Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Unit 5 > Contraceptives > Flashcards

Contraceptives Flashcards

1
Q

Primary MOA of hormonal contraceptives

A

inhibition of ovulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

hormonal components of contraceptive

A

estrogen (synthetic)
– ethinyl estradiol (EE)
progestins (synthetic progesterone analogs) –
levonorgestrel (LNG)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

common oral OCPs

A 
monophonic products
biphasic products
triphasic products
quadriphonic products
Progestin only (mini pill)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

non contraceptive benefits of HC’s

A

increased hemoglobin (some OC’s contain Fe2+)
reduced risk of fetal neural tube defects (some contain folate)
decreased vasomotor symptoms (‘hot flashes”) in postmenopausal women
increased BMD in perimenopausal women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

adverse effects of OCPs

A

venous thromboembolism (VTE)
CA
CV effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

greatest risk factors for VTE with OCPs

A

obesity, smokers, HTN, diabetics, recent post-op & previous DVT.

Use progestin only Has in these patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

least risk for VTE is with progestin:

A

levonorgestrel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

CA with OCPs is mostly associated w/ ____

A

unopposed estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

lower EE increases risk of ___

A

failure (pregnancy)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

HC users with HTN have a higher risk of ___ or ___

A

MI; stroke

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

E2 HCs are not recommended for ____, ___ or ___

A

smokers >35, women w/ HTN, migraines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

less serious S/E of HC can be minimized/avoided by adjusting ___

A

E2 and or progestin content

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

transdermal patch that is no longer available

A

Evra (ortho)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

transdermal patch. delivers __/__

A

EE/norelgestromin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

administration of transdermal patch

A

apply 1 patch weekly x 3 weeks, then 1 week with no patch.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

transdermal patch is less effective in women ___

A

> 90kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

vaginal ring: __/__

A

EE/etonogestrel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

administration of vaginal ring

A

left in place x 3 wks

then 1 wk ring free interval

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

vaginal ring return to fertility after removal

A

rapid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

with vaginal ring, users report less ___, ___,___ and ___

A

nausea
acne
irritability
depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Injectable hormonal contraception dosage

A 
Depo provera (DMPA) -- IM q3mo
depo-subQ provera: SC q3mo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

injectable hormonal contraception have improved. ___

A

adherence over OC’s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

side effects of injectables

A

decreased BMD

24
Q

labeling recommends to discontinue injectables after ___

A

2 yrs o f u se

25
Q

__ may be delayed after use of injectable hormonal contraception

A

fertility

26
Q

DMPA:

A

dopo medroxyprogeserone acetate

27
Q

long acting reversible contraception

A

subdermal implant

intrauterine device

28
Q

IUD:

A 
non hormonal (copper)
hormonal
29
Q

subdermal implant duration of use

A

3 year duration of use

30
Q

subdermal implant contains ___ for x ray visualization

A

barium

31
Q

Subdermal implant is not affected by ___

A

BMI

32
Q

subdermal implant is safe immediately ___ or ___

A

postpartum or abortion

33
Q

copper IUD duration of use

A

10 years

34
Q

most effective form of emergency contraception

A

copper IUD

35
Q

main s/e of copper IUD

A

increased menstrual bleeding

36
Q

hormonal IUDs duration of use

A

3-5 years

37
Q

unlike Cu-IUD, hormonal IUDs tend to decrease ___

A

menstrual bleeding

38
Q

IUD can be unsuccessful in up to ___%

A

18%

39
Q

risk o expulsion of IUD immediacy post placental delivery

A

3-27%

40
Q

risk of expulsion of IUD 10min-48h post placenta delivery

A

11-27%

41
Q

risk of expulsion of IUD 4-8 wks post partum

A

0-6%

42
Q

IUD has risk of ___

A

uterine perforation

43
Q

emergency contraception pills:

A 
progestin ECPs (available OTC, no age restriction)
Antiprogestin ECPs (rx only)
44
Q

progestin ECP uses

A

levonorgestrel

45
Q

atiprogestin ECP uses

A

ulipristal acetate

46
Q

antiprogestin is more effective than ___

A

progestin ECP

47
Q

antiprogestin may be taken up. to ____ post intercourse

A

5 days

48
Q

___ is prudent in EPC use

A

prompt use

49
Q

copper IUD is the more effective than ___

A

ECPs.

50
Q

copper IUD may be inserted up to ___ post intercourse

A

10 days

51
Q

abortifacients

A

mifepristone RU-486

52
Q

mifepristone is given with other ___

A

prostaglandins (PO misoprostol)

53
Q

success rates with aborticfacents

A

> 90% with pregnancies <49 days

54
Q

EE is metabolized mainly by __

A

CYP3A4

55
Q

3A4 inducers increase ____

A

Has metabolism, increasing risk of pregnancy

56
Q

3a4 inducers:

A

anticonvulsants
antiretrovirals (HIV meds)
St John’s wort

Pharm Unit 5 (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions