CONNECTIVE TISSUES Flashcards
Connective tissue 2 divisions:
CT Proper and Specialized
Connective tissues specialized:
Adipose, muscle, bones
Types of Connective tissues:
Extracellular Matrix, Protein, Fibers, Collagen, Water
less number of cells; Facilitates nutrient and gas (02 and co2) transfer.
Extracellular Matrix
substances that help our body. Mediator of metabolism
protein
Amorphous, homogenous, transparent, and hydrated gel (h2o)
Ground substance
main constituent. Core protein glycosaminoglycans enter
Proteoglycans
they bind to proteoglycans
Glycosaminoglycans
(backbone) – proteoglycans kumakapit sa hyaluronic acid specifically sa Link Protein
Hyaluronic acid
(links proteoglycan na may kasamang proteoglycans sa hyaluronic acid. Special glycosaminoglycan
Link Protein
Types of Glycosaminoglycans
Hyaluronic acid, link protein, keratan, sulfate, chondroitin sulfate, dermatan sulfate, heparan sulfate
Multiadhesive Glycoproteins
Fibrillin, fibronectin, laminin, thrombospondin, etc.
mediates cellular migration, cell adhesion, tissue regeneration
Fibronectin
integrins type IV collagen and proteoglycans. It is a binding site for these certain substances/proteins.
Laminin
The force that keeps the water outside the blood vessels or tissues
Hydrostatic pressure
The force that keeps the water outside the blood vessels or tissues
Hydrostatic pressure
The force that keeps the water inside the blood vessels.
Osmotic pressure
build-up of interstitial fluid in connective tissues
Edema
Hereditary diseases involving specific enzymes that degrades GAGs.
They lack enzymes. No. of GAGs will be increased resulting to magiiba yung appearance ng patients kasi yung tissues ay abnormal if sosobra yung GAGs
Hunter, Hurler, Sanfilippo
Consists mainly of fibroblasts.
These fibroblasts produces different substances such as proteoglycans.
* Spindle-like in shape
Embryonic mesenchyme
produce and maintain most of the tissue’s extracellular components
Fibroblasts
mainly for defense
Leukocytes