CONNECTIVE TISSUES Flashcards

1
Q

Connective tissue 2 divisions:

A

CT Proper and Specialized

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2
Q

Connective tissues specialized:

A

Adipose, muscle, bones

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3
Q

Types of Connective tissues:

A

Extracellular Matrix, Protein, Fibers, Collagen, Water

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4
Q

less number of cells; Facilitates nutrient and gas (02 and co2) transfer.

A

Extracellular Matrix

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5
Q

substances that help our body. Mediator of metabolism

A

protein

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6
Q

Amorphous, homogenous, transparent, and hydrated gel (h2o)

A

Ground substance

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7
Q

main constituent. Core protein glycosaminoglycans enter

A

Proteoglycans

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8
Q

they bind to proteoglycans

A

Glycosaminoglycans

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9
Q

(backbone) – proteoglycans kumakapit sa hyaluronic acid specifically sa Link Protein

A

Hyaluronic acid

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10
Q

(links proteoglycan na may kasamang proteoglycans sa hyaluronic acid. Special glycosaminoglycan

A

Link Protein

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11
Q

Types of Glycosaminoglycans

A

Hyaluronic acid, link protein, keratan, sulfate, chondroitin sulfate, dermatan sulfate, heparan sulfate

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12
Q

Multiadhesive Glycoproteins

A

Fibrillin, fibronectin, laminin, thrombospondin, etc.

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13
Q

mediates cellular migration, cell adhesion, tissue regeneration

A

Fibronectin

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14
Q

integrins type IV collagen and proteoglycans. It is a binding site for these certain substances/proteins.

A

Laminin

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15
Q

The force that keeps the water outside the blood vessels or tissues

A

Hydrostatic pressure

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15
Q

The force that keeps the water outside the blood vessels or tissues

A

Hydrostatic pressure

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16
Q

The force that keeps the water inside the blood vessels.

A

Osmotic pressure

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17
Q

build-up of interstitial fluid in connective tissues

A

Edema

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18
Q

Hereditary diseases involving specific enzymes that degrades GAGs.

They lack enzymes. No. of GAGs will be increased resulting to magiiba yung appearance ng patients kasi yung tissues ay abnormal if sosobra yung GAGs

A

Hunter, Hurler, Sanfilippo

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19
Q

Consists mainly of fibroblasts.
These fibroblasts produces different substances such as proteoglycans.
* Spindle-like in shape

A

Embryonic mesenchyme

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20
Q

produce and maintain most of the tissue’s extracellular components

A

Fibroblasts

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21
Q

mainly for defense

A

Leukocytes

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22
Q

mediates some inflammatory responses. Works together with basophils.

A

Mast Cells

22
Q

mediates some inflammatory responses. Works together with basophils.

A

Mast Cells

23
Q

Mainly fats, for cushioning and structural component of adipose tissues

A

Adipocytes

24
Q

mature quiescent (inactive/sleeping) fibroblasts

A

Fibrocyte

25
Q
  • Main phagocytic.
  • For bacterial infection
  • Predominant sa circulation
A

Neutrophil

26
Q
  • Its nucleus is typically closer to the size of the RBCs.
  • One big oval shape.
  • Its main function is for cellular defense and production of antibodies.
  • Walang granules
  • Almost the same to macrophages
  • Increased lymphocyte:
    o intracellular infections/viral infections
A

Lymphocyte

26
Q
  • Its nucleus is typically closer to the size of the RBCs.
  • One big oval shape.
  • Its main function is for cellular defense and production of antibodies.
  • Walang granules
  • Almost the same to macrophages
  • Increased lymphocyte:
    o intracellular infections/viral infections
A

Lymphocyte

27
Q

orchestrator or mastermind of immune responses. They will produce different substances.

A

T helper:

28
Q

produces toxic substances to kill intracellular pathogens. Bind to the cell to kill it. Mainly this is defense for intracellular pathogens.

A

T cytotoxic

29
Q

It can mature into plasma cells
Plasma cells will produce different antibodies to the surface.
Then these antibodies will detach and will try to find yung nagca-cause ng disease.

