Controlled medication- Phosphodiaesterase-4 inhibitors Flashcards

1
Q

Roflumilast
(daliresp)
Dosage form

A

Tablets

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2
Q

Roflumilast
(daliresp)
Dosing

A

Adult
-250 mcg daily for 4 weeks followed by 500 mcg by mouth daily
COPD only

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3
Q

Adverse Effect

A
  • AE: HA, weight loss, diarrhea, nausea * Monitoring: liver function test, weight * DI: CYP3A4 (major), CYP1A2 (minor) * CI: Child-Pugh class B or C
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