Contact Urticaria

Question 1

Risk factor for Contact urticaria?

Answer 1

• Atopy

Question 2

Pathogenesis of immunologic contact urticaria?

Answer 2

• allergen-specific IgE on mast cells–> histamine release (possible anaphylaxis)

Question 3

What are the most common causes of immunologic contact urticaria?

Answer 3

• raw vegetables/meats: (POTATO is #1 and often a/w asthmatic response)

Question 4

latex contact urticaria is immunologic or non-immunologic?

Answer 4

• immunologic

Question 5

Latex contact urticaria presents as?

Answer 5

• itching and swelling of hands within minutes of applying gloves.
• aerosolized glove powder can induce anaphylaxis

Question 6

50% of latex allergies have cross reactions with what other things?

Answer 6

BACK Passion:

- banana, avocado, chestnuts, kiwi, Passion fruit

Question 7

Non-immunologic contact urticaria is more or less frequent that immunologic?

Answer 7

• much more frequent

Question 8

Non-immunologic contact urticaria number 1 cause is:

- what are some other causes?

Answer 8

• Stinging nettles (Urticaceae)

- others: jelly fish, caterpillars

Question 9

Non-immunologic contact urticaria is caused by agents that lead to ______

Answer 9

• direct release of histamine, acetylcholine and serotonin

Question 10

Tx of contact urticaria?

Answer 10

• antihistamines

- if anaphylaxis then add epinephrine and supportive care