Contraception Flashcards
A 35-year-old woman presents to her GP to talk about contraception options. She has recently started a new relationship but is unsure if she may want children in the future. When you question her she has no problems with needles or insertion procedures. However, she struggles with heavy painful periods and dyspareunia and asks which option would be best for this. She has a past medical history of hypertension that runs in her family. There is no other relevant past medical or family history. An STI screen is negative.
What form of contraception would be best for this patient?
A. Combined oral contraceptive pill
B. Intrauterine device (IUD)
C. Intrauterine system (Mirena coil)
D. Progesterone-only implant
E. Progesterone-only pill
Answer: C
-An intrauterine system (e.g. Mirena) is particularly useful if patients have underlying medical problems (e.g. hypertension) +/- menstrual problems such as heavy periods
-1/3: lighter periods, irregular periods, no periods
What are UKMEC3 conditions?
-more than 35 years old and smoking less than 15 cigarettes/day
-BMI > 35 kg/m^2*
-family history of thromboembolic disease in -first degree relatives < 45 years
-controlled hypertension
-immobility e.g. wheel chair use
-carrier of known gene mutations associated with breast cancer (e.g. BRCA1/BRCA2)
-current gallbladder disease
What are UKMEC4 conditions?
-Migraine with aura
-Current breast cancer
-Significant VTE risk factors (e.g. previous VTE, thrombogenic mutations, previous stroke, SLE, atrial fibrillation, age >35 and smoking >15 -cigarettes daily)
-Cardiovascular risk factors: hypertension (>160mmHg systolic or >100mmHg diastolic), history of ischaemic heart disease
-Severe liver disease
-breastfeeding <6 weeks
A 23-year-old female attends her pharmacy as she is concerned that she may need the emergency contraceptive pill.
She tells you that she had unprotected sex with her long-term partner 3 days ago and didn’t think about contraception, as she gave birth to a baby girl only 2 weeks ago. She is formula-feeding her baby.
What is the most appropriate advice?
A. Copper coil
B. Levonorgestrel (Levonelle)
C. Mirena coil
D. No action required
E. Ulipristal acetate (EllaOne)
D: No action needed. Post-partum, women only require contraception 21 days from giving birth.
As sperm can survive in the vagina for up to 7 days, and the earliest date of ovulation after giving birth is 28 days postpartum, no contraception is needed until day 21. As this patient is 14 days postpartum, she does not need emergency contraception.
Contraceptives - time until effective (if not first day period):
a) IUD
b) POP
c)COC, injection, implant, IUS
a) Immediately
b) 48 hours (2 days); takes 48 hours for progesterone to thicken cervical mucus
c) 7 days: takes this long for COCP to inhibit ovulation
what is a safe long-term choice to use in patients taking enzyme-inducers?
- Depo-Provera injection, 2. IUS, 3. IUD not affected by enzyme inducers) (The Nexplanon implant is known to be affected by enzyme inducers and therefore should be avoided.
Other combined hormonal preparations such as the patch and the NuvaRing are also likely to be affected by her medication
COCP/POP affected by enzyme inducers
A 32-year-old woman attends to have her copper intrauterine device (IUD) removed. She is currently on day 4 of her regular 30-day menstrual cycle. Following the removal of the IUD, she would like to start the combined oral contraceptive pill (COCP). There are no contra-indications to the COCP.
What is the most appropriate next step in the management of this patient?
A. Start the combined oral contraceptive pill today, no further contraceptive is required
B. Use barrier contraception for 2 more days and start the combined oral contraceptive pill on day 7 of the menstrual cycle
C. Start the combined oral contraceptive pill today and use barrier contraception for 5 days
D. Wait for 5 days and then start the combined oral contraceptive pill
E. Start the combined oral contraceptive pill today and use barrier contraception for 7 days
A. Start the combined oral contraceptive pill today, no further contraceptive is required
-When switching from an IUD to COCP no additional contraception is needed if removed day 1-5 of cycle
- If the patient is unable to start the COCP today and she starts it from day 6 onwards (ie after day 5), barrier contraception is required for 7 days.
why is BMI >35 relevant?
Her BMI of >35 is a relative contraindication (UKMEC 3) for the combined hormonal contraceptive options including the pill, patch, and NuvaRing.
A 32-year-old female requests emergency contraception. She had unprotected sexual intercourse 28 hours ago and is not using any regular contraception. She has a diagnosis of obesity, severe asthma and uterine fibroids with distortion of the uterine cavity. Which emergency contraception option & why?
A. Ethinylestradiol
B. Levonorgestrel (standard dose)
C. Levonorgestrel (double standard dose)
D. Norethisterone
E. Ulipristal
F. Copper intrauterine device
G. Mirena intrauterine system
H. She has presented too late for emergency contraception
B. Levonorgestrel (double standard dose)
The dose should be doubled to 3mg levonorgestrel for those with a BMI >26 kg/m2 or weight over 70kg. As this patient has a diagnosis of obesity we know her BMI is 30 kg/m2 or higher. Therefore, the answer is levonorgestrel 3mg.
Ulipristal should be avoided due to her history of severe asthma.
