Contrast Flashcards

1
Q

types of compounds

A

metal salts
organic iodides
gaseous air

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2
Q

[types] metal salts

A

bismuth, lead, barium

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3
Q

[MC, poi] metal salts

A

barium sulfate, GI tract

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4
Q

[types] organic iodides

A

water soluble iodides
CM:
Ionic: HOCM
Non-Ionic: LOCM
Ethiodized/Oily CM

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5
Q

[indication] ethiodized CM/oil

A

lymphography - stay longer

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6
Q

MRI contrast charac

A

-enhance and improve tissue property
-tissue specificity: attach to poi
-reasonable cleaning period: excrete
-low toxicity
-long shelf life

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7
Q

classification-magnetic property

A

paramagnetic
superparamagnetic
diamagnetic

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8
Q

[charac] paramagnetic

A

-slightly magnetic
-directly attaches to H atoms
-consists of metal ion bonded w/ organic moiety (DTPA)

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9
Q

[metal ions-other name] paramagnetic ions

A

lanthanides
gadolinium, iron, manganese, dysprosium

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10
Q

[PM] low dose = [..]

A

shortens T1

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11
Q

[PM] high dose = [..]

A

T2 relaxation

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12
Q

[term] how CM is stored

A

bioaccumulation methods/ways

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13
Q

[gadolinium-based] category of bioaccumulation methods

A

-extracellular fluid agents (ECF)
-blood pool contrast agents
-organ-specific contrast agents

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14
Q

[ex] organ specific contrast agents

A

iron oxide and liposomes

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15
Q

[organ specific contrast agents]imported into cells thru phagocytosis

A

iron oxide

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16
Q

distributed in extracellular space mimics iodinated CM of CT
renal excretion

A

extracellular fluid agents (ECF)

17
Q

remains in the intravascular space
excreted more slowly

A

blood pool contrast agents

18
Q

manganese chelates: [..]

A

manganese dipyridol diphosphonate (Mn-DPDP)

19
Q

manganese enhance [..]

A

t1 signal intensity

20
Q

[indication] manganese

A

hepatic lesion

21
Q

highly magnetic than paramagnetic
takes adv of blood
small solid particles w/c acts like ferromagnetic subs; suspended colloids

A

superparamagnetic

22
Q

[ex] superparamagnetic, reduces T2 signals

A

iron oxide particle

23
Q

[ex] superparamagnetic; still under investigation; prostate CA

A

iron platinum contrast agents

24
Q

no magnetic attraction

A

diamagnetic

25
Q

diamagnetic is used in [..]

A

chemical exchange saturation transfer (CEST)

26
Q

magnetization is transferred from other molecule to water molecule saturation

A

chemical exchange saturation

27
Q

[ex] diamagnetic

A

BaSO4
Clay-bentonite
Kaolin
Iron Ferric Ammonium Citrate

28
Q

[classi accdg to chemical design] positive CA

A

paramagnetic (except dyposium)
brighter but vary
bright on T1-W

29
Q

[classi accdg to chemical design] nagative CA

A

darker
oxides: superparamagnetic
reduces T2 signals

30
Q

CM introduction routes

A

IV
Oral: GI tract scans