control of reproduction in male Flashcards

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1
Q

when does puberty start?

A

several definitions:
age of first reproductive behaviour

age of first ejaculation

age at first spermatozoa in ejaculate

age at first spermatozoa in urine

age when threshold number of spermatozoa in ejaculate

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2
Q

what does puberty cause?

A

the resulting in the ability to accomplish fertilisation

sperm production will be continuous from then on

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3
Q

what is reproductive activity divided into?

A

physiological changes, hormonal

behavioural changes

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4
Q

what is responsible for the endocrine changes in the male?

A

hypothalamic-pituitary-gonadal axis

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5
Q

what hormone does the hypothalamus produce?

A

GnRH - gonadotropin-releasing hormone

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6
Q

what hormone does the pituitary gland produce?

A

FSH and LH

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7
Q

what hormone does the testicles produce?

A

testosterone

inhibin

activin

oxytocin

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8
Q

how does the season affect the endocrine changes in seasonal breeders, in females?

A

the pineal gland detects changes in daylight

produces melatonin during the dark hours

melatonin concentrations either inhibit or excite the HPG axis

there is still activity e.g. sperm production

if given enough encouragement, will mate out of breeding season

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9
Q

how can the season affect the efficiency of reproduction in male seasonal breeders?

A

depending on the season, it can alter the size of the testis which will change the amount of testosterone

in rams, August, September and October is the largest testis

September, October, and November produce the most amount of testosterone

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10
Q

how does GnRH do in the male?

A

the mechanism is the same as in the female

releases differently, in frequent, intermittent bursts

there is not a large surge

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11
Q

how does GnRH travel?

A

secreted by hypothalamus

goes via hypothalamo-hypophyseal portal system

acts on anterior pituitary

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12
Q

what does FSH do in the male?

A

initiates spermatogenesis

causes spermatogonia to become secondary spermatocytes

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13
Q

where does FSH travel?

A

secreted from the anterior pituitary gland

travels via the bloodstream

acts on the Sertoli cells in the testis

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14
Q

how is the FSH controlled?

A

GnRH = increase of FSH

inhibin increase = FSH decrease

activin increase = FSH increase

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15
Q

what does LH do the male?

A

it controls the testosterone secretion

cholesterol is a precursor

therefore, testosterone secretion is also pulsatile

pulsatile LH = Leydig cells unresponsive to continuous high LH

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16
Q

how does the LH travel?

A

from pituitary glands

through the bloodstream

acts on the Leydig cells

17
Q

how are the LH pulse secretions?

A

occur far more frequently than in woman

18
Q

what does testosterone do in the male?

A

drives sperm production

develops male genitalia

causes pubertal changes and accelerates growth and muscle development

accessory glands growth and function

controls libido and reproductive behaviour

19
Q

how does testosterone travel?

A

secreted in Leydig cells

acts on the body parts

causes negative feedback loop to decrease LH

20
Q

how is activin controlled?

A

decrease in the production of sperm causes the increase of activin

21
Q

how is inhibin controlled?

A

increase in sperm production causes the increase of inhibin

22
Q

where are activin and inhibin produced?

A

in the Sertoli cells

23
Q

what does activin or inhibin cause?

A

increase in inhibin = negative feedback loop, decrease in FSH

increase in activin = positive feedback loop, increase in FSH

24
Q

what does oxytocin effect?

A

acts on myometrium of the seminiferous tubules, rete testes and epipdidymis, causing contractions

25
Q

where is oxytocin produced?

A

either leydig or sertoli cells

26
Q

what causes behavioural changes?

A

testosterone drives male reproductive behaviour

27
Q

what are the changes in behaviour?

A

increase libido

increase vocalisation

flehmen - entry of pheromones into vomeronasal organ