Connective Tissues Flashcards

1
Q

What are the purposes of connective tissues? Where is it found?

A
  • Bind and support (e.g. ligaments, tendons, bones)
  • Protect (e.g. bones and cartilage, adipose tissue)
  • Store and insulate (e.g. adipose tissue)
  • Transport (e.g. blood)

Connective tissue is found to varying degrees in the different organs (e.g. lots in bones and skin, but very little in the brain)

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1
Q

What are connective tissues composed of? (3)

A

1) Specialized cells: fibroblasts, macrophages, mast cells, plasma cells, adipocytes, and white blood cells

2) Extracellular matrix: makes up the bulk of connective fibrous proteins (collagen and elastin), ground substance (proteoglycans, which are produced by fibroblasts)

3) Tissue fluid: ground substance; clear, colourless viscous fluid, and proteglycans

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2
Q

What is the main characteristic of connective tissue?

A

Characterized by an intricate extracellular matrix that has large amounts of collagen fibres (provide tensile strength), and elastin fibres (provides resiliency)

Connective tissues can be vascular (with blood vessels) or avascular (without blood vessels). Avascular tissue such as tendons and ligaments heal very poorly as opposed to vascular bone

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3
Q

What are the (6) general categories of connective tissue?

A

1) Loose connective tissue
2) Dense connective tissue
3) Cartilage
4) Bone
5) Blood
6) Lymph

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4
Q

Why do avascular tissues heal slower/more poorly than vascular tissue?

A

Without blood vessels, avascular tissues rely on the diffusion of nutrients and oxygen, which is slower

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5
Q

What are connective tissue proper?

A

Includes those connective tissues with many types of cells and extracellular fibres in a syrupy ground substance. Cells include: fibroblasts, adipocytes, macrophages, stem cells)

1) Loose (aar)

fibres create loose, open framework
-areolar tissue
-adipose tissue
-reticular tissue

2) Dense (dde)

fibres densely packed
-dense regular tissue
-dense irregular tissue
-elastic

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6
Q

What are fluid connective tissues?

A

Fluid connective tissues have distinct populations of cells suspended in a watery matrix that contains dissolves proteins

1) Blood: flows within cardiovascular system

2) Lymph: flows within lymphatic system

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7
Q

What are supportive connective tissues?

A

Support connective tissues differ from connective tissue proper in having less diverse cell populations and a matrix containing much more densely packed fibres

supporting connective tissues protect soft tissues and support the weight of part or all of the body

1) Cartilage: solid, rubbery matrix

-hyaline cartilage
-elastic cartilage
-fibrous cartilage

2) Bone: solid, crystalline matrix

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8
Q

What is areolar tissue?

A

Contains both collagen and elastin fibres and reticular, loosely arranged (e.g. between skin and muscle)

forms the basement membrane for epithelia tissue and mucous membranes

this tissue swells with the release of fluid from the blood stream, a condition called edema

fibres: reticular fibres, collagen fibres, elastic fibres
fixed cells: melanocytes, macrophages, mast cells, fibroblasts, adipocytes

wandering cells: plasm cell, free macrophages, mesenchymal cells, neutrophils, eosinophils, lymphocytes

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9
Q

What is adipose tissue?

A

Loose connective tissue that contains adipocytes

function: provides padding and cushions shock; insulates (reduces heat loss); stores energy

location: deep to the skin, especially at sides, buttocks, breasts, padding around eyes and kidneys

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10
Q

What is reticular tissue?

A

Loose connective tissue that contains reticular fibres (appears webby)

function: provides supporting framework

location: liver, kidney, spleen, lymph nodes, and bone marrow

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11
Q

What is dense regular connective tissue?

A

Contains fibroblasts and collagen fibres, one directional.

Forms tendons (muscle to bone connections) and ligaments (bone to bone connections) which are poorly vascularized, and deep fasciae around muscles which are highly vascularized

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12
Q

What is dense irregular connective tissue?

