Contraception Flashcards
Methods of Contraception
Natural family planning, Barrier methods (e.g., condoms), Combined contraceptive pills, Progestogen-only pills, Coils (copper or Mirena), Progestogen injection, Progestogen implant, Surgery (sterilisation or vasectomy).
Emergency Contraception
Available after unprotected intercourse but should not be used as a regular method.
UK Medical Eligibility Criteria
Categories to assess risks of contraceptive methods: UKMEC 1 (minimal risk), UKMEC 2 (benefits > risks), UKMEC 3 (risks > benefits), UKMEC 4 (unacceptable risk).
Effectiveness Explanation
Effectiveness refers to the likelihood of avoiding pregnancy. The combined oral contraceptive is 99% effective; only abstinence is 100% effective.
Perfect vs Typical Use
Effectiveness can vary between perfect and typical use, especially with user-dependent methods like pills and barrier methods. Long-acting methods like coils, implants, and surgery are less user-dependent.
Natural Family Planning Effectiveness
Perfect Use: 95-99.6%, Typical Use: 76%
Condoms Effectiveness
Perfect Use: 98%, Typical Use: 82%
Combined Oral Contraceptive Pill Effectiveness
Perfect Use: >99%, Typical Use: 91%
Progestogen-Only Pill Effectiveness
Perfect Use: >99%, Typical Use: 91%
Progestogen-Only Injection Effectiveness
Perfect Use: >99%, Typical Use: 94%
Progestogen-Only Implant Effectiveness
Perfect Use: >99%, Typical Use: >99%
Coils Effectiveness
Perfect Use: >99%, Typical Use: >99%
Surgery Effectiveness
Perfect Use: >99%, Typical Use: >99%
Breast Cancer Risk
Avoid hormonal contraception; use copper coil or barrier methods.
Cervical/Endometrial Cancer Risk
Avoid intrauterine systems like Mirena coil.
Wilson’s Disease Risk
Avoid using the copper coil.
Contraindications for Combined Pill
Avoid with uncontrolled hypertension, migraine with aura, history of VTE, smoking over age 35, prolonged immobility, vascular disease, liver issues, lupus with antiphospholipid syndrome.
Older Women Considerations
Contraception needed for 2 years after last period (under 50) or 1 year (over 50). HRT does not prevent pregnancy.
Progestogen Injection in Older Women
Stop before age 50 due to osteoporosis risk.
Contraception for Amenorrhoeic Women
Continue until FSH > 30 IU/L (2 tests, 6 weeks apart) or until 55 years old.
Contraception for Women Under 20
Combined and progestogen-only pills are safe. Implants are UK MEC 1. Injections are UK MEC 2 due to bone density concerns. Coils are UK MEC 2 (risk of expulsion).
Contraception After Childbirth
No contraception needed for 21 days post-birth. Use condoms with combined pill (7 days) or progestogen-only pill (2 days).
Lactational Amenorrhea
Over 98% effective as contraception if fully breastfeeding and amenorrhoeic for up to 6 months.
Progestogen-Only Methods Post-Birth
Safe during breastfeeding, can be started any time after birth.
Combined Pill Post-Birth
Avoid during breastfeeding before 6 weeks postpartum (UKMEC 4), use with caution after 6 weeks (UKMEC 2).
Copper Coil Post-Birth
Can be inserted within 48 hours or after 4 weeks (UKMEC 1). Avoid insertion between 48 hours and 4 weeks (UKMEC 3).
TOM TIP
Combined pill should not start before 6 weeks in breastfeeding women. Progestogen-only pill or implant can start any time post-birth.
What does the combined oral contraceptive pill (COCP) contain?
It contains a combination of oestrogen and progesterone.
How effective is the combined pill with perfect use?
More than 99% effective.
How effective is the combined pill with typical use?
About 91% effective.
Up to what age is the COCP licensed for use?
Up to the age of 50 years.
What are the three mechanisms by which the COCP prevents pregnancy?
Prevents ovulation, thickens cervical mucus, and inhibits proliferation of the endometrium.
What is the primary mechanism of action of the COCP?
Preventing ovulation.
How does progesterone in the COCP affect cervical mucus?
It thickens the cervical mucus, making it harder for sperm to penetrate.
What is the effect of progesterone on the endometrium in COCP users?
It inhibits proliferation of the endometrium, reducing the chance of successful implantation.
How do oestrogen and progesterone affect the hypothalamus and anterior pituitary?
They provide negative feedback, suppressing the release of GnRH, LH, and FSH.
Why is ovulation prevented when using COCP?
The suppression of LH and FSH prevents ovulation from occurring.
What happens to the endometrial lining when the COCP is stopped?
The lining breaks down and sheds, leading to a “withdrawal bleed.”
Is a withdrawal bleed considered a menstrual period?
No, it is not considered a menstrual period.
What can occur with extended use of COCP without a pill-free period?
“Breakthrough bleeding” can occur.
What are the two types of COCPs?
Monophasic pills and multiphasic pills.
What is a monophasic pill?
A pill containing the same amount of hormone in each pill.
