Contrast Studies Flashcards
what are the 3 most common types of contrast studies?
GI, urogenital, spinal cord
why do we use contrast agents?
they cause a difference in the density and organ visibility
types of contrast agents
positive (appears white or radiopaque) and negative (appears black or radiolucent)
what are the two positive contrast medias?
- Barium sulfate and BIPs (barium impregnated polyethylene spheres)
- water-soluble organic iodides (can be ionic or non-ionic)
Barium sulfate
used for GI studies, administered orally or rectally, high atomic # (high atomic # = higher density), insoluble
what are the 2 systems to measure Barium sulfate?
- weight to volume (w/v)
- weight to weight (w/w)
what forms is Barium sulfate available in?
powder, liquid suspension, paste
disadvantages of Barium sulfate
can’t use if perforation is suspected, aspiration in lung can be fatal, and blocks ultrasound waves
advantages of Barium sulfate
low cost, delineates mucosal walls well, palatable, not absorbed through intestine, doesn’t become diluted with secretions
BIPS
used to determine motility issues
comes in capsule form
better evaluation of gastric emptying times
water-soluble organic iodides
mix readily with blood/body fluids and are excreted through the kidneys
what are the 2 types of water-soluble organic iodides?
ionic (molecules dissociate and cause changes in osmolality) and non-ionic (molecules remain whole)
ionic water-soluble organic iodides
triiodinated compounds derived from benzoic acid ring structure
made up of an anion (-) and a cation (+)
cation: salt (sodium or megulumine)
anion: includes benzene ring with 3 iodine atoms + carboxyl group + other side chains (Diatrizoate or iothalamate)
when are ionic water-soluble organic iodides used?
when GI perforations are suspected
comes in oral form: Meglumine diatrizoate and sodium diatrizoate (Gastrografin)
disadvantages: bitter taste, expensive, hypertonicity effects
injectable form of ionic water-soluble organic iodides
used for excretory urography, intraarticular studies, draining wound studies, and fistulography
ex: sodium diatrizoate (Hypaque), meglumine diatrizoate (Hypaque M), iothalamate meglumine (Conray)
advantages: less viscous
disadvantages: hypertonicity effects, irritating to brain and spinal cord, anaphylaxis
nonionic water-soluble organic iodides
doesn’t dissociate
doesn’t increase osmolality of plasma
ideal for studies involving spinal cord (myelography) and respiratory tract
injectable form of nonionic water-soluble organic iodides
Iohexol (Omnipaque), iopamidol (Isovue), ioversol (Opitray), iopromide (Ultravist), Iotrolan (Isovist, Osmovist), ioxilan (Oxilan), nonionic dimer iodixanol (Visipaque)
advantages: fewer side effects, rapid transit time, reabsorbed after extraluminal leakage, doesn’t become dilute
disadvantages: expensive
how else can ionic and nonionic injectable contrast media be classified?
monomer and dimer
monomer: 1 benzene ring
dimer: 2 benzene ring
osmolality decreases when there are more iodine molecules
ionic monomer has highest osmolality and nonionic dimer has the lowest
negative contrast media
radiolucent gases: air, nitrous oxide, oxygen, CO2)
less mucosal detail compared to positive
cons: overinflation, use of room air can produce air embolism that can cause cardiac arrest
what is it called when negative contrast medias are used with positive contrast medias?
a double contrast study
esophagography
used to assess status of esophagus, potential motility issues, and surrounding tissues
ideal to use fluoroscopy
lateral and DV positioning used
indications of an esophagography
abnormal swallowing, foreign body obstruction, dysphagia (difficulty swallowing), megaesophagus, regurgitation of undigested food, head/neck trauma
media and doses for an esophagography
barium sulfate liquid or paste, oral aqueous iodine if perforation suspected
standard dose: 5-20 mL
use organic iodine agent instead if aspiration and asphyxiation of contrast agent is of concern
double contrast study esophagography
obtain images during swallowing and during pause that follows swallowing of contrast
usually anesthetized
if reflux patient, administer only air
upper GI
evaluates the morphology of the stomach and small intestines, visualizes extramural/ mural/ intramural lesions of GI tract, gastric emptying and pyloric function
what could be affected in the GI tract if sedation is used?
the GI tract motility could be altered
indications of an upper GI study
recurrent vomiting, hematemesis, anorexia, melena, chronic weight loss, suspected foreign body, or if survey radiographs are non-conclusive
media and dose for upper GI study
barium sulfate suspension 60%
8-10 mL/kg for dogs and cats <10kg
5-7 mL/kg for dogs 10-40kg
3-5 mL/kg for dogs >40kg
iodinated contrast agents: 2-4 mL/kg of body weight added to water to equal 13 mL/kg
double/ negative contrast: 20 mL/kg via orogastric tube