Contraindications Flashcards
Ceftriaxone
contraindications
allergy to cephalosporin (seh·fuh·low·spaw·ruhn) antibiotics
Midazolam
Contraindication
known hypersensitivity to benzodiazepines
Salbutamol
contraindications
none
Prochlorperazine
contraindications
- CNS depression (i.e. unconscious or severely intoxicated)
- patients < 21 years of age (children and young adults are more susceptible to extrapyramidal (involuntary movements that you cannot control)reactions with Prochlorperazine
Paracetamol
contraindications
children < 1 month of age
Ondansetron
contraindications
apomorphine (injection used in the treatment of severe Parkinson’s disease - leads to profound hypotension and loss of consciousness)
normal saline
contraindications
none
Naloxone
special notes
- following an opioid-associated cardiac arrest should not be administered
- following head injury should not be administered
Naloxone
contraindications
none
Morphine
contraindications
- history of hypersensitivity
- renal impairment/failure
- the late second stage of labour
Methoxyflurane
contraindications
- pre-existing renal disease
- known (or genetic susceptibility) to malignant hyperthermia
Ketamine
contraindications
suspected non-traumatic brain injury with severe hypertension (SBP > 180)
Ipratropium Bromide
contraindications
known hypersensitivity to atropine or its derivatives
Glyceryl Trinitrate
Significant interactions
Phosphodiesterase 5, which increases the effects of PDE5 inhibitors resulting in profound hypotension
DO NOT ADMINISTER IF
- 12 hours since the last dose of avanafil (Spedra)
- 24 hours for sildenafil (viagra) or vardenafil (Cialis)
- 48 hours for tadalafil (Levitra)
Riociguat (Adempas) which are used for pulmonary arterial hypertension. it increases the effects of riociguat so DO NOT ADMINISTER IF TAKING THE DRUG.
Glyceryl Trinitrate
contraindications
- BP < 100 mmHg
- HR > 150 bpm
- HR < 50 bpm (except in autonomic dysreflexia)
- Ventricular tachycardia
- PDE5 inhibitors (current/recent use)
- Riociguat (current use)
- Bleeding in pregnancy
Glucagon
contraindications
none
Dextrose 10%
contraindications
none
Dexamethasone
Contraindications
Known hypersensitivity
Fentanyl
Contraindications
- History of hypersensitivity
- Late second stage of labour
- Serotonin syndrome
- Monoamine oxidase inhibitors
(MAOIs) within the previous 14 days
Aspirin
Contraindications
- Hypersensitivity to aspirin/salicylates
- Actively bleeding peptic ulcers
- Bleeding disorders
- Suspected dissecting aortic aneurysm
- Chest pain associated with psychostimulant OD if SBP >160 mmHg
Adrenaline
Contraindications
Hypovolaemic shock without adequate fluid replacement
Olanzapine
Contraindications
none
Ligocaine
Contraindications
Known hypersensitivity to lidocaine or related local anesthetics
Heparin
Contraindications
- Known allergy or hypersensitivity
- Active bleeding excluding menses
- oral anticoagulants
- bleeding disorders
- history of heparin-induced thrombocytopaenia (HIT)
- severe hepatic impairment/disease, including oesophageal varices
- recent trauma or surgery (<3 weeks)