A

B cells

30
Q
  • Kidney bean-shaped, irregular cytoplasm
  • Clean up crew.
  • Macrophage cleans bacteria, debris, and affected cells. → for elimination
    o Sa circulation, onti lang _____ then sa tissues ay macrophages.
A

Monocyte

31
Q

Bi-lobe nucleus.
* Increased during parasitic infection

A

Eosinophil

32
Q
  • Typically 0-1 lang sa differential cell count.
  • Pag tumaas, may sakit na.
  • Release heparin and histamine.
  • The rarest.
A

Basophil

33
Q

natural anti-coagulant of the body

A

Heparin

34
Q

Liquid form sa body

A

Anti-coagulant

35
Q

mediation of immune response

A

Histamine

36
Q

Types of Fibers

A
  • Collagen
  • Reticular
  • Elastic
37
Q

Collagen fibers made up of type I collagen

A

Fibrillar collagen

38
Q

o Laminae
o The one connecting basal lamina and epithelium

A

Network or sheet-forming collagens

39
Q

Anchors tissues to basement membrane

A

Linking/anchoring collagens

40
Q

pre-cursor of collagen

A

Procollagen alpha chains

41
Q

o Local swelling caused by abnormally large amounts of collagen that form in scars of the skin
o Due to certain hereditary defect, sumosobra yung collagen during tissue repair.
o Mostly black people/African people yung nagkakaroon ng keloids

A

Keloids

42
Q

Found in delicate connective tissue of many organs
* Argyrophillic – needs silver stain (to be able to see)
* PAS-positive (Periodic Acid Schiff)
* Delicate reticular networks serve as the supportive stroma for the parenchymal secretory cells and rich microvasculature
o Example: liver and endocrine glands
* Mainly made up of type lll collagen (found in delicate connective tissues)

A

Reticular fibers

43
Q

Structure or supportive part of the matrix. They hold the structure or the tissue together

A

Stroma

44
Q

Constituents of the matrix

A

Stroma,Parenchyma

45
Q

The functional part. Usually consists of different cells with certain functions (laman)

A

Parenchyma

46
Q
  • Have rubberlike properties that allow tissue containing these fibers to be stretched or distended and return to their original shape
  • Not strongly acidophilic
  • Can be seen in the lungs, capsules, pericardium, urothelium (composed of transitional epithelial tissues)
A

Elastic fibers

47
Q

a disease characterized by a lack of resistance in tissues rich in elastic fibers

A

Marfan Syndrome

48
Q

Types of connective tissues

A

Loose connective,Dense regular,Dense irregular,Reticular,Mucoid

49
Q

Forms a layer beneath the epithelial lining of many organs and filling the spaces between fibers of muscle and nerve
* Typically contains cells, fibers, and ground substance in roughly equal parts
* Flexible and not very resistant to stress

Additional:
* Mas maluwag, mas stretchy as compared to dense connective tissue
* Decreased collagen, increased yung fibrolasts kasi siya yung mas malapit sa balat.
* Fibrolasts produces substances for tissue repair.

A

Loose connective tissue

50
Q
  • Similar components as loose connective tissue but with fewer cells
  • Type I collagen predominant
  • Dense irregular – randomly interwoven collagen granules w/ no definite orientation
  • Skin
  • Dense regular – aligned in parallel for great resistance to prolonged or repeated stresses from the same direction
  • Tendons and ligaments
    Additional:
  • Fewer cells, increased collagen
  • Mas strong structurally as compared to loose.
A

Dense Connective tissues

51
Q
  • Abundance of type III collagen fibers
  • Delicate network that supports various types of cells
  • Provides a framework with specialized microenvironments for cells in hemopoietic tissue and some lymphoid organs
  • Lymphoid organs example: bones/bone marrow
A

Reticular tissue

52
Q

– modified fibroblasts na makikita sa reticular tissue

A

Reticular cells

53
Q
  • Principal component of the fetal umbilical cord
  • With abundant ground substance composed chiefly of hyaluronan
  • Sparse collagen fibers and scattered fibroblasts
    Additional:
  • Fetal umbilical cord (whartons jelly)
  • Hyaluronan: protein
  • Developing pa kasi connected sa fetus
  • Maraming fibroblasts
A

Mucoid connective tissue