Controlled medication- Phosphodiaesterase-4 inhibitors Flashcards
1
Q
Roflumilast
(daliresp)
Dosage form
A
Tablets
2
Q
Roflumilast
(daliresp)
Dosing
A
Adult
-250 mcg daily for 4 weeks followed by 500 mcg by mouth daily
COPD only
3
Q
Adverse Effect
A
- AE: HA, weight loss, diarrhea, nausea * Monitoring: liver function test, weight * DI: CYP3A4 (major), CYP1A2 (minor) * CI: Child-Pugh class B or C