COPD Flashcards
Definition of COPD
- common preventable disease characterised by persistent airflow limitation usually progressive and associated to enhanced chronic inflammatory response.
- exacerbation and co-morbidities are common and contribute to overall severity
- chronic airflow limitiation caused by a mix of small airway disease (bronchitis) and parenchymal destruction (emphysema)
prevalence of copd in the uk
- how many it kills
- smoking related
- how many have it
30,000 people in the UK killed with COPD every yr
2nd biggest killer after cancer
20% not smoking related
3 million have it with 2 million undiagnosed
BLF,2018
How does COPD relate to onset of smoking cessation
NICE 2010
- dont smoke or not suscptible to smoke then at 75 your lung capacity will be at 75%
- stop at 45 will be at 45% at 75
- stop at 65 then lung capacity will be 15% at 75
3 concepts related to COPD
- exercise limitiation
- dyspnoea spiral
- hypoxic drive
explain how COPD limits exercise
through V/Q mismatch and increased work of breathing
COPD leads to V/Q mismatch due to increase physiological lung dead space over tidal volume VD/VT meaning decrease o2stats, higher co2 so decrease pH. this activates chemoreceptors so increase ventilatory requirenment causing breathlessness/ dyspnoea.
copd increases work of breathing due to airflow obstruction (bronchitis) and decrease elastic recoil (parenchymal destruction) which decreases ventilatory capacity causing dyspnoea
explain dyspnoea spiral and how it relates lactic acid to breathlessness
acts in a cycle so:
disease causes disability ie breathlessness that causes inactivity which causes deconditioning and atrophy of muscles, leading to more breathlessness, causing more disability so cycles round to reducing inactivity further
also atrophy of muscles leads to anaerobic metabolism at low work rates increasing lactic acid and stimulation of ventilation causing more breathlessness
causes dynamic hyperinflation during exercise so cant respire properly
hypoxic drive to breathe
lose the drive to breathe due to CO2 (hypercapnia)- body starts to use oxygen receptors instead of co2 receptors to regulate breathing. –as high levels of arterial co2 over time mean the chemoreceptors become less sensitive to change so rely on the o2 receptors causing increase respiratory rate. Therefore, cant put on high oxygen as will lose the drive to breathe.
results of exercise limitation of copd
Lee and holland 2014 lower cardio respiratory fitness (vo2 0.5-1.6l/min norm 3.5) altered respiraotry mechanism gas exchange abnormalities respiratory and peripheral muscle abnormality dyspnoea fatigue and impaired exercise capacity reduced pa nutritional deficit comorbid balance impair sleep deficit depression, anxiety and reduced SE
symptoms of copd
nhs uk 2018
wheeze, dyspnoea, cough, chest infections, weight loss, fatigue and oedema
levels of depression in copd
mills 2001 45%
what are the 5 goals of pulmonary rehab
- alleviate symptoms
- decrease disbailitiy
- restore functional capabilities
- increase quality of life
- maintain long term benefits
what are the 6 components of pulmonary rehab
1.physical training
2.disease education
3.nutritional intervention
4.psychological intervention
5. social intervention
6. behavioural intervention
NICE NATIONAL INSTITUTE FOR HEALTH AND CARE EXCELLENCE 2010
HILL AND BURTIN statement
also includes smoking cessation and states more than just prescribing exercise but also the psychosocial and lifestyle changes that copd brings that needs targeting
2013
what is the most disabiling symptom of copd and how can it be helped
dyspnoea= vestbo et al 2013
foward-lean position sitting, pursed lip breathing and use of a rollator (hill and burtin 2013)
definition of pulmonary rehab
an individually tailored, multi-disciplinary programme of care to optimise patients physical and social performance and autonomy
NICE 2010
conditions of PR 8
NICE 2010 states
1)make PR available to all includiing those with recent hospitlisation for acute exacerbation
2. tailor multi-component multidisciplinary intervention that targets the 6 components of rehab
3.hold at times to suit patient to improve concordance and effectiveness
4. offer to all patients who consider themselves functionally disabled by COPD (But is not suitable for those unable to walk, unstable angina or recent mi)
5.patients should be made aware of the benefits of PR and the commitement required to gain these
6. should be at least 6 weeks duration, min 2xweekly supervised sessions
7. supervised, individually tailored, progressive both aerobic and restistance training
8 defined and structured
what are the 3 sources of guidelines for PR
American college of sports med 2013
american thoracic society/ european respiratory society 2013
american association of cardiovascular and pulmonary rehab 2011
what are the British Thoracic society 2001 recommendations for exercise training in pr
aerobic: duration 4-12 weeks supervised 2-5x per week duratation 20-30 minutes intensity: 60% peak velocity or peak vo2= better than using HR large muscle groups ensure progressive overload programme
strength:
beneficial in addition to aerobic
improves endurance rather than max capacity
can begin unloaded if severe
other factors
- can be done at home but out patient clinic more effective as supervised technique and social,
- supplemental o2 recommended if stats under 90%^
- education ineffective by itself but important
- coping and SE strategies
- nutrition ineffective alone but useful with exercise
managament of COPD recomendation
vestbo et al 2013 GOLD global obstructive lung disease guidelines
GOLD assessment of copd recommendations
- recommends spirometry
- determine the impact of disease on patient health status
- severity of airflow limitation
- risk of future exacerbations
GOLD reducing risk factors
- smoking cessation
- consider other pollutants
- use available vaccines
managing stable copd gold
- relieve symptoms with bronchodilator
- prevent progression
- improve exercise tolerance
- improve health status
- prevent exacerbations
- reduce mortality
- level FEV1 may be inadequate descriptor
manage exacerbation COPD
pharma
level of depression in copd
45% Mills 2001