CONNECTIVE TISSUES Flashcards
herarchy of struccture from cells to systems
cells
tissues
organs
systems
it lines surfaces in the body
epithelial tissues
is made up of fibers that contract
muscle tissues
it consists of cells with projections that transmit electrical signals
nervous tissues
acts as padding under skin and elsewhere
loose connective tissue
these are connective cells in hard or stiff extracellular matrix
bone and cartilage
is a connective tissues made up of cells in a liquid matrix
blood
for protection, secretion, and absorption
Epithelial tissue
it is for support, bind, and protect organs
Connective tissue
it is for contraction
Muscle tissue:
it Develops from the mesoderm
CONNECTIVE TISSUE
it is for information to other cells
Nervous tissue:
it Connects, supports, binds, or separates different types of tissues and organs in the body
CONNECTIVE TISSUE
it is Found in b/w other tissues everywhere in the body, including nervous system
CONNECTIVE TISSUE
3 composition of connective tissues
micture of cells
fibers
ground substance
6 mixtures of cells
FIBROBLASTS
MACROPHAGES
MAST CELLS
PLASMA CELLS
LEUKOCYTES
ADIPOCYTES (FAT CELLS)
it is the Most common cells in connective tissue.
FIBROBLASTS
- Their nuclei are ovoid or spindle shaped and can be large or
small in size depending on their stage of cellular activity.
Synthesis ECM and collagen
FIBROBLASTS
are Highly phagocytic cells that are derived from blood monocytes.
MACROPHAGES
With conventional staining, ———— are very difficult to
identify unless they show visible ingested material inside their
cytoplasm.
MACROPHAGES
the Bone marrow origin and are distributed chiefly around small
blood vessels.
MAST CELLS
They are oval to round in shape, with a centrally placed nucleus.
MAST CELLS
Derived from B lymphocytes
PLASMA CELLS
They are oval shaped and have the ability to secrete antibodies
that are antigen specific.
PLASMA CELLS
White blood cells, are considered the transient cells of connective tissue.
LEUKOCYTES
They migrate from the blood vessels into connective tissue by the process of diapedesis.
LEUKOCYTES
LEUKOCYTES migrate from the blood vessels into connective tissue by the process of
diapedesis.
Arise from undifferentiated mesenchymal cells of connective tissue. They gradually accumulate
ADIPOCYTES
which results in a significant flattening of the nucleus in the
periphery of the cell.
cytoplasmic fat
is a clear, viscous substance with a high
water content, but with very little morphologic structure.
Ground substance
When stained with basic dyes, it
appears amorphous, it appears as a clear space.
Ground substance
basic dyes
(periodic acid-Schiff [PAS])
Its major component is Glycosaminoglycans (GAGs), which
are long, un-branched chains of polysaccharides with
repeating disaccharide units.
Ground substance
are long, un-branched chains of polysaccharides with
repeating disaccharide units.
Glycosaminoglycans (GAGs),
most of these are covalently bonded to a large central protein to form larger molecules called proteoglycans.
Glycosaminoglycans (GAGs),
Most GAGs are covalently bonded to a large central protein to
form larger molecules called
proteoglycans
3 fibers
collagen
elastic
reticular
are the most common and widespread
fibers in connective tissue.
COLLAGEN FIBERS
it occupies 25-35% of body
Collagen
molecule (tropo-collagen) is a product of the
fibroblast.
collagen
is 300 nm in length and consists
of three polypeptide amino acid chains.
collagen molecule
have a very resilient nature (stretch and
recoil), which is important in areas like the lungs, aorta,
and skin.
Elastic fibers
They are composed of two proteins, elastin and fibrillin,
and do not have a banding pattern.
Elastic fibers
two proteins in elastic fibers
elastin and fibrillin
these proteins do not have a banding pattern.
elastin and fibrillin
are small-diameter fibers.
RETICULAR FIBERS
are Supporting mesh in soft tissues(liver,bone marrow and
lymphatic system)
RETICULAR FIBERS
4 types of connective tissue
- Connective Tissue Proper
- Specialized Connective Tissues
- Supportive connective Tissues
- Fluid connective tissue
3 connective tissues proper
Dense irregular CT
Loose CT
Dense regular CT
refers to the high abundance of collagen
fibers (but fewer cells) compared to loose connective
tissue.
“Dense”
indicates that the orientation of the fiber
bundles is in many different directions (or randomly
oriented bundles).
“Irregular”
Contains mostly collagen fibers with a lesser
number of other fibers such as elastic fibers.
DENSE IRREGULAR CT
this connective tissue provide strength.
dense irregular ct