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2. Cardiovascular Flashcards > Constituents of Blood > Flashcards

Constituents of Blood Flashcards

1
Q

What is the lifespan of a RBC?

A

120 days

make 2 mill a second

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2
Q

What is a hormonal growth factor?

A

Stimulate precursor stem cells to proliferate and differentiate

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3
Q

What is the hormone growth factor for Red blood cells?

Where is the hormone made?

A

Erythropoietin

In the kidneys

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4
Q

What is the lifespan of a White blood cell/leukocyte?

What is the hormonal growth factor in WBC?

A

6-10 hours
granulocyte colony stimulating factor
G-CSF

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5
Q

What is the lifespan of platelets?

What is the hormone growth factor of platelets?

A

7-10 days

thrombopoetin (Tpo)

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6
Q

Both RBCs and platelets are…

A

anucleate (have no nucleus)

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7
Q

How many L of blood do we have?

A

5 Litres

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8
Q

What are the 2 phases of blood?

A 
Fluid Component (55% - plasma)
Cellular component (45% - RBC (forms 99% of blood cells) , WBC & Platelets)
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9
Q

What is plasma without clotting factors called?

A

Serum

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10
Q

What is the volume of RBC in the blood called and its normal level?

A

Haematocrit
normal=0.45
RBC : Total blood volume

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11
Q

What is the precursor to all blood cells?

A

Haematocytoblast (pluripotent stem cell)

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12
Q

What is the formation of blood cells from haematocytoblasts called?

A

Haematopoesis

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13
Q

What do Haematocytoblasts differentiate into? (5)

A 
Lymphoblast
Monoblast
Megakaryoblast
Myeloblast
Proerythroblast
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14
Q

what does proerythroblast differentiate into?

A

erythrocytes

RBCs

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15
Q

What do myeloblasts differentiate into?

A

progranulocyte into

basophils, eosinophils, neutrophils

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16
Q

What do lymphoblasts differentiate into?

A

B & T Lymphocytes

17
Q

What do monoblasts differentiate into?

A

Monocytes

18
Q

What do megakaryoblasts differentiate into?

A

Megakaryocytes then

Platelets (thrombocytes)

19
Q

What is haemopoiesis?

A

the process of the production of blood cells and platelets which continues through life

20
Q

In adults and in embryonic life/early infancy, where does haemopoiesis occur?

A

adult - bone marrow

embryo - occur at other sites

21
Q

Where are the precursor cells of RBCs located, in adults, children and utero specifically?

A

bone marrow

adults - axial skeleton; skull, ribs, spine, pelvis, long bones

children - in all bones

utero - in yolk sac, liver and spleen

22
Q

Where are Precursor cells not found?

If they are found there, what is it a sign of?

A

Not found in the blood

if they are, its a sign of leukaemia

2. Cardiovascular Flashcards (18 decks)

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