A

Contains collagen fibre bundles, fibroblasts (not usually visible)W. Located in dermis, visceral organ capsules, perichondrium, periosteum

multidirectional, looks like burger meat lol

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13
Q

What is elastic connective tissue?

A

Contains elastic fibres and fibroblasts

founds in elastic ligaments between vertebrae, walls of blood vessels

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14
Q

What is blood and lymph?

A

Fluid connective tissue; the continuous circulation of extracellular fluid, including the fluid connective tissue lymph

blood process: (idk if necessary)

1) arteries carry blood away from heart into tissues
2) capillaries exchange blood and interstitial fluid
3) at capillary networks blood pressure forces water and small solutes out of the bloodstream into surrounding interstitial fluid (filtration)
4) lymph forms as interstitial fluid enters lymphatic systems
5. lymphatic vessels form a network that returns lymph to larger veins near the heart
6) veins carry blood from capillary beds back to heart

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15
Q

What are blood cells?

A

Red blood cells - erythrocytes
White blood cells (monocytes, lymphocytes, eosinophil, neutrophil, basophil) - leukocytes
Platelets - thrombocytes

16
Q

What is cartilage?

A

Cells (chondrocytes) are in cavities called lacunae and produce collagen in a gel-like matrix

cushions the end of long bones, supports the airway, form epiphyseal (growth) plates, and intervertebral discs

avascular

17
Q

What is bone?

A

Contains a very hard matrix of calcium salts and a large number of collagen fibres

bone cells called osteoblasts and osteoclasts reside in lacunae (cavities)

bone is quite vascularized

major site of hematopoiesis

only a small volume of bone is ground substance, 2/3 of the matrix is calcium salts (CaPO4) and the remaining is collagen fibres and 2% cells

18
Q

What is hyaline cartilage?

A

Contains chondrocytes in lacunae in matrix, kinda looks like larva in water lol

function: provides stiff but somewhat flexible support; reduces friction between bony surfaces

locations: between tips of ribs and bones of sternum; covering bone surfaces at synovial joints; supporting larynx; trachea, and bronchi; forming part of nasal septum

19
Q

What is elastic cartilage?

A

Contains chondrocytes in lacunae as well as elastic fibres in matrix

function: provides support but tolerates distortion without damage and returns to original shape

location: auricle of external ear; epiglottis; auditory tube; cuneiform cartilages of larynx

20
Q

What is fibrous cartilage?

A

Wavy collagen fibres and scattered lacune containing chondrocytes

function: resists compression; prevents bone to bone contact; limits relative movement

location: pads within knee joint; between pubic bones of pelvis; intervertebral discs

21
Q

What is perichondrium?

A

Found around the perimeter of all 3 types of cartilage and has

1) outer, fibrous layer of dense irregular connective tissue
2) inner, cellular layer (fibroblasts and chondrogenic cells)

bone also has this

22
Q

Appositional (width) vs Interstitial (height) growth of cartilage

A
23
Q

What are the 4 types of membranes?

A

1) Mucous

-simple columnar epithelium
-lamina propria (areolar tissue)
-cilia (i think)

2) Serous

-transudate (serous fluid)
-mesothelium
-areolar tissue

3) Cutaneous

-stratified squamous epithelium
-areolar tissue
-dense irregular tissue

4) Synovial

-hyaline tissue
-synovial fluid
-capsule
-capillary
-adipocytes
-areolar tissue
-epithelium
-bone

24
Q

What is fasciae?

A

Connective tissue layers and wrappings that support and surround organs, consisting of 3 layers/types

1) superficial fascia: provides insulation and padding

-between skin and underlying organs
-areolar and adipose loose connective tissue
-known as the subcutaneous/hypodermis

2) deep fascia: layers like plywood providing resistance

-forms a strong, fibrous internal framework
-dense connective tissues
-bound to capsules, tendons, and ligaments

3) subserous fascia: provides padding

-areolar loose connective tissue
-between serous membranes and deep fascia

25
Q

What is the relative composition of muscle and neural tissue to the weight of the body?

A

50% Muscle tissue
45% Connective tissue
3% Epithelial tissue
2% Neural tissue