Connective tissues - Lymphatic system Flashcards
Fiber forming cells
Fibroblasts
Monocytes outside the circulatory system; differentiated monocytes; they are formed in the bone marrow
Macrophages
Pulp is a connective tissue or not?
Connective tissue
The space where we can find the osteoclast/depression
Howship’s Lacunae
Function of macrophage
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location: Connective tissues, lymphoid organs, lungs, bone marrow, pleural and peritonea cavities
Function of Kupffer
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location: Liver (Perisinusoidal)
Function of Microlagia
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location: CNS
Function of Dust cells/Alveolar macrophages
(Heart failure cells)
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location: Pulmonary alveoli of lungs
Function of sinus histiocytes
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location; Lymph nodes
Function of Histiocytes (Tissue Macrophages)
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location; Connective tissue
Function of Langerhan’s cells (Stratum spinosum)
(Mononuclear phagocyte system)
-Production of cytokines, chemotactic factors, and inflammatory molecules, Antigen-presenting cells.
-Location; Epidermis
Function of Dendritic cells
(Mononuclear phagocyte system)
-Antigen - presenting cells
-Location; Lymph nodes, spleen
Function of Osteoclast
(Mononuclear phagocyte system)
-Digestion bone
-Location: Bone
Function of Epitheloid cells and langhans giant cells (Fused epitheloid cells)
-DIgestion of foreign bodies
-Location: Granuloma (Ex. TB)
Function of Hofbauer cells
-Prevents transmission of pathogens from mother to fetus
-Location: Placenta
Function of Intraglomerular mesangial cells
-Regulates glomerular filtration
-Location: Kidney
-They recognize immediately the harmful organisms
Antigen-Presenting cels (APC)
-They are presenting the antigen to the other white blood cells to respond the immune system
Examples of Antigen-presenting cells
-Macrophages
-Dendritic cells
-B cells
Fat cell or adipose cells
Adipocytes
“Signet ring appearance”
Adipocytes
They don’t have direct blood supply and nerve supply
( No pain, Poor regenerative properties)
Cartilage
Growth within the tissue; happens only when a cartilage is young and pliable, during childhood and adolescence.
Interstitial growth
Chondrogenesis
Cartilage formation
Growth at the outer surface; continuous through adolescence.
This is due to addition of matrix at the surface of tissue
Appositional growth
Cartilage type (CHEF)
Cartilage type (CHEF)
H - hyaline cartilage
E - Elastic cartilage
F - Fibrocartilage
Made up of chondrocytes + few collagen fibers
*Most numerous; weakest
Hyaline cartilage
Made up of chondrocytes + elastic fibers
*Least common type
Elastic cartilage
Made up of chondrocytes + thick collagen fibers
*Strongest type
Fibrocartilage
Example location of Hyaline cartilage
*Ends of bones that forms joint
*Nose
*fetal skeleton
*Trachea
*Bronchial tree
*Synchondrosis
Example location of elastic cartilage
*Pinna (Auricle) ear
*Epiglottis
*Eustachian tube
Example location of Fibrocatilage
*Meniscus of knee joint or TMJ
*Symphysis joints
1. Symphysis menti
2. Symphysis pubis
3. Manubriosternal join
4. Intervertebral disc
Closes the larynx when swallowing preventing food in airway
Epiglottis
Connects middle ear to the nasopharynx
Eustachian tube
Between manubrium and body of sternum
Manubriosternal joint
Manubriosternal joint aka?
Sternal angle or “Angle of louis”
Rib that is not palpable because of the presence of clavicle
Rib #1
Removal of air/fluid from pleural cavity
Thoracentesis
-Aka woven bone or immature bone
-Randomly arranged cells and fibers
-less calcified
Primary bone
-Aka Lamellar bone or immature bone
-parallel bundles of collagen
-Heavily calcified (Matured)
-Has 2 subtypes: spongy bone and compact bone
Secondary bone
Aka cancellous bone or trabecular bone
Made up of trabeculae
Spongy bone
Gaps in between the bone
It houses bone marrow tissues
Trabeculae
Strongest type of bone
Functional unit is known as Haversian system or Osteon
Compact bone
Outer to protect spongy bone
Compact bone
Growth WITHIN the tissue
Interstitial
Lengthening of bones
Interstitial
Widening of bone
Appositional
“ILAW”
Interstitial = lengthening of bones
Appositional = widening only
What structure is seen at the central portion of osteon?
Haversian canal
-Plasma 55% mostly water around 95% and other substances
-Formed elements 45% blood cell
Blood
Growth on EXTERNAL surface
Appositional