Control of blood glucose concentrations Flashcards
Where are insulin and glucagon secreted from
Cells in pancreas called islets of Langerhans. A- Glucagon , B- Insulin.
How does insulin lower blood glucose concentration
B secrete insulin which binds to specific receptor on cell membrane of liver cell, increasing permeability so muscle take more glucose- increase channel proteins. Insulin activate enzyme converting glucose to glycogen(glycogenesis)
How does Glucagon raise blood glucose concentration
A-secrete it, bind to specific receptor of liver cell, activate enzyme breaking glycogen to glucose - glycogenolysis. Also activate enzyme converting amino acid to glucose - gluconeogensis
Role of adrenaline in regulating blood glucose
increases concentration as secreted by adrenal gland bind to receptor on surface of liver cell activating glycogenolysis also inhibits glycogensis
What is the secondary messenger model
Adrenaline bind to protein receptor on surface of liver cell, activate enzyme adenylate cyclase which converts ATP to chemical signal called cAMP which acts as a secondary messenger it activates enzyme protein kinese a breaks glycogen to glucose