Core Flashcards
AF - Mx post DC cardioversion
- High risk of stroke (raised CHADSVASC) - continue lifelong anticoagulation
- Low risk of stroke - continue anticogaulation for 4 weeks the stop
Third degree HB
- P waves not related to QRS
- Ventricular escape rhythm : 35-40 bpm
GRACE score
Helps to decide mx of Unstable angina and STEMI
<3% : Low
Conservative mx
Dual antiplatelet therapy for 12 months
aspirin, plus either:
ticagrelor, if not high bleeding risk
clopidogrel, if high bleeding risk
3-6% : Intermediate
>6% : High
- Clinically unstable - Immediate PCI
- Grace score >3% - Coronary angiogram with PCI withi 72 hours
* 300mg asprin - then give Fondaparinux, prasugrel or ticagrelor, and refer for coronary angiography within 72 hours
Ace inhibitors SE
Used in hypertension and HF
1. Cough
2. Angio-odema
3. Hyperkalaemia
4. U+Es checked before starting - baseline increase of creatinine up to 30% from baseline
4. Avoid in ;
* Pregnancy and breast feeding
* Renovascular disease - bilateral renal artery stenosisa
PEA
- Start Chest compressions before starting IV adrenaline
Amiodone ALS
Amiodarone should be given to patients in ventricular fibrillation (VF) or pulseless ventricular tachycardia (VT).
Hypokalaemia
U waves
small or absent T waves (occasionally inversion)
prolong PR interval
ST depression
long QT
Hypertrophic obstructive cardiomyopathy : Genes
(HOCM) is an autosomal dominant disorder of muscle tissue caused by defects in the genes encoding contractile proteins.
most common cause of sudden cardiac death in the young.most commonly due to ventricular arrhythmias
hypertrophic obstructive cardiomyopathy (HOCM) : Mx
Management
Amiodarone
Beta-blockers or verapamil for symptoms
Cardioverter defibrillator
Dual chamber pacemaker
Endocarditis prophylaxis*
hypertrophic obstructive cardiomyopathy (HOCM) : CI drugs
- Angiotensin-converting enzyme (ACE) : educe afterload which may worsen the LVOT gradient.
- nitrates
- inotropes
BP classification
Hypertension - When to treat
First-degree heart block is a normal variant in an athlete. It does not require intervention
Anal ulceration may be caused by nicorandil
Statin - interactions
Clarithromycin inhibits CYP3A4, an enzyme involved in the metabolism of many drugs including simvastatin. When CYP3A4 is inhibited by clarithromycin, it can lead to increased levels of simvastatin in the body,