Norethisterone and ethinylestradiol are not used as an emergency contraceptive.
Intrauterine devices are not recommended in patients with distortion of the uterine cavity secondary to fibroids.
A 41-year-old female called this morning to request emergency contraception. She had unprotected sexual intercourse 48 hours before calling and is not using any regular contraception. Currently, she is breastfeeding. There is no medical history of note and she weighs 55 kg. She declined an intrauterine device and you prescribed an emergency hormonal contraception however she calls during your afternoon clinic to say she vomited one hour after taking this.
A. Ethinylestradiol
B. Levonorgestrel (standard dose)
C. Levonorgestrel (double standard dose)
D. Norethisterone
E. Ulipristal
F. Copper intrauterine device
G. Mirena intrauterine system
H. She has presented too late for emergency contraception
Vomiting occurs in around 1% of patients who take levonorgestrel. If vomiting occurs within 3 hours then the dose should be repeated. She already had emergency contraception therefore repeat it (standard dose)
Breastfeeding should be delayed for one week after taking ulipristal. There are no such restrictions with levonorgestrel and so levonorgestrel is more appropriate for this patient.
A 19-year-old woman presents to your surgery after engaging in unprotected sexual intercourse (UPSI) 4 days ago. She is not on any contraception and is worried she will become pregnant. This woman has a past medical history of major depression and severe asthma, for which she takes 25mg OD sertraline, 200 micrograms salbutamol inhaler PRN, beclomethasone 400 micrograms BD and formoterol 12 micrograms BD.
She is on day 25 of a 35 day cycle.
What is the most appropriate intervention to prevent this woman becoming pregnant?
A. Intra-uterine device
B. Levonorgestrel
C. Mirena coil
D. No intervention needed
E. Ulipristal (EllaOne)
A. IUD
The answer is the intra-uterine device aka the copper coil. This woman is presenting 4 days (96 hours) after UPSI. The levonorgestrel pill is only effective up to 72 hours after UPSI, so is not appropriate. Ulipristal is effective up to 120 hours after UPSI, but is cautioned due to this patient’s severe asthma, thus the IUD would be the most appropriate in this scenario.
If period is 35 days, then ovulation should occur at 21 days (luteal phase=14 days fixed. Therefore, ovulation=cycle length-14 days)
IUD insertion:
-must be inserted within 5 days of UPSI, or
-if a woman presents after more than 5 days then an IUD may be fitted up to 5 days after the likely ovulation date
When can IUD/IUS be inserted post-partum?
The intrauterine device or intrauterine system can be inserted within 48 hours of childbirth or after 4 weeks (28 days)
What are the 2 types of POP (with names):
- Traditional progestogen-only pill (eg Micronor, Noriday, Nogeston, Femulen)
- Desogestrel-only pill (e.g. Cerazette)
A 27-year-old female presents to her GP as she missed her desogestrel contraceptive pill (progestogen only) this morning and is unsure what to do. She normally takes the pill at around 0900 and it is now 1430. What advice should be given?
A. Emergency contraception should be offered
B. Perform a pregnancy test
C. Take missed pill as soon as possible and omit pill break at end of pack
D.Take missed pill now and no further action needed
E.Take missed pill now and advise condom use until pill taking re-established for 48 hours
42%
D.Take missed pill now and no further action needed
As desogestrel has a 12-hour window this patient should take the pill now with no further action being needed
What are the missed pill rules for POP pills (traditional vs desogestrel)?
What are the missed pill rules for COCP (if in week 1, 2 or 3)
-if pills are missed in week 1 (Days 1-7): emergency contraception should be considered if she had unprotected sex in the pill-free interval or in week 1
-if pills are missed in week 2 (Days 8-14): after seven consecutive days of taking the COC there is no need for emergency contraception*
-if pills are missed in week 3 (Days 15-21): she should finish the pills in her current pack and start a new pack the next day; thus omitting the pill free interval
What can be done to mitigate heavy, unscheduled bleeding (a side effect of the contraceptive implant (Nexplanon)?
3 months of COCP (makes periods lighter & more regular)
A 22-year-old student consults her GP as she has some questions about the combined oral contraceptive pill. After her own background reading she is struggling to understand what the risk of an unplanned pregnancy would be if she were to start taking this form of contraception. Assuming the Pearl Index of the combined oral contraceptive pill is 0.2, how will you explain the failure rate of this form of contraception if used correctly?
A. For every thousand women using this form of contraception for one year, two would become pregnant
B. For every thousand women using this form of contraception for ten years, two would become pregnant
C. For every hundred women using this form of contraception for one year, two would become pregnant
D. 0.2% of women using this form of contraception become pregnant
E. If used as the sole form of contraception, the risk of an unplanned pregnancy after each episode of coitus is 0.2%
A. For every thousand women using this form of contraception for one year, two would become pregnant
-The Pearl Index describes the number of pregnancies that would be seen if one hundred women were to use the contraceptive method in question for one year. Therefore in the question, assuming the Pearl Index is 0.2 and the medication is adhered to perfectly, we would expect to see 0.2 pregnancies for every hundred women using the pill for one year - or 2 for every thousand.