Connective Tissue Block 1 Flashcards
There is a wide variety it what in the body?
Connective tissue
What are the seven fictions if connective tissue
- structural support - protection - strength - cushions - elasticity - fat storage - tissue repair
Generally connective tissue has what
Large amounts of interstitial space
Most connective tissue is what
Vascular and innervated
What helps support endothelium tissue
Connective tissue
What are the two cell types in connective tissue
Permanent and migratory cells
What are the 3 permanent cells in connective tissue
- fibroblasts - adipose cells - chondrocytes and osteocytes
What are the four types if migratory cells
Leukocytes Macrophages Mast cells Plasma cell
What contains histamine and heparin
Last cell granules
What is important to the immune systems
Mitochondria
What does the matrix of the ct contain
Ground substance Protein fibers and glycoproteins
Where are the glycoproteins in the ground substance
They are embedded in it
What is ground substance
The semi fluid gel that is colorless and transparent and amorphous ( without definite shape)
Ground substance contains what
GAG’s aka mucoploysacchsrides Protein fibers and structural protein
There are 7 different GAG’s what are they
- hyaluronic acid - chondrotin-4-sulfate - chondrotin-6- sulfate - dermatan sulfate -heparan sulfate - heparin sulfate - keratan sulfate
Which GAG IS NOT sulfated
acid
The sic GAG that bind to the core linear protein are called what
Proteoglycans
Proteoglycans have what charge
They are negative and they are hydrophilic
What are the two main types of ct protein fibers
-collagen and elastin
What is a polymer of troop collagen and has 28 types identified by Roman numerals?
Collagen
What has branches and is good for stretch and recall and is also a polymers of tropeoeladtin
Elastin
What is the most abundant protein in the body makes up 25%
Collagen
What is type 1 collagen
The most common one and is found in the dermis - tendons - ligaments - bone - capsules And most fibrous supporting tissues
Type 11 collagen is found where
Hyaline cartilage
What allows for the framework of the liver, bone marrow and lymphoid tissue (reticulin)
Type 3 collagen
Which collagen is found in the basil lamina of epithelial cells
Type 4
What are some examples of some types of different structures glycoproteins
Fibrilin Fibronectin Laminin Entactin Tenascin
What has an unclear function but is thought to provide structural support
Glycoproteins
What kind of fibers are in lymph nodes
Reticular fibers (reticulin)
What are the five types of connective tissue proper
Loose Dense Elastic Reticular Adipose
What are the three specialized types of ct
Blood Bone Cartilage
What is loose connective tissue
Very flexible and has many fibroblasts and some macrophages. All cells and fibers may be present
What does loose (areolar ) tissue do
Supports structures that are under pressure Usually below basil lamina of epithelial tissue Surrounds lymphatic blood vessels Surrounds bundles of muscle cells Is part of the skin
Which kind if tissue is dense, strong and resist stress It is also thigh and mainly densely packed
Dense ct
What has fewer cells and ground substance because it snore dense
Dense ct
Describe dense irregular ct
It has collagen bundles that are not parallel It covers the dermis and organ capsules
Describe regular ct
Collagen bundles that are parallel Good for stretching and recoil Covers tendons and ligaments
Dense regular ct had a lining on it that you can see in a slide what is it
Synovium lining
What is the main fiber component in elastic fiber
Elastin
Where is elastic tissue found
In areas that stretch and recoil
Elastic tissue is found where
Dermis Lungs Large blood vessels
What is the main fiber found in reticular tissue
Reticulin
Reticular tissue is what type of collagen
Type 3
What does reticular fiber do
It provides a supportive network of branches fibers
Where is reticular fiber located
In the stroke of the endocrine glands and the lymphatic organs
What are the two toes of adipose tissue
White and brown
Which adipose tissue is highly bascularized stores energy and insulates This also stores energy and secretes leptin
White adipose tissue
What is leptin
An anti obesity hormone secreated by white adipose tissue
Where is white adipose tissue usually found
The hypodermis and next to the heart and kidney
What tissues are extremely vascularized and contain more mitochondria then a normal cell Also insulates and produces hear in newborns and hibernating animals
Brown adipose tissue
Which tissue atrophied with age and there is little found in the adult
Brown adipose tissue
Which tissue is composed of adipose cells surrounded by reticular fibers?
Brown adipose tissue