after acute myocardial infarction

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2
Q

CLARITY trial

A

Adding clopidogrel to STEMI management

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3
Q

MIRACL trial

A

Atorvastatin reduces recurrent ischemia post-ACS

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4
Q

PLATO trial

A

Ticagrelor superior to clopidogrel for ACS

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5
Q

TNT trial

A

Intensive statin therapy in coronary heart disease

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6
Q

PROVE IT trial

A

High-dose statin regimen reduces mortality

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7
Q

CURE trial

A

Clopidogrel reduces death from CV disease in ACS without ST-elevation

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8
Q

CARE trial

A

Statins in coronary artery disease

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9
Q

SAVE trial

A

Captopril after acute MI reduces mortality and morbidity

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10
Q

RALES trial

A

Spironolactone decreases all-cause mortality in heart failure patients

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11
Q

HOPE trial

A

Ramipril significantly reduces cardiovascular events in high-risk patients with normal ejection fractions

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12
Q

CONSENSUS

A

Enalapril reduces mortality in severe heart failure

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13
Q

EPHESUS trial

A

Eplerenone in heart failure after MI

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14
Q

DOSE trial

A

Loop diuretic strategies in acute decompensated

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15
Q

CHARM-Alternative trial

A

Angiotensin-receptor blockers in HF

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16
Q

ATLAS trial

A

high dose ACE inhibitor dosing in chronic HF

17
Q

PARADIGM-HF trial

A

Valsartan-neprilysin inhibitor vs. enalapril in patients with heart failurePARADIGM-HF trial: Valsartan-neprilysin inhibitor vs. enalapril in patients with heart failure

18
Q

ACTIVE trial

A

Dual antiplatelet therapy in afib

19
Q

RACE-II trial

A

Lenient non-inferior to strict rate-control in afib & less medication needed

20
Q

SPAF trial

A

Warfarin and aspirin reduce the risk of stroke in atrial fibrillation

21
Q

ROCKET AF

A

Rivaroxaban non-inferior to warfarin and lower incident of bleeding in AF

22
Q

HAS-BLED score

A

Bleeding risk in atrial fibrillation

23
Q

AFFIRM trial

A

Rate-control main approach vs. rhythm-control in atrial fibrillation (less adverse events no difference mortality)

24
Q

DASH trial

A

Diet change significantly reduces blood pressure (rich in fruits and vegetables and low in saturated and total fat)

25
Q

SPRINT

A

Intensive (120) better than standard (140) blood pressure control in pts w/ HTN and CV risk

26
Q

Lee index

A

Risk of perioperative cardiac events

27
Q

Wells DVT criteria

A

Clinical prediction model for deep vein thrombosis

28
Q

CARESS trial

A

Dual antiplatelet therapy superior to monotherapy in symptomatic carotid stenosis w/o increase risk of bleeding

Landmark trials (6 decks)

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