COPD Flashcards
Risk factors for developing COPD
Cigarette smoke, occupational chemicals, air pollution severe recurrent respiratory infections, and alpha-1 antitrypsin deficiency
Define COPD
Preventable and treatable disease state characterized by airflow limitation that is not fully reversible. Usually progressive and associated with an abnormal inflammatory response of the lungs to noxious particles and gases, primarily caused by cigarette smoking
Types of COPD
Chronic Bronchitis and emphysema
Chronic bronchitis
Presence of chronic productive cough for three months and each of two consecutive years in a patient that other causes of chronic cough have been eliminated
Define emphysema
Abnormal permanent enlargement of air spaces distal to the terminal bronchioles, accompanied by destruction of the walls and without obvious fibrosis
Common manifestations of COPD
Chronic inflammation found in airways, lung parenchyma of respiratory bronchioles and alveoli, and pulmonary blood vessels
PathoGenesis of COPD
Complex and involves many mechanisms, with an inflammatory process different from that of asthma. Systemic manifestations
Defining feature of COPD
Not fully reversible airflow limitation during forced exhalation that is caused by loss of elastic recoil and airflow obstruction secondary to mucus hypersecretion, mucosal edema, and bronchospasm. Gas exchange abnormalities result in hypoxemia and hypercapnia
Diagnosis of COPD should be considered when?
Patient over the age of 40 with symptoms of cough, sputum production, or dyspnea, and/or a history of exposure to risk factors for the disease
Symptoms of COPD
Chronic intermittent cough is the earliest symptoms; sputum mayor may not be present, symptoms are progressive
Classifications of COPD
Mild, moderate, severe, and very severe; depends on severity of obstruction
Complications of COPD
Cor pulmonale, exacerbations, respiratory failure; anxiety and depression often occur in the picture
Cor pulmonale with COPD
Hypertrophy of the right side of the heart, with or without heart failure, resulting from pulmonary hypertension and is a late manifestation of chronic pulmonary heart disease
Exacerbations of COPD
Signal by a change in the patient’s usual dyspnea, cough, and/or sputum that is different from the usual daily patterns. These patients require changes in management and can have significant Mortality if it’s not appropriately treated
Confirmation of COPD
Done through pulmonary function test. Is made when FEV1/FVC ratio is less than 70% and related symptoms are present