Control of gene expression - 1.3 Flashcards
Transcription
- RNA polymerase moves along DNA unwinding the strand
-hydrogen bonds break
-RNA synthesises a primary transcript of mRNA while adding RNA nucleotides to the strand - hydrogen bonds get added to the other strand
-primary transcript of mRNA gets changed into the mature transcript of mRNA
-mature mRNA can now leave the nucleus and travel to the ribosome
what is gene expression?
the activation of certain genes to produce particular protiens
RNA
-type of sugar
-bases
-number of strands
-ribose sugar
-adenine, uracil, guanine, cytosine
-one
function of mRNA
carries a copy of DNA code from nucleus to the ribosome
function of tRNA
found in cytoplasm where it binds to specific amino acids and transports to ribosome
function of rRNA
forms a complex with protein molecules to make the ribosome
what does a codon do?
code for a specific amino acid
RNA splicing
- introns of the primary transcript are removed
-exons are joined together to form the mature mRNA
what types of RNA is required for translation
tRNA and rRNA
what are ribosomes composed of
-rRNA and proteins
what does tRNA consist of
-anticodon
-attachment site for amino acid
process of translation
-begins at mRNA
-tRNA brings over specific amino acids
-tRNAs anticodons bind to codons by complimentary base pairing, translating the genetic code into a sequence of amino acids
-peptide bonds join amino acids together
-tRNA leaves ribosome as polypetide is formed
what happens in RNA splicing
different protiens can be expressed due to alternative RNA splicing
-just depends on which exons are retained