Contrast Flashcards
types of compounds
metal salts
organic iodides
gaseous air
[types] metal salts
bismuth, lead, barium
[MC, poi] metal salts
barium sulfate, GI tract
[types] organic iodides
water soluble iodides
CM:
Ionic: HOCM
Non-Ionic: LOCM
Ethiodized/Oily CM
[indication] ethiodized CM/oil
lymphography - stay longer
MRI contrast charac
-enhance and improve tissue property
-tissue specificity: attach to poi
-reasonable cleaning period: excrete
-low toxicity
-long shelf life
classification-magnetic property
paramagnetic
superparamagnetic
diamagnetic
[charac] paramagnetic
-slightly magnetic
-directly attaches to H atoms
-consists of metal ion bonded w/ organic moiety (DTPA)
[metal ions-other name] paramagnetic ions
lanthanides
gadolinium, iron, manganese, dysprosium
[PM] low dose = [..]
shortens T1
[PM] high dose = [..]
T2 relaxation
[term] how CM is stored
bioaccumulation methods/ways
[gadolinium-based] category of bioaccumulation methods
-extracellular fluid agents (ECF)
-blood pool contrast agents
-organ-specific contrast agents
[ex] organ specific contrast agents
iron oxide and liposomes
[organ specific contrast agents]imported into cells thru phagocytosis
iron oxide
distributed in extracellular space mimics iodinated CM of CT
renal excretion
extracellular fluid agents (ECF)
remains in the intravascular space
excreted more slowly
blood pool contrast agents
manganese chelates: [..]
manganese dipyridol diphosphonate (Mn-DPDP)
manganese enhance [..]
t1 signal intensity
[indication] manganese
hepatic lesion
highly magnetic than paramagnetic
takes adv of blood
small solid particles w/c acts like ferromagnetic subs; suspended colloids
superparamagnetic
[ex] superparamagnetic, reduces T2 signals
iron oxide particle
[ex] superparamagnetic; still under investigation; prostate CA
iron platinum contrast agents
no magnetic attraction
diamagnetic
diamagnetic is used in [..]
chemical exchange saturation transfer (CEST)
magnetization is transferred from other molecule to water molecule saturation
chemical exchange saturation
[ex] diamagnetic
BaSO4
Clay-bentonite
Kaolin
Iron Ferric Ammonium Citrate
[classi accdg to chemical design] positive CA
paramagnetic (except dyposium)
brighter but vary
bright on T1-W
[classi accdg to chemical design] nagative CA
darker
oxides: superparamagnetic
reduces T2 signals
CM introduction routes
IV
Oral: GI tract scans