Contraception Flashcards
% unintended pregnancy - female sterilisation
0.5%
% unintended pregnancy - vasectomy
0.1%
% unintended pregnancy - progesterone only implant
0.05%
% unintended pregnancy - mirena
0.2%
% unintended pregnancy - Copper coil
0.8-0.6%
% unintended pregnancy - Depo injection
0.2 - 6%
% unintended pregnancy - COCP and POP
0.3- 9%
% unintended pregnancy - male condom
18 - 2%
% unintended pregnancy - female diaphragm
12 - 6%
UKMEC category 1
no restriction
UKMEC category 2
advantages outweigh theoretical risk
UKMEC category 3
theoretical or proven risks outweigh advantage
UKMEC category 4
unacceptable health risk
Which conditions contraindicate the use of certain contraceptives postpartum/breastfeeding (UKMEC 4)?
postpartum sepsis contraindicates the use of intrauterine devices
1-3 week postpartum + VTE risk - no cocp
Which contraceptives can be safely used postpartum and breastfeeding?
Progesterone only pill/depo/implant
When should cocp be avoided (UKMEC 3) postpartum/breastfeeding?
0-3 weeks post partum without VTE risk factors
3-6 weeks with risk factor of VTE
When should IUDs be avoided postpartum/breast feeding (UKMEC 3)
48-4weeks post partum (can be inserted in first 48 hours)
Regarding BMI, when should COCP be avoided?
BMI >/= 35
Which contraceptions are UKMEC 2 for organ transplant?
If uncomplicated - all are
If complicated it is not advisable to start IUD or COCP but progesterone only is UKMEC 2 and IUD can be continued if already present
Which contraceptives should be avoided (UKMEC 3) in patient with multiple cardiac risk factors?
Depo injection and COCP
Which contraception is contraindicated with impaired cardiac function?
COCP, the rest are fine to use
Which contraception is contraindicated in AF?
COCP, the rest are fine to use
Which contraceptions are best avoided in long QT and why?
Advisable not to start an IUD, risk of vasovagal due to cervical excitation leading to bradycardia and risk of cardiac event
Which contraceptions are UKMEC 3/4 with gestational trophoblastic disease?
All fine if BHCG levels not detectable
IUDs should be avoided if BHCG levels present and falling
IUDS contraindicated if BHCG levels elevated or there is malignant disease
Which contraceptions are UKMEC 3/4 with cervical cancer?
Awaiting treatment UKMEC 4 - do not start IUD Radical cervicectomy (Trachelectomy) - UKMEC 3 IUD
In active breast cancer, which contraceptions are contraindicated?
Everything except copper coil
In past breast cancer, which contraceptives are UKMEC 3?
everything except the copper coil
Regarding breast conditions, when should COCP be avoided?
starting in an undiagnosed breast lump/mass/symptoms
BRCA1/BRCA2 carriers
What is the UKMEC guidance on contraception in ovarian cancer?
All contraceptions safe to use
Which contraceptions are contraindicated with certain STIs?
UKMEC 4 IUD insertion of IUD in a symptomatic chlamydia or active gonorrhoea or in cervicitis or active PID, UKMEC 3 for insertion of IUD in asymptomatic chlamydia
When should you not insert an IUD in a HIV positive patient?
If CD4 count <200
Which contraceptive is UKMEC 3 in diabetes?
COCP if associated cardiovascular disease or diabetic retinopathy
In viral hepatitis, which contraceptive should be avoided?
Don’t start COCP in an acute flare
What dose difference between the progesterone IUD that lasts for 3 years and theIUD that lasts for 5 years?
3 years - 13.5mg
5 years - 58mg
What is the risk of having an IUD at <20 years?
Increased risk of expulsion
What are highest risk factors for IUD expulsion?
lactation and insertion within 36 weeks of birth
Decompensated liver disease - IUD
copper coil safe
mirena should be avoided as liver will find it difficult to metabolise progesterone
What dose is the progesterone only implant?
68mg
When should an IUD be avoided in liver disease?
copper coil safe
UKMEC3 for mirena in decompensated liver disease, hepatocellular adenoma and carcinoma
What dose of progesterone is in the POP?
