Contraction Flashcards
1
Q
What does ca2+ bind to in order to create a contraction?
A
Troponin C (TnC subunit)
**conformational change shifts tropomyosin to reveal myosin binding site on actin filaments
2
Q
After an action potential the ca2+ must be removed from the cytosol. How is this done?
A
Most pumped back into SR (SERCA) -raised ca2+ stimulates the pumps
Some exits across the cell membrane - sarcolemmal ca2+atpase and na+/ca2+ exchanger