What is a multiphasic pill?
A pill containing varying amounts of hormone to match natural hormonal changes.
What is an example of an everyday formulation COCP?
Microgynon 30 ED, which contains seven inactive pills for daily use.
How do different COCP formulations vary?
They differ in the amount of oestrogen (ethinylestradiol) and type of progesterone.
What does Microgynon contain?
Ethinylestradiol and levonorgestrel.
What does Loestrin contain?
Ethinylestradiol and norethisterone.
What does Cilest contain?
Ethinylestradiol and norgestimate.
What does Yasmin contain?
Ethinylestradiol and drospirenone.
What does Marvelon contain?
Ethinylestradiol and desogestrel.
Which COCPs are recommended first-line according to NICE guidelines (2020)?
Pills with levonorgestrel or norethisterone, such as Microgynon or Loestrin.
Why is Yasmin considered first-line for premenstrual syndrome (PMS)?
It contains drospirenone, which has anti-mineralocorticoid and anti-androgen activity, helping with bloating, water retention, and mood changes.
How can the COCP be more effective for premenstrual syndrome?
By using it continuously rather than in a cyclical pattern.
What is Dianette used for?
Treating acne and hirsutism due to its anti-androgen effects.
Why is Dianette usually stopped after three months of acne control?
It has a higher risk of venous thromboembolism (VTE).
What are the three common regimes for taking the combined pill?
21 days on and 7 days off, 63 days on and 7 days off (“tricycling”), and continuous use without a pill-free period.
What are common side effects of the COCP?
Unscheduled bleeding, breast pain, mood changes, headaches, hypertension, and a small increased risk of VTE, breast, and cervical cancer.
What benefits does the COCP provide?
Effective contraception, rapid return of fertility, improvement in premenstrual symptoms, menorrhagia, dysmenorrhoea, and reduced risks of endometrial, ovarian, and colon cancer.
What are some contraindications for using the COCP?
Uncontrolled hypertension, migraine with aura, history of VTE, heavy smoking over age 35, major surgery with immobility, vascular disease, ischaemic heart disease, liver issues, and certain autoimmune conditions.
What does UKMEC 3 indicate regarding the COCP?
It means risks generally outweigh the benefits, such as when BMI is above 35.
When should you use additional contraception if starting the pill after day 5 of the menstrual cycle?
For the first 7 days of consistent pill use.
What should you do when switching between different COCPs?
Finish one pack, then immediately start the new pack without a pill-free period.
What is needed when switching from a traditional POP to a COCP?
7 days of extra contraception, like condoms, is required.
When switching from desogestrel to a COCP, is extra contraception needed?
No, because desogestrel inhibits ovulation.
What should you check during a consultation for prescribing the COCP?
Contraceptive options, contraindications, adverse effects, pill instructions, factors affecting efficacy, and any safeguarding concerns.
How should you assess contraindications for the COCP?
By discussing age, BMI, blood pressure, smoking status, medical history, and family history.
What is considered a missed pill for COCP users?
When a pill is more than 24 hours late (48 hours since the last pill was taken).
What should you do if one pill is missed (less than 72 hours since the last pill)?
Take the missed pill as soon as possible, even if it means taking two pills on the same day. No extra protection is needed if other pills are taken correctly.
What should you do if more than one pill is missed (more than 72 hours)?
Take the most recent missed pill as soon as possible, use extra contraception for 7 days, and consider emergency contraception if unprotected sex occurred in the first 7 days.
When is emergency contraception needed if more than one pill is missed?
If it is during days 1-7 and unprotected sex occurred.
How should vomiting or diarrhoea be managed in COCP users?
It is treated as a “missed pill” day, and additional contraception may be required.
When should the COCP be stopped before a major operation?
4 weeks before, to reduce the risk of thrombosis.
What is the progestogen-only pill (POP)?
The progestogen-only pill (POP) is a type of contraceptive pill that contains only progesterone.
How effective is the POP?
The POP is more than 99% effective with perfect use but less effective with typical use (91%).
What is the main difference between the POP and combined pills?
The POP is taken continuously, unlike the cyclical combined pills.
What is the main contraindication for the POP according to UKMEC?
The only UKMEC 4 criterion for the POP is active breast cancer.
What are the two types of POP?
- Traditional progestogen-only pill (e.g., Norgeston or Noriday)
How late can the traditional POP be taken?
The traditional POP cannot be delayed by more than 3 hours; taking it more than 3 hours late is considered a “missed pill.”
How late can the desogestrel-only pill be taken?
The desogestrel-only pill can be taken up to 12 hours late and still be effective; taking it more than 12 hours late is considered a “missed pill.”
What are the main mechanisms of action for traditional progestogen-only pills?
- Thickening the cervical mucus
How does desogestrel primarily work?
Desogestrel works mainly by inhibiting ovulation, thickening cervical mucus, altering the endometrium, and reducing ciliary action in the fallopian tubes.
When should the POP be started for immediate protection?
The POP should be started on day 1 to 5 of the menstrual cycle for immediate protection.