350micrograms norehisterone
75micograms desogestrel
progesterone only contraception and bone mineral density
depo has slight increased risk of reduced bone mineral density, in women under 18 other methods should be considered first
Progesterone only contraception post abortion/breastfeeding/postpartum
All safe to use straight away
Although, non-breastfeeding women don’t require contraception until 21 days
Progesterone only contraception in smokers and high BMI
safe to use
Vascular disease (CHD/TIA/PVD/angina) which progesterone only contraception should be avoided?
DEpo injection, otherwise all fine to use in patients with uncomplicated hypertension
Which contraception is safe to use in ischaemic heart disease and stroke?
Copper coil
Which contraceptions should be avoided in IHD/stroke?
avoid continuing mirena/POP/implant if stroke or IHD develops
avoid depo UKMEC 4 with stroke/IHD
Which progesterone only contraception is UKMEC3 with unexplained vaginal bleeding?
implant and depo
POP = UKMEC 2
Active or past breast cancer - progesterone only contraceptives
Active - UKMEC 4 for all including mirena
Past- UKMEC 3 for all including mirena
STIs- progesterone only contraceptives
safe to use except mirena
HIV - progesterone only contraceptives
safe to use except mirena if CD4 count <200
Liver disease- progesterone only contraceptives
avoid (UKMEC3) if decompensated liver disease or hepatocellular adenoma or carcinoma (including mirena)
Cervical/endometrial/ovarian cancer - progesterone only contraceptives
safe to use whilst awaiting treatment
mirena is ukmec 4 for starting in endometrial cancer and ukmec 2 for continuing
Do not start mirena whilst awaiting cervical treatment
theoretical risk of POC with cervical cancer and prognosis
Oestrogen in COCP
Ethinylestradiol
When is COCP contraindicated postpartum?
0-6 weeks breastfeeding
0- <3 weeks with VTE risk factors
Should be avoided if additional VTE risk factors 0-6 weeks postpartum (UKMEC 3)
Safe to use after 6 weeks
COCP post abortion
safe to use
smoking and COCP
ukmec 4 - >35 years and smoking >15/d
ukmec 3 - >35 years and smoking <15/d or quit within the last year
BMI and COCP
> 35 = UKMEC 3
Complicated organ transplant + COCP
UKMEC 3
Multiple risk factors for CVD + COCP
UKMEC 3 (also depo - other POP incl. mirena = UKMEC 2)
HTN + COCP
UKMEC 3
Except BP >160/>100 or vascular disease = UKMEC 4
IHD or Stroke + COCP
UKMEC 4!
History of vte or current vte + COCP
UKMEC 4
First degree relative <45 years had VTE + COCP
UKMEC 3
Major surgery + prolonged immobilisation + COCP
UKMEC 4
Immobility + COCP
UKMEC 3
Thrombogenic mutations + COCP
UKMEC 4
complicated heart disease/impaired cardiac function/AF + COCP
UKMEC 4
Migraine + COCP
with aura (at any age) = UKMEC 4 5 years ago with aura = UKMEC 3 Migraine without aura starts whilst on COCP = UKMEC 3 to continue
Breast cancer + COCP
Active = UKMEC 4
Past = UKMEC 3
BRCA1/BRAC 2= UKMEC 3
Undiagnosed breast lump - can continue UKMEC 2 but shouldnt start UKMEC3
STIs + COCP
Safe
HIV + COCP
safe
Diabetes + COCP
UKMEC 3 if diabetic retinopathy or other cvd risk factors
Gallbladder disease + COCP
UKMEC 3 if medically treated or current symptomatic disease
Viral hepatitis + COCP
UKMEC 3 for starting COCP if active infection
Liver disease + COCP
UKMEC 4 for hepatocellular adenoma and carcinoma and for decompensated liver disease
SLE + COCP
UKMEC 4 if anti-phospholipid antibodies present
When can copper IUD be used for emergency contraception?
0-120hours
Or within 5 days of ovulation
When can oral emergency contraception be used?
Ullipristal acetate within 120 hours
Levenorgesterel within 72 hours 1.5mg