Contraception Flashcards
What are the advantages and disadvantages of contraception?
Advantages: choice, control, family spacing, saves lives globally and cost effective
Disadvantages: changes in sexual habits, increased promiscuity, medical complications, cost
What factors need to be considered in a contraceptive consultation?
Health Age Desire for fertility Social/religious/ethical Education Compliance Cost
What are 4 methods of contraception?
Natural/physiological
Barrier (condoms)
Hormonal
Surgical
What are natural methods of contraception?
Rhythm method - avoid intercourse in the fertility window (4-5 days prior and 1-2 days after predicted ovulation), cheap and no side effects, good for religions, limits sexual activity, high failure rate and no STI protection
Coitus interruptus - penile withdrawal before ejaculation has significant failure rate and no STI protection
Lactation - regular and exclusive breastfeeding inhibits secretion of FSH by prolactin release so suppress HPO axis = no ovulation
What are barrier methods of contraception?
Condom
Diaphragm
Cervical cap
Sometimes may contain spermicide
What are advantages and disadvantages of condoms?
Cheap
Readily available
STI protection
Latex allergy
Can split
Sensation loss
What’s the LARC? It’s advantages and disadvantages
Long acting reversible contraception - copper IUD releases copper which is a spermicide and mechanically prevent implantation
Good for long term, amenorrhoea, decrease dysmenorrhoea
Decreased libido, irregular bleeding, cost, invasive
What are complications of the IUCD?
Expulsion
Perforation
Infection
Ectopic implantation
Side effects: bleeding, cramping
When would you use the IUCD?
Long lasting 1-12 years
Can’t be used as emergency contraception if implanted within 5 days of unprotected sex
What’s the deadline when you can have termination of pregnancy?
Up to 9 weeks - medication to induce termination
Up to 24/40 weeks legal to abort
After 9 weeks require surgery: vacuum aspiration up to 15 weeks and dilation/curettage over 15 weeks
Outline surgical sterilisation
Prevents sperm/egg interaction
Surgical interruption
Tubal ligation in female
Vasectomy in male
Counselling may be required
Invasive
Irreversible
Failures
What’s the basic point of the oral hormone contraceptives?
Synthetic steroid hormones that mimic functions of oestrogen and progesterone
What are the two types of oral contraceptive?
Combined: oestrogen and progrestogen
Progresterone only
What’s the MoA of the combined oral pill?
Synthetics in the pill act upon Oestrogen (ER1a and ERB) and Progesterone (PR-A and PR-B) receptors, acting as intracellular transcription factors
Hormones diffuse across cell membranes to reach intracellular receptors
Binding drives receptor activation via dissociation from HSP90
Active receptors dimerise -> influence gene expression
= suppress ovulation
What’s ovulation driven by and therefore how can contraceptives prevent ovulation?
Ovulation drives by endocrine dynamics
Timing of hormone secretion and activity
Can disrupt critical endocrine events required for ovulation