connective tissure

Question 1

Dermis

Answer 1

the papillary layer: loose CT
the reticular layer: dense CT

Question 2

hypodermis

Answer 2

loose CT
apidocytes

Question 3

Function of connective tissue

Answer 3

framwork let epithelial rest on
nerve and muscle embeded
carry nerves and blood vessels that provide innervation and blood supply to the epidermis and other epithelia
provides support and a connecting framework to other tissues of the body
communicaiton and transport

Question 4

CT derived from

Answer 4

mesenchyme

Question 5

Component of CT

Answer 5

different cells and extracellular matrix (extracellular fibers and amorphous ground substances)

Question 6

types of CT

Answer 6

loose
dense (irregullar regullar)
supporting CT. (ex. bone cartilage)
CT. with special properties (ex. bone marrow)

Question 7

when fibrocyte go to fibroblast

Answer 7

wound healing
fibrocyte heterochromatin

Question 8

Mesenchymal cell

Answer 8

from mesoderm of the embryo
very active
differentiate to all kinds of CT cells

Question 9

Common cells in CT

Answer 9

fibroblast: secrete collagen and other ECM
adopocyte: store fat
Mast cells, macrophages, lymphocytes, plasma cells: immune functions

lymphocyte: humoral response, secret immunoglobulin
mast cell: allergic reaction secrete hepatin and histamine
plamic cell: produce antibody
macrophage: phagocyte

Question 10

ground substrance composition

Answer 10

water, glycosaminoglycans, proteoglycans, glycoproteins

fiberonectin (structural glycoprotein)
proteoglycan
GAGs:
1. chondroitin SO4 +core protein
2. dermantan SO4+core protein
3. Heparan SO4+core protein
4. Keratan SO4+core protein

in bone: have minerals
in blood: is fluid (plasma)

Question 11

fibers

Answer 11

collagen: confer strangth and flexibility
elastic finber: confer resistancy (elastin)

Question 12

collagen fibers

Answer 12

Type I – dermis, tendon, bone
Type II –cartilage
Type III – reticular fiber
Type IV – BM
Type V – fetal tissue, only in embryo

Question 13

collagen type I made

Answer 13

alpha 1 and 2 gene

3 preprocollagen peptide in Rough ER
hydroxylation of lysine and proline residues
attach suger
assemble the procollagne molecule (triple helix)

golgi packing and secretion

extracelllular space: procollagen peptidases: cleave the tripe helix
left with tropocollagen
self aggregate to microfibril, collagen fibril adn finally collagen fiber

Question 14

cartilage and bone

Answer 14

support mechnical stress without distortion and also provide support to adjacent soft tissue