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Drugs > Contraindications > Flashcards

Contraindications Flashcards

1
Q

Ceftriaxone
contraindications

A

allergy to cephalosporin (seh·fuh·low·spaw·ruhn) antibiotics

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2
Q

Midazolam
Contraindication

A

known hypersensitivity to benzodiazepines

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3
Q

Salbutamol
contraindications

A

none

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4
Q

Prochlorperazine
contraindications

A
  • CNS depression (i.e. unconscious or severely intoxicated)
  • patients < 21 years of age (children and young adults are more susceptible to extrapyramidal (involuntary movements that you cannot control)reactions with Prochlorperazine
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5
Q

Paracetamol
contraindications

A

children < 1 month of age

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6
Q

Ondansetron
contraindications

A

apomorphine (injection used in the treatment of severe Parkinson’s disease - leads to profound hypotension and loss of consciousness)

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7
Q

normal saline
contraindications

A

none

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8
Q

Naloxone
special notes

A
  • following an opioid-associated cardiac arrest should not be administered
  • following head injury should not be administered
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9
Q

Naloxone
contraindications

A

none

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10
Q

Morphine
contraindications

A
  • history of hypersensitivity
  • renal impairment/failure
  • the late second stage of labour
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11
Q

Methoxyflurane
contraindications

A
  • pre-existing renal disease
  • known (or genetic susceptibility) to malignant hyperthermia
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12
Q

Ketamine
contraindications

A

suspected non-traumatic brain injury with severe hypertension (SBP > 180)

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13
Q

Ipratropium Bromide
contraindications

A

known hypersensitivity to atropine or its derivatives

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14
Q

Glyceryl Trinitrate
Significant interactions

A

Phosphodiesterase 5, which increases the effects of PDE5 inhibitors resulting in profound hypotension

DO NOT ADMINISTER IF
- 12 hours since the last dose of avanafil (Spedra)
- 24 hours for sildenafil (viagra) or vardenafil (Cialis)
- 48 hours for tadalafil (Levitra)

Riociguat (Adempas) which are used for pulmonary arterial hypertension. it increases the effects of riociguat so DO NOT ADMINISTER IF TAKING THE DRUG.

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15
Q

Glyceryl Trinitrate
contraindications

A
  • BP < 100 mmHg
  • HR > 150 bpm
  • HR < 50 bpm (except in autonomic dysreflexia)
  • Ventricular tachycardia
  • PDE5 inhibitors (current/recent use)
  • Riociguat (current use)
  • Bleeding in pregnancy
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16
Q

Glucagon
contraindications

A

none

17
Q

Dextrose 10%
contraindications

A

none

18
Q

Dexamethasone
Contraindications

A

Known hypersensitivity

19
Q

Fentanyl
Contraindications

A
  • History of hypersensitivity
  • Late second stage of labour
  • Serotonin syndrome
  • Monoamine oxidase inhibitors
    (MAOIs) within the previous 14 days
20
Q

Aspirin
Contraindications

A
  • Hypersensitivity to aspirin/salicylates
  • Actively bleeding peptic ulcers
  • Bleeding disorders
  • Suspected dissecting aortic aneurysm
  • Chest pain associated with psychostimulant OD if SBP >160 mmHg
21
Q

Adrenaline
Contraindications

A

Hypovolaemic shock without adequate fluid replacement

22
Q

Olanzapine
Contraindications

A

none

23
Q

Ligocaine
Contraindications

A

Known hypersensitivity to lidocaine or related local anesthetics

24
Q

Heparin
Contraindications

A
  • Known allergy or hypersensitivity
  • Active bleeding excluding menses
  • oral anticoagulants
  • bleeding disorders
  • history of heparin-induced thrombocytopaenia (HIT)
  • severe hepatic impairment/disease, including oesophageal varices
  • recent trauma or surgery (<3 weeks)
25
Q

Oxytocin
contraindications

A

none, provided all babies have been delivered prior to administration

26
Q

Tenecteplase
contraindications

A
  • Major surgery in the past 3 months
  • Significant head injury in the past 3 months
  • major trauma in the past 3 months
  • Stoke/TIA in the past 3 months
  • ICH (intracerebral brain hemorrhage) at any time
  • GI or genitourinary bleed in the past month
  • Current bleeding disorder, active bleeding (excluding menses) or bleeding tendencies
  • Anticoagulants or glycoprotein IIb/IIIa inhibitors
  • Allergy to Tenecteplase or gentamicin
27
Q

Droperidol
Contraindications

A

None

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