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Pharm 2 > Constipation, nausea, vomiting > Flashcards

Constipation, nausea, vomiting Flashcards

1
Q

psyllium MOA

A

bulking agent…increase stool weight

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2
Q

psyllium Ae

A

flatulence

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3
Q

Lactulose/ sorbitol MOA

A

osmotic laxatives..synthetic dissacharide increasing osmotic pressure

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4
Q

Lactulose/ sorbitol AE

A

bloating cramps, flatulence

“sickly sweet”

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5
Q

magnesium citrate, magnesium hydroxide, sodium phosphate MOA and indications

A

indications: mag citrate and sod phosphate for bowel preps
mag hydroxide for normal constipation
osmotic laxative…also Mg stimulates cholecystokinin

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6
Q

magnesium citrate, magnesium ydroxide, sodium phosphate Contra and AE

A

contra: bowel obstruction, renal failure…careful with CHF patients
AE: dehydration, ACUTE PHOSPHATE NEPHROPATHY (calcium phosphate crystals in kidney tubules)

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7
Q

polyethylene glycol MOA and indications

A

osmotic laxative….high doses used for bowel prep…low for constipation

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8
Q

Senna/ Biscodyl MOA and indications

A

stimulant laxatives
Senna: stimulates myenteric plexus
Bisacodyl: parasympathetic stimulation
indications: constipation

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9
Q

Senna/ Bicodyl AE

A

cramping, melanosis coli

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10
Q

Docusate MOA

A

degergent laxatives

increases penetration of fluid into stool, softens it

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11
Q

Glycerin and mineral oil suppository / enima MOA

A

lubricants

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12
Q

mineral oil AE

A

never give orally ot sick patient…lipid pneumonitis if aspirated

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13
Q

Prochloroperazine MOA and indications

A

dopamine receptor antagonist in CTZ
blocks vagus nerve
indications: opiod nausea/ vomiting, also
GI disorders, inflammation, infection

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14
Q

Prochlorperazine AE

A

Parkinson’s like syndromes and freezing (ie lockjaw”

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15
Q

Metaclopramide MOA and indications

A

dopamine receptor antagonist in CTZ

also: sitmulates motility in upper GI
indications: Chemo induced nausuea / vomiting…also gastric stasis

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16
Q

Metaclopramide AE

A

parksinon’s like syndrome and freezing (ie lockjaw)

17
Q

Odansetron MOA and indications

A

serotonin receptor antagonist…not sure if central peripheral or both
indications: chemo, radiation, post op nausea/ vomiting

18
Q

Odansetron AE

A

QT prolongation, headache

19
Q

Promethazine MOA and indications

A

Histamine receptor antagonist

indication: mostion sickness, inner ear problems

20
Q

Promethazine AE

A

Sedation

21
Q

Scopalomine MOA indications

A

cholinergic antagonist

indication: motion sickness

22
Q

scopalomine AE

A

confusion, urinary retention, glaucoma, dry mouth

23
Q

Prednisone/ dexamethasone MOA and indications

A

corticosteroids…nausea from increased intracranial pressure

24
Q

Lorazepam/ diazepam MOA and indications

A

benzos..from anticipatory nausea/ vomiting

Pharm 2 (5 decks